IgG H chain is a 300-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: S6B2A6.
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The mean pLDDT of this model is 83.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 52% |
| 70 to 90 | Confident: backbone generally right | 28% |
| 50 to 70 | Low: treat with caution | 13% |
| Below 50 | Very low: often disordered regions | 8% |
What pLDDT means and how to read it
Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked
Cell membrane, Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5W0D | X-ray | 1.9 Å | B=20-249 |
| 6BKD | X-ray | 3.25 Å | H=23-247 |
| 6NQD | EM | 3.9 Å | C/G/K=20-121, C/G/K=125-251 |
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