2PSN: Enolase1

Crystal structure of enolase1. Determined by X-ray diffraction at 2.2 Å resolution. Released 20 May 2008.

Method

X-ray diffraction

Resolution

2.2 Å

Organism

Homo sapiens

Chains

4

Atoms

13,815

Mol. weight

189.49 kDa

Ligands

PO4, MG

Released

20 May 2008

Explore 2PSN in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2PSN contains 95 α-helices and 81 β-strands across 4 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 24 helices, 20 β-strands

Molecules and chains

>2PSN_1 Alpha-enolase (chains A, B, C, D)
MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGK
GVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCK
AGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFRE
AMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKV
VIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDD
WGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLA
QANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSK
AKFAGRNFRNPLAK

Ligands and cofactors

Primary citation

Crystal Structure of Enolase1 alpha. Hyo, J.K., Seung, J.K., Sang, J.C. et al. To be published.

Related structures

Other PDB entries of the same protein (UniProt P06733 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 5NI9 1.33 Å, Crystal structure of HLA-DRB1*04:01 with the alpha-enolase peptide 326-340
• 5NIG 1.35 Å, Crystal structure of HLA-DRB1*04:01 with modified alpha-enolase peptide 326-340…
• 5OCK 1.6 Å, Crystal structure of ACPA E4 in complex with CEP1
• 5JLZ 1.99 Å, Crystal structure of HLA-DRB1*04:01 in complex with modified alpha-enolase peptide 26-40…
• 3B97 2.2 Å, Crystal Structure of human Enolase 1
• 8TRL 2.4 Å, T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4
• 5LAX 2.6 Å, Crystal structure of HLA_DRB1*04:01 in complex with alpha-enolase peptide 26-40
• 9X4F 2.7 Å, Crystal structure of tetrameric alpha-enolase with asymmetric flexible active sites
• 9A0U Docking model of HLA class I with HLA class II

Browse structure collections

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