1LLA: Hemocyanin

Crystal structure of deoxygenated limulus polyphemus subunit II hemocyanin at 2.18 Å resolution: clues for a mechanism for allosteric regulation. Determined by X-ray diffraction at 2.18 Å resolution. Released 31 Jan 1994.

Method
X-ray diffraction
Resolution
2.18 Å
Organism
Limulus polyphemus
Chains
1
Atoms
5,196
Mol. weight
72.94 kDa
Ligands
CU
Released
31 Jan 1994

Explore 1LLA in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1LLA contains 44 α-helices and 23 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 44 helices, 23 β-strands

ElementResiduesLengthSheet
α-helix3-1311
α-helix16-183
α-helix33-364
α-helix411
α-helix45-473
α-helix51-6515
α-helix70-8011
α-helix86-9914
α-helix101-1033
α-helix106-1105
α-helix111-1144
α-helix116-1183
α-helix122-1309
α-helix141-1422
β-strand143-14641
α-helix156-1605
α-helix161-1644
α-helix167-17913
α-helix186-1894
α-helix196-21722
α-helix221-2255
α-helix2321
β-strand23312
α-helix234-2352
β-strand23613
β-strand241-24224
β-strand247-24824
α-helix249-2513
β-strand25213
β-strand25612
α-helix266-28217
β-strand284-28635
β-strand292-29435
α-helix300-30910
α-helix317-3204
α-helix323-33210
α-helix343-3453
α-helix347-3493
α-helix354-3563
α-helix358-37518
α-helix379-3824
α-helix383-3864
β-strand391-39996
β-strand405-416121
β-strand429-438101
β-strand442-44986
β-strand455-465111
β-strand46717
α-helix4721
β-strand47317
α-helix474-4752
α-helix476-4827
α-helix4831
β-strand484-493101
β-strand496-50386
α-helix504-5063
β-strand510-51128
α-helix517-5215
β-strand538-53928
α-helix540-5423
β-strand54811
β-strand552-562111
α-helix563-5664
α-helix580-5834
α-helix5951
α-helix609-6113
β-strand617-626101

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Hemocyanin (subunit type II)Aprotein628Limulus polyphemusP04253 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>1LLA_1 HEMOCYANIN (SUBUNIT TYPE II) (chains A)
TLHDKQIRICHLFEQLSSATVIGDGDKHKHSDRLKNVGKLQPGAIFSCFHPDHLEEARHL
YEVFWEAGDFNDFIEIAKEARTFVNEGLFAFAAEVAVLHRDDCKGLYVPPVQEIFPDKFI
PSAAINEAFKKAHVRPEFDESPILVDVQDTGNILDPEYRLAYYREDVGINAHHWHWHLVY
PSTWNPKYFGKKKDRKGELFYYMHQQMCARYDCERLSNGMHRMLPFNNFDEPLAGYAPHL
THVASGKYYSPRPDGLKLRDLGDIEISEMVRMRERILDSIHLGYVISEDGSHKTLDELHG
TDILGALVESSYESVNHEYYGNLHNWGHVTMARIHDPDGRFHEEPGVMSDTSTSLRDPIF
YNWHRFIDNIFHEYKNTLKPYDHDVLNFPDIQVQDVTLHARVDNVVHTFMREQELELKHG
INPGNARSIKARYYHLDHEPFSYAVNVQNNSASDKHATVRIFLAPKYDELGNEIKADELR
RTAIELDKFKTDLHPGKNTVVRHSLDSSVTLSHQPTFEDLLHGVGLNEHKSEYCSCGWPS
HLLVPKGNIKGMEYHLFVMLTDWDKDKVDGSESVACVDAVSYCGARDHKYPDKKPMGFPF
DRPIHTEHISDFLTNNMFIKDIKIKFHE

Ligands and cofactors

IDNameFormulaCopies
CUCopper (II) ionCu2

Water and common crystallization additives (CL, NA) are not listed.

Primary citation

Crystal structure of deoxygenated Limulus polyphemus subunit II hemocyanin at 2.18 A resolution: clues for a mechanism for allosteric regulation. Hazes, B., Magnus, K.A., Bonaventura, C. et al. Protein Sci (1993) 2:597-619. PubMed

Other PDB entries of the same protein (UniProt P04253 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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