PDZ domain-containing protein 7 (PDZD7) is a 1033-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9H5P4.
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The mean pLDDT of this model is 56.7 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 14% |
| 70 to 90 | Confident: backbone generally right | 23% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 56% |
What pLDDT means and how to read it
In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links. Blocks inhibition of adenylate cyclase activity mediated by ADGRV1
Homodimerizes (via PDZ2 domain). Component of USH2 complex, composed of ADGRV1, PDZD7, USH2A and WHRN. Interacts (via PDZ domains) with WHRN; the interaction is direct (By similarity). Interacts with USH1G (PubMed:19028668). Interacts with ADGRV1 (via the cytoplasmic region) (PubMed:20440071). Interacts with USH2A (via the cytoplasmic region) (PubMed:20440071). Interacts with MYO7A (via…
Cell projection, cilium, Nucleus, Cell projection, stereocilium
Compare the prediction with experimentally determined structures of the same protein:
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