2D7T: Human anti polyhydroxybutyrate antibody Fv

Crystal structure of human anti polyhydroxybutyrate antibody Fv. Determined by X-ray diffraction at 1.7 Å resolution. Released 12 Dec 2006.

Method
X-ray diffraction
Resolution
1.7 Å
Organism
Homo sapiens
Chains
2
Atoms
1,907
Mol. weight
28.18 kDa
Released
12 Dec 2006

Explore 2D7T in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2D7T contains 7 α-helices and 22 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain H: 4 helices, 11 β-strands

ElementResiduesLengthSheet
β-strand3-641
β-strand10-1232
β-strand18-2581
α-helix29-313
β-strand34-3962
β-strand46-5162
β-strand58-6032
α-helix62-643
β-strand68-7361
α-helix74-763
β-strand78-8361
α-helix88-903
β-strand92-9872
β-strand105-10622
β-strand110-11452
Chain L: 3 helices, 11 β-strands
ElementResiduesLengthSheet
β-strand4-743
β-strand10-1344
β-strand19-2573
β-strand33-3864
β-strand45-4954
β-strand53-5424
α-helix551
β-strand62-6763
β-strand70-7563
α-helix80-823
β-strand84-9074
α-helix961
β-strand97-9824
β-strand102-10654

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
anti polyhydroxybutyrate antibody Fv, heavy chainHprotein139Homo sapiensQ9UL95 (AlphaFold model)
anti polyhydroxybutyrate antibody Fv, light chainLprotein116Homo sapiensQ6GMX0 (AlphaFold model)
Sequence of entity 1 (H), FASTA
>2D7T_1 anti polyhydroxybutyrate antibody Fv, heavy chain (chains H)
QVQLVQSGAEVKKPGASVKVSCKASGYTFTGNYMHWVRQAPGQGLEYMGWINPKSGDTNY
AQKFQGRVTMTRDTSISTVYMEVRRLRSDDTAVYYCATGWWGMDVWGQGTLVTVSSASEQ
KLISKEDLNGSAGHHHHHH
Sequence of entity 2 (L), FASTA
>2D7T_2 anti polyhydroxybutyrate antibody Fv, light chain (chains L)
DIVMTQSPSSLSASVGDRVTITCRASQNINNYLHWYQHEPGKAPKLLIYAASNLQGGVTS
RFSGSGSGTDFTLTISTLQPEDFATYYCLQTHAYPLTFGGGTKVDIKRAAHHHHHH

Primary citation

A human antibody fragment with high affinity for the biodegradable polymer film. Watanabe, H., Tsumoto, K., Taguchi, S. et al. To be published.

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