MHC class I antigen (HLA-A) is a 317-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: Q8WLS4.
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The mean pLDDT of this model is 89.5 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 84% |
| 70 to 90 | Confident: backbone generally right | 3% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 12% |
What pLDDT means and how to read it
Cell membrane, Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9J4U | X-ray | 2.17 Å | A=25-299 |
| 9PIX | X-ray | 2.35 Å | A=25-300 |
| 9PKC | X-ray | 2.5 Å | A=25-300 |
| 9PKF | X-ray | 2.6 Å | A=25-300 |
| 9PKV | EM | 2.72 Å | A=25-300 |
| 3HG1 | X-ray | 3.0 Å | A=25-300 |
| 9C96 | EM | 3.0 Å | A=25-300 |
| 9K2I | X-ray | 3.05 Å | A/F/K/P=25-299 |
| 9FE1 | EM | 3.1 Å | A=25-300 |
| 9HKQ | EM | 3.3 Å | B=25-298 |
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