Glycoprotein G (G) is a 602-residue protein from Nipah virus. This is its AlphaFold structure prediction, created 1 Jan 2024. UniProt accession: Q9IH62.
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The mean pLDDT of this model is 81.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 62% |
| 70 to 90 | Confident: backbone generally right | 13% |
| 50 to 70 | Low: treat with caution | 13% |
| Below 50 | Very low: often disordered regions | 12% |
What pLDDT means and how to read it
Interacts with host ephrinB2/EFNB2 or ephrin B3/EFNB3 to provide virion attachment to target cell. This attachment induces virion internalization predominantly through clathrin-mediated endocytosis
Homotetramer; disulfide-linked (PubMed:35239409, PubMed:38582870, PubMed:38773072, PubMed:39134522). Interacts with host EFNB2; this interaction allows the virus entry into the host cell (PubMed:16007075, PubMed:18488039, PubMed:18815311). Interacts with host EFNB3; this interaction allows the virus entry into the host cell (PubMed:16477309, PubMed:18632560). Interacts with the fusion…
Virion membrane, Host cell membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2VSM | X-ray | 1.8 Å | A=188-602 |
| 2VWD | X-ray | 2.25 Å | A/B=183-602 |
| 3D11 | X-ray | 2.31 Å | A=176-602 |
| 8JA5 | X-ray | 2.79 Å | A/D=186-602 |
| 8K3C | EM | 2.88 Å | A/B=131-601 |
| 8K0D | EM | 2.94 Å | A/B=200-601 |
| 3D12 | X-ray | 3.0 Å | A/D=176-602 |
| 9LU3 | X-ray | 3.0 Å | A/B=176-602 |
| 9LUE | EM | 3.03 Å | G=177-602 |
| 8K0C | EM | 3.18 Å | A/B=97-601, C/D=96-153 |
| 7TXZ | EM | 3.2 Å | A/B/C/D=70-601 |
| 6VY5 | X-ray | 3.4 Å | A=183-602 |
| 7TY0 | EM | 3.5 Å | A/B/C/D=70-601 |
| 8XPY | EM | 3.63 Å | A=1-602 |
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