1GSG: E.coli glutaminyl-tRNA synthetase

Structure of E.coli glutaminyl-tRNA synthetase complexed with trnagln and ATP at 2.8 Angstroms resolution. Determined by X-ray diffraction at 2.8 Å resolution. Released 24 Feb 1992.

Method

X-ray diffraction

Resolution

2.8 Å

Organism

Escherichia coli

Chains

2

Atoms

601

Mol. weight

87.57 kDa

Released

24 Feb 1992

Explore 1GSG in 3D Show helices and sheets RCSB PDB PDBe

Molecules and chains

>1GSG_1 TRNAGLN (chains T)
UGGGGUAUCGCCAAGCGGUAAGGCACCGGAUUCUGAUUCCGGCAUUCCGAGGUUCGAAUC
CUCGUACCCCAGCCA

>1GSG_2 GLUTAMINYL-TRNA SYNTHETASE (chains P)
SEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQ
CNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAY
VDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMAS
PFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLY
DWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRG
YTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEG
EMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAE
RVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPN
PGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNR
TVGLRDTWAKVGE

Primary citation

Structure of E. coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP at 2.8 A resolution. Rould, M.A., Perona, J.J., Soll, D. et al. Science (1989) 246:1135-1142. PubMed

Related structures

Other PDB entries of the same protein (UniProt P00962 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 1QTQ 2.25 Å, Glutaminyl-tRNA synthetase complexed with tRNA and an amino acid analog
• 4JXX 2.3 Å, Crystal structure of E coli E. coli glutaminyl-tRNA synthetase bound to tRNA(Gln)(CUG)…
• 4JXZ 2.4 Å, Structure of E. coli glutaminyl-tRNA synthetase bound to ATP and a tRNA(Gln) acceptor…
• 1GTR 2.5 Å, Structural basis of anticodon loop recognition by glutaminyl-tRNA synthetase
• 1ZJW 2.5 Å, Glutaminyl-tRNA synthetase complexed to glutamine and 2'deoxy A76 glutamine tRNA
• 4JYZ 2.5 Å, Crystal structure of E. coli glutaminyl-tRNA synthetase bound to ATP and native…
• 1EUY 2.6 Å, Glutaminyl-tRNA synthetase complexed with a tRNA mutant and an active site inhibitor
• 1NYL 2.6 Å, Unliganded glutaminyl-tRNA synthetase
• 1QRS 2.6 Å, Glutaminyl-tRNA synthetase mutant D235N complexed with glutamine transfer RNA
• 2RD2 2.6 Å, Glutaminyl-tRNA synthetase mutant C229R with bound analog…
• 2RE8 2.6 Å, Glutaminyl-tRNA synthetase mutant C229R with bound analog…
• 1EXD 2.7 Å, Crystal structure of a tight-binding glutamine tRNA bound to glutamine aminoacyl tRNA…

Browse structure collections

About this viewer

MolViewer shows 1GSG directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.