Apoptosis-inducing factor 3 (AIFM3) is a 605-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q96NN9.
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The mean pLDDT of this model is 88.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 81% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 11% |
What pLDDT means and how to read it
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential
Mitochondrion
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6SK8 | X-ray | 1.87 Å | C/D=2-9 |
| 6SK2 | X-ray | 1.9 Å | D/F=5-8 |
| 6SJZ | X-ray | 2.0 Å | E/F=2-9 |
| 5O9V | X-ray | 2.2 Å | C/D=2-9 |
| 6QRM | X-ray | 2.3 Å | C/D=2-11 |
| 6SK3 | X-ray | 2.7 Å | C/D=2-9 |
| 6SKJ | X-ray | 2.8 Å | C/D=2-9 |
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