Q9UJW0: Dynactin subunit 4 (DCTN4)

Dynactin subunit 4 (DCTN4) is a 460-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9UJW0.

Gene
DCTN4
Organism
Homo sapiens
Length
460 residues
Mean pLDDT
84.3
Model
AF-Q9UJW0-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 84.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate64%
70 to 90Confident: backbone generally right19%
50 to 70Low: treat with caution7%
Below 50Very low: often disordered regions9%

What pLDDT means and how to read it

Function

Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules

Subunit structure

Subunit of dynactin, a multiprotein complex part of a tripartite complex with dynein and a adapter, such as BICDL1, BICD2 or HOOK3. The dynactin complex is built around ACTR1A/ACTB filament and consists of an actin-related filament composed of a shoulder domain, a pointed end and a barbed end. Its length is defined by its flexible shoulder domain. The soulder is composed of 2 DCTN1 subunits, 4…

Subcellular location

Cytoplasm, cytoskeleton, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, stress fiber, Cytoplasm, cell cortex, Cytoplasm, myofibril, sarcomere

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9B85EM3.47 ÅK=1-460
9B7JEM3.49 ÅK=1-460

More AlphaFold highlights

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