Vacuolar protein sorting-associated protein 28 homolog (VPS28) is a 221-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9UK41.
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The mean pLDDT of this model is 91.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 81% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Component of the ESCRT-I complex, a regulator of vesicular trafficking process
Component of the ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, a VPS37 protein (VPS37A to -D) and MVB12A or MVB12B in a 1:1:1:1 stoichiometry (PubMed:14505570, PubMed:18005716). Interacts with TSG101, VPS37B, VPS37C, MVB12A and MVB12B (PubMed:14505570, PubMed:15218037, PubMed:18005716). Component of an ESCRT-I complex (endosomal sorting…
Cell membrane, Late endosome membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6VME | X-ray | 2.19 Å | E/U/V/W/X/Y=1-122 |
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