Q96DF8: Splicing factor ESS-2 homolog (ESS2)

Splicing factor ESS-2 homolog (ESS2) is a 476-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q96DF8.

Gene
ESS2
Organism
Homo sapiens
Length
476 residues
Mean pLDDT
67.3
Model
AF-Q96DF8-F1 v6
Model created
1 Aug 2025
PDB structures
3

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Model confidence (pLDDT)

The mean pLDDT of this model is 67.3 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate13%
70 to 90Confident: backbone generally right31%
50 to 70Low: treat with caution33%
Below 50Very low: often disordered regions23%

What pLDDT means and how to read it

Function

May be involved in pre-mRNA splicing

Subunit structure

Identified in the spliceosome C complex (PubMed:11991638). Interacts with FRA10AC1 (PubMed:34694367)

Subcellular location

Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8C6JEM2.8 Å4=1-476
9FMDEM3.3 Å3=1-476
8RO2EM3.5 Å3=1-476

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