2L08: Regulator of nonsense transcripts 3A

Solution NMR Structure of Nonsense mRNA reducing factor 3A from H. Sapiens, Northeast Structural Genomics Consortium Target HR4714B. Determined by solution NMR. Released 11 Aug 2010.

Method
Solution NMR
Organism
Homo sapiens
Chains
1
Atoms
824
Mol. weight
11.6 kDa
Released
11 Aug 2010

Explore 2L08 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2L08 contains 3 α-helices and 6 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 3 helices, 6 β-strands

ElementResiduesLengthSheet
α-helix6-83
β-strand12-1541
α-helix23-264
β-strand36-3831
β-strand57-6041
α-helix63-7210
β-strand76-7942
β-strand85-8842
β-strand89-9241

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Regulator of nonsense transcripts 3AAprotein97Homo sapiensQ9H1J1 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>2L08_1 Regulator of nonsense transcripts 3A (chains A)
MGHHHHHHSHMVVIRRLPPGLTKEQLEEQLRPLPAHDYFEFFAADLSLYPHLYSRAYINF
RNPDDILLFRDRFDGYIFLDSKGLEYPAVVEFAPFQK

Primary citation

Solution NMR Structure of Nonsense mRNA reducing factor 3A from H. Sapiens, Northeast Structural Genomics Consortium Target HR4714B. Mani, R., Mao, L., Ciccosanti, C. et al. To be published.

Other PDB entries of the same protein (UniProt Q9H1J1 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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