Sal-like protein 4 (SALL4) is a 1053-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9UJQ4.
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The mean pLDDT of this model is 51.1 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 3% |
| 70 to 90 | Confident: backbone generally right | 21% |
| 50 to 70 | Low: treat with caution | 10% |
| Below 50 | Very low: often disordered regions | 67% |
What pLDDT means and how to read it
Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells
Interacts with POU5F1/OCT4 (PubMed:23012367). Interacts with NANOG (By similarity). Interacts with BEND3 (PubMed:21914818). Interacts with NSD2 (via PHD-type zinc fingers 1, 2 and 3) (By similarity). Interacts with NRBP1 (PubMed:22510880)
Cytoplasm, Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7BQV | X-ray | 1.8 Å | B=410-432 |
| 7BQU | X-ray | 1.9 Å | B=410-432 |
| 8CUC | X-ray | 2.09 Å | E/F/G/H=864-929 |
| 7Y3I | X-ray | 2.45 Å | A/B/C/D=855-930 |
| 7Y3K | X-ray | 2.5 Å | A/B=855-930 |
| 5XWR | X-ray | 2.69 Å | C/D=1-12 |
| 9NWS | EM | 2.7 Å | C=392-449 |
| 9NWT | EM | 2.7 Å | C=392-449 |
| 7Y3M | X-ray | 2.72 Å | A/B/C/F/I/J=378-453 |
| 8U16 | X-ray | 2.9 Å | C/F=379-432 |
| 8U15 | X-ray | 2.95 Å | C/F=379-432 |
| 8U17 | X-ray | 3.1 Å | C/F=370-454 |
| 6UML | X-ray | 3.58 Å | E=405-432 |
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