The crystal structure of Im2 in complex with colicin E9 DNase. Determined by X-ray diffraction at 1.78 Å resolution. Released 2 Jun 2010.
Explore 2WPT in 3D Show helices and sheets RCSB PDB PDBe
2WPT contains 14 α-helices and 15 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 7-9 | 3 | |
| β-strand | 11 | 1 | 1 |
| α-helix | 12-23 | 12 | |
| α-helix | 30-44 | 15 | |
| α-helix | 51-54 | 4 | |
| α-helix | 64-77 | 14 | |
| β-strand | 84 | 1 | 1 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 9-10 | 2 | 2 |
| β-strand | 12 | 1 | 3 |
| β-strand | 16 | 1 | 4 |
| α-helix | 22-26 | 5 | |
| β-strand | 32-33 | 2 | 5 |
| α-helix | 34 | 1 | |
| β-strand | 35 | 1 | 4 |
| α-helix | 36-42 | 7 | |
| β-strand | 46-47 | 2 | 2 |
| α-helix | 50-63 | 14 | |
| α-helix | 65-68 | 4 | |
| α-helix | 73-80 | 8 | |
| α-helix | 83-85 | 3 | |
| β-strand | 86 | 1 | 6 |
| α-helix | 87-88 | 2 | |
| α-helix | 89-91 | 3 | |
| β-strand | 93 | 1 | 7 |
| β-strand | 96 | 1 | 7 |
| β-strand | 98 | 1 | 6 |
| β-strand | 100-103 | 4 | 5 |
| β-strand | 115 | 1 | 3 |
| β-strand | 119-122 | 4 | 5 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Colicin-E2 immunity protein | A | protein | 86 | ESCHERICHIA COLI | P04482 (AlphaFold model) |
| Colicin-E9 | B | protein | 134 | ESCHERICHIA COLI | P09883 (AlphaFold model) |
>2WPT_1 COLICIN-E2 IMMUNITY PROTEIN (chains A) MELKHSISDYTEAEFLEFVKKIARAEGATECDDNKLVREFERLTEHPDGSDLIYYPRDDR EDSPEGIVKEIKEWRAANGKSGFKQG
>2WPT_2 COLICIN-E9 (chains B) MESKRNKPGKATGKGKPVGDKWLDDAGKDSGAPIPDRIADKLRDKEFKSFDDFRKAVWEE VSKDPELSKNLNPSNKSSVSKGYSPFTPKNQQVGCRKVYELHHDKPISQGGEVYDMDNIR VTTPKRHIDIHRGK
The Structural and Energetic Basis for High Selectivity in a High-Affinity Protein-Protein Interaction. Meenan, N.A., Sharma, A., Fleishman, S.J. et al. Proc Natl Acad Sci U S A (2010) 107:10080. DOI 10.1073/PNAS.0910756107 · PubMed
Other PDB entries of the same protein (UniProt P04482 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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