Transcription factor HFR1 (HFR1) is a 292-residue protein from Arabidopsis thaliana. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9FE22.
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The mean pLDDT of this model is 57.9 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 9% |
| 70 to 90 | Confident: backbone generally right | 9% |
| 50 to 70 | Low: treat with caution | 44% |
| Below 50 | Very low: often disordered regions | 38% |
What pLDDT means and how to read it
Atypical bHLH transcription factor that regulates photomorphogenesis through modulation of phytochrome (e.g. PHYA) and cryptochrome signalings (PubMed:10995393, PubMed:11090209, PubMed:19482971, Ref.4). Suppresses the transcriptional regulation activity of PIF4 by forming non-DNA-binding heterodimer
Binds to FHY1 and FHL. Forms PHYA/FHY1/HFR1 complex (PubMed:19482971). Homodimer and heterodimer with PIF3. Do not interact alone with either phytochrome A (phyA) or B (phyB), but REP1/PIF3 complex binds to phyA and phyB, preferentially to the Pfr forms. Forms non-functional heterodimer with PRE6, causing liberation of PIF4 from the transcriptionally inactive complex HFR1-PIF4. Repressed when…
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6QTV | X-ray | 1.31 Å | B=57-66 |
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