Rho guanine nucleotide exchange factor 9 (Arhgef9) is a 493-residue protein from Rattus norvegicus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9QX73.
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The mean pLDDT of this model is 83.5 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 59% |
| 70 to 90 | Confident: backbone generally right | 24% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 14% |
What pLDDT means and how to read it
Acts as a guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters
Interacts with GPHN
Cytoplasm, Postsynaptic density
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2DFK | X-ray | 2.15 Å | A/C=71-463 |
| 4MT7 | X-ray | 3.5 Å | A=10-493 |
| 4MT6 | X-ray | 5.5 Å | A=1-456 |
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