Q8WW35: Dynein light chain Tctex-type protein 2B (DYNLT2B)

Dynein light chain Tctex-type protein 2B (DYNLT2B) is a 142-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q8WW35.

Gene
DYNLT2B
Organism
Homo sapiens
Length
142 residues
Mean pLDDT
85.8
Model
AF-Q8WW35-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 85.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate70%
70 to 90Confident: backbone generally right13%
50 to 70Low: treat with caution4%
Below 50Very low: often disordered regions13%

What pLDDT means and how to read it

Function

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. Required for proper retrograde ciliary transport

Subunit structure

Light chain of the cytoplasmic dynein complex 2, a multisubunit complex composed at least of eleven different proteins (PubMed:25205765, PubMed:26044572). The cytoplasmic dynein 2 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs). Among them, a heavy chain…

Subcellular location

Dynein axonemal particle

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8RGIX-ray2.02 ÅB=2-142
8J07EM4.1 Ål7/n7/p7/r7=1-142

More AlphaFold highlights

About this viewer

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