Beta-parvin (PARVB) is a 364-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9HBI1.
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The mean pLDDT of this model is 81.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 54% |
| 70 to 90 | Confident: backbone generally right | 24% |
| 50 to 70 | Low: treat with caution | 9% |
| Below 50 | Very low: often disordered regions | 14% |
What pLDDT means and how to read it
Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration
Interacts with DYSF. Interacts with ILK, ARHGEF6, PXN (via LD motifs), ACTN2 and actin
Cell junction, focal adhesion, Cell membrane, Cytoplasm, cytoskeleton, Cell projection, lamellipodium, Cytoplasm, myofibril, sarcomere, Cytoplasm, myofibril, sarcomere, Z line
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4EDM | X-ray | 2.0 Å | A/B=235-364 |
| 4EDL | X-ray | 2.1 Å | A/B/C/D/E/F=235-364 |
| 4EDN | X-ray | 2.9 Å | A/B/C/D/E/F/G/H/I/J=235-364 |
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