Factor Xa - cation. Determined by X-ray diffraction at 1.64 Å resolution. Released 16 Jun 2005.
Explore 2BOK in 3D Show helices and sheets RCSB PDB PDBe
2BOK contains 10 α-helices and 25 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 17 | 1 | 1 |
| β-strand | 20-21 | 2 | 2 |
| α-helix | 22-23 | 2 | |
| β-strand | 30-34 | 5 | 3 |
| β-strand | 40-46 | 7 | 3 |
| β-strand | 51-54 | 4 | 3 |
| α-helix | 56-60 | 5 | |
| β-strand | 65-68 | 4 | 3 |
| β-strand | 82-83 | 2 | 3 |
| β-strand | 85-90 | 6 | 3 |
| β-strand | 104-108 | 5 | 3 |
| β-strand | 115 | 1 | 4 |
| β-strand | 118 | 1 | 4 |
| α-helix | 120-121 | 2 | |
| β-strand | 122 | 1 | 2 |
| α-helix | 123-124A | 3 | |
| α-helix | 125-127 | 3 | |
| α-helix | 128-131A | 5 | |
| β-strand | 135-140 | 6 | 2 |
| β-strand | 143 | 1 | 5 |
| β-strand | 151 | 1 | 5 |
| β-strand | 156-163 | 8 | 2 |
| α-helix | 165-171 | 7 | |
| β-strand | 180-183 | 4 | 2 |
| β-strand | 189 | 1 | 1 |
| β-strand | 198-203 | 6 | 2 |
| β-strand | 206-215 | 10 | 2 |
| β-strand | 226-230 | 5 | 2 |
| α-helix | 231-234 | 4 | |
| α-helix | 235-242 | 8 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 92-95 | 4 | |
| β-strand | 99-101 | 3 | 6 |
| β-strand | 108-110 | 3 | 6 |
| β-strand | 115-117 | 3 | 7 |
| β-strand | 124-126 | 3 | 7 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Coagulation factor X | A | protein | 241 | HOMO SAPIENS | P00742 (AlphaFold model) |
| Coagulation factor X | L | protein | 55 | HOMO SAPIENS | P00742 (AlphaFold model) |
>2BOK_1 COAGULATION FACTOR X (chains A) IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLM TQKTGIVSGFGRTHEKGEQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDA CQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKA K
>2BOK_2 COAGULATION FACTOR X (chains L) RKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERR
| ID | Name | Formula | Copies |
|---|---|---|---|
| 784 | [amino (4-{(3AS,4R,8AS,8BR)-1,3-dioxo-2- [3-(trimethylammonio)… | C22 H32 N5 O2 | 1 |
Water and common crystallization additives (NA) are not listed.
Quantification of Cation-Pi Interactions in Protein-Ligand Complexes: Crystal-Structure Analysis of Factor Xa Bound to a Quaternary Ammonium Ion Ligand. Scharer, K., Morgenthaler, M., Paulini, R. et al. Angew Chem Int Ed Engl (2005) 44:4400. DOI 10.1002/ANIE.200500883 · PubMed
Other PDB entries of the same protein (UniProt P00742 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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