Bcl-2-modifying factor (BMF) is a 184-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q96LC9.
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The mean pLDDT of this model is 61.4 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 14% |
| 70 to 90 | Confident: backbone generally right | 13% |
| 50 to 70 | Low: treat with caution | 41% |
| Below 50 | Very low: often disordered regions | 33% |
What pLDDT means and how to read it
May play a role in apoptosis. Isoform 1 seems to be the main initiator
Interacts with MCL1, BCL2, BCL2L1/BCL-Xl, BCL2A1 and BCL2L2/BCL-w. Interacts with the myosin V actin motor complex through its binding to DLC2 (By similarity)
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8IQM | X-ray | 1.97 Å | B=130-150 |
| 7CNU | X-ray | 2.0 Å | C=63-82 |
| 8R58 | X-ray | 2.31 Å | B=1-19 |
| 8IQK | X-ray | 2.88 Å | B/D/F/H=127-151 |
| 8IQL | X-ray | 2.96 Å | B/D=127-151 |
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