PRKR-interacting protein 1 (PRKRIP1) is a 184-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9H875.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 80.5 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 57% |
| 70 to 90 | Confident: backbone generally right | 14% |
| 50 to 70 | Low: treat with caution | 15% |
| Below 50 | Very low: often disordered regions | 14% |
What pLDDT means and how to read it
Required for pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:30705154). Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity)
Component of the pre-catalytic and post-catalytic spliceosome complexes (PubMed:28502770, PubMed:30705154). Interacts with EIF2AK2 (By similarity)
Nucleus, Nucleus, nucleolus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8C6J | EM | 2.8 Å | D=1-184 |
| 6ICZ | EM | 3.0 Å | X=1-184 |
| 6QDV | EM | 3.3 Å | D=20-142 |
| 9FMD | EM | 3.3 Å | 1=1-184 |
| 5XJC | EM | 3.6 Å | X=1-184 |
| 7W5A | EM | 3.6 Å | 2=1-184 |
| 7W5B | EM | 4.3 Å | 2=1-184 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.