Small membrane A-kinase anchor protein (C2orf88) is a 95-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9BSF0.
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The mean pLDDT of this model is 71.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 28% |
| 70 to 90 | Confident: backbone generally right | 24% |
| 50 to 70 | Low: treat with caution | 26% |
| Below 50 | Very low: often disordered regions | 21% |
What pLDDT means and how to read it
Binds to type I regulatory subunits of protein kinase A (PKA-RI) and anchors/targets them to the plasma membrane
Interacts with PKA type I regulatory subunits PRKAR1A and PRKAR1B; this interaction targets PRKAR1A and PRKAR1B to the plasma membrane (PubMed:23115245, PubMed:27028580). Also binds to type II regulatory subunits, but at a tenfold lower affinity (PubMed:23115245)
Cell membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5HVZ | X-ray | 2.0 Å | C=56-79 |
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