Q9UUJ1: Actin-related protein 2 (arp2)

Actin-related protein 2 (arp2) is a 390-residue protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9UUJ1.

Gene
arp2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
390 residues
Mean pLDDT
93.4
Model
AF-Q9UUJ1-F1 v6
Model created
1 Aug 2025
PDB structures
5

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Model confidence (pLDDT)

The mean pLDDT of this model is 93.4 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate86%
70 to 90Confident: backbone generally right11%
50 to 70Low: treat with caution2%
Below 50Very low: often disordered regions1%

What pLDDT means and how to read it

Function

Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). During cytokinesis it colocalizes to the cortical actin patches until spetation is complete. Has a role in the mobility of these patches. Essential for viability

Subunit structure

Component of the Arp2/3 complex composed of arp2, act2, arc1/p41-ARC, arc2/p34-ARC, arc3/p21-ARC, arc4/p20-ARC and arc5/p16-ARC

Subcellular location

Cytoplasm, cytoskeleton, actin patch

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8UXWEM2.7 ÅB=1-390
8UXXEM3.2 ÅB=1-390
8E9BEM3.5 ÅB=1-390
6W17EM3.9 ÅB=1-390
6W18EM4.2 ÅB=1-390

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