Q96PX8: SLIT and NTRK-like protein 1 (SLITRK1)

SLIT and NTRK-like protein 1 (SLITRK1) is a 696-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q96PX8.

Gene
SLITRK1
Organism
Homo sapiens
Length
696 residues
Mean pLDDT
76.5
Model
AF-Q96PX8-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 76.5 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate52%
70 to 90Confident: backbone generally right21%
50 to 70Low: treat with caution4%
Below 50Very low: often disordered regions23%

What pLDDT means and how to read it

Function

It is involved in synaptogenesis and promotes excitatory synapse differentiation (PubMed:27273464, PubMed:27812321). Enhances neuronal dendrite outgrowth (PubMed:16224024, PubMed:19640509)

Subunit structure

Can form homodimers; homodimerization requires repeat LRR 2 (PubMed:27273464). Interacts with YWHAB, YWHAE, YWHAG, YWHAH, SFN, YWHAQ and YWHAZ (PubMed:19640509)

Subcellular location

Membrane, Secreted, Synapse

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
4RCAX-ray2.99 ÅB=20-264
4RCWX-ray3.19 ÅA/B=341-580

More AlphaFold highlights

About this viewer

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