2UYZ: Non-covalent complex between Ubc9 and SUMO1

Non-covalent complex between Ubc9 and SUMO1. Determined by X-ray diffraction at 1.4 Å resolution. Released 12 Jun 2007.

Method: X-ray diffraction
Resolution: 1.4 Å
Organisms: MUS MUSCULUS, HOMO SAPIENS
Chains: 2
Atoms: 2,539
Mol. weight: 27.27 kDa
Released: 12 Jun 2007

Explore 2UYZ in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

2UYZ contains 13 α-helices and 12 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 8 helices, 7 β-strands

Element	Residues	Length	Sheet
α-helix	4-18	15
β-strand	25-30	6	1
β-strand	36-46	11	1
α-helix	47-48	2
β-strand	57-63	7	1
α-helix	72-73	2
β-strand	74-77	4	1
β-strand	86	1	2
β-strand	91	1	1
β-strand	92	1	2
α-helix	93	1
α-helix	95-97	3
α-helix	109-121	13
α-helix	131-139	9
α-helix	141-154	14

Chain B: 5 helices, 5 β-strands

Element	Residues	Length	Sheet
β-strand	21-27	7	3
β-strand	33-39	7	3
α-helix	45-55	11
α-helix	59-61	3
β-strand	62-66	5	3
β-strand	69-70	2	3
α-helix	71-72	2
α-helix	77-80	4
β-strand	86-92	7	3
α-helix	93-94	2

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Sumo-conjugating enzyme UBC9	A	protein	158	MUS MUSCULUS	P63280 (AlphaFold model)
Small ubiquitin-related modifier 1	B	protein	79	HOMO SAPIENS	P63165 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>2UYZ_1 SUMO-CONJUGATING ENZYME UBC9 (chains A)
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKL
RMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVSLSILEEDKDWRPAITIKQILLGIQELL
NEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS

Sequence of entity 2 (B), FASTA

>2UYZ_2 SMALL UBIQUITIN-RELATED MODIFIER 1 (chains B)
MEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPK
ELGMEEEDVIEVYQEQTGG

Primary citation

Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation. Knipscheer, P., van Dijk, W.J., Olsen, J.V. et al. EMBO J (2007) 26:2797-2807. DOI 10.1038/sj.emboj.7601711 · PubMed

Other PDB entries of the same protein (UniProt P63280 (AlphaFold model), which also has an AlphaFold model), best resolution first:

1U9A 2.0 Å, Human ubiquitin-conjugating enzyme UBC9
1U9B 2.0 Å, Murine/human ubiquitin-conjugating enzyme UBC9
2VRR 2.22 Å, Structure of SUMO modified Ubc9

Browse structure collections

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