Q99LE1: RILP-like protein 2 (Rilpl2)

RILP-like protein 2 (Rilpl2) is a 197-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q99LE1.

Gene
Rilpl2
Organism
Mus musculus
Length
197 residues
Mean pLDDT
77.8
Model
AF-Q99LE1-F1 v6
Model created
1 Aug 2025
PDB structures
1

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Model confidence (pLDDT)

The mean pLDDT of this model is 77.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate50%
70 to 90Confident: backbone generally right19%
50 to 70Low: treat with caution11%
Below 50Very low: often disordered regions20%

What pLDDT means and how to read it

Function

Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines (By similarity). Plays a role in cellular protein transport, including protein transport away from primary cilia (PubMed:23264467). May function via activation of RAC1 and PAK1 (By similarity)

Subunit structure

Homodimer (PubMed:23798443). Interacts with RAC1 (By similarity). Interacts (via N-terminus) with MYO5A, the interaction is required for its role in dendrite formation (PubMed:23798443). Interacts with RAB8A; interaction is dependent on the phosphorylation of RAB8A on 'Thr-72' (PubMed:29125462). Interacts with RAB10 and RAB12; interaction is dependent on the phosphorylation of 'Thr-73' on RAB10…

Subcellular location

Cytoplasm, cytosol, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cell projection, cilium

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
4KP3X-ray2.4 ÅC/D=1-97

More AlphaFold highlights

About this viewer

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