2KJ3: Small s protein

High-resolution structure of the HET-s(218-289) prion in its amyloid form obtained by solid-state NMR. Determined by solid-state NMR. Released 2 Jun 2010.

Method: Solid-state NMR
Organism: Podospora anserina
Chains: 3
Atoms: 1,827
Mol. weight: 26 kDa
Released: 2 Jun 2010

Explore 2KJ3 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2KJ3 contains 1 α-helix and 18 β-strands across 3 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 1 helix, 5 β-strands

Element	Residues	Length	Sheet
α-helix	222-223	2
β-strand	226-234	9	1
β-strand	238-245	8	2
β-strand	261-270	10	1
β-strand	274-281	8	2
β-strand	291	1	3

Chain B: 0 helices, 7 β-strands

Element	Residues	Length	Sheet
β-strand	223	1	4
β-strand	225-234	10	1
β-strand	238-245	8	2
β-strand	258	1	4
β-strand	261-270	10	1
β-strand	274-281	8	2
β-strand	290	1	3

Chain C: 0 helices, 6 β-strands

Element	Residues	Length	Sheet
β-strand	223	1	5
β-strand	225-234	10	1
β-strand	238-245	8	2
β-strand	258	1	5
β-strand	262-270	9	1
β-strand	274-281	8	2

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Small s protein	A, B, C	protein	79	Podospora anserina	Q03689 (AlphaFold model)

Sequence of entity 1 (A, B, C), FASTA

>2KJ3_1 Small s protein (chains A, B, C)
MKIDAIVGRNSAKDIRTEERARVQLGNVVTAAALHGGIRISDQTTNSVETVVGKGESRVL
IGNEYGGKGFWDNHHHHHH

Primary citation

Atomic-Resolution Three-Dimensional Structure of HET-s(218-289) Amyloid Fibrils by Solid-State NMR Spectroscopy. Van Melckebeke, H., Wasmer, C., Lange, A. et al. J Am Chem Soc (2010) 132:13765-13775. DOI 10.1021/ja104213j · PubMed

Other PDB entries of the same protein (UniProt Q03689 (AlphaFold model), which also has an AlphaFold model), best resolution first:

2WVQ 2.0 Å, Structure of the HET-s N-terminal domain. Mutant D23A, P33H
2WVN 2.62 Å, Structure of the HET-s N-terminal domain
2LBU HADDOCK calculated model of Congo red bound to the HET-s amyloid
2MUS HADDOCK calculated model of LIN5001 bound to the HET-s amyloid
2RNM Structure of The HET-s(218-289) prion in its amyloid form obtained by solid-state NMR

Browse structure collections

About this viewer

MolViewer shows 2KJ3 directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.