4A64: N-terminal domain of human Cul4B

Crystal structure of the N-terminal domain of human Cul4B at 2.57A resolution. Determined by X-ray diffraction at 2.57 Å resolution. Released 29 Feb 2012.

Method
X-ray diffraction
Resolution
2.57 Å
Organism
HOMO SAPIENS
Chains
4
Atoms
11,395
Mol. weight
168.24 kDa
Released
29 Feb 2012

Explore 4A64 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

4A64 contains 90 α-helices and 0 β-strands across 4 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 23 helices, 0 β-strands

ElementResiduesLengthSheet
α-helix187-1904
α-helix197-21014
α-helix219-23214
α-helix235-25218
α-helix255-2584
α-helix264-28825
α-helix290-2945
α-helix304-3052
α-helix306-3149
α-helix315-3195
α-helix322-34019
α-helix347-35913
α-helix363-3686
α-helix369-38921
α-helix392-41221
α-helix416-4183
α-helix419-43012
α-helix432-4343
α-helix435-44814
α-helix452-46211
α-helix468-48922
α-helix497-51519
α-helix520-53112
Chain B: 23 helices, 0 β-strands
ElementResiduesLengthSheet
α-helix187-1904
α-helix197-21014
α-helix219-23214
α-helix235-25218
α-helix255-2584
α-helix264-28825
α-helix290-2945
α-helix304-3052
α-helix306-3149
α-helix315-3195
α-helix322-34019
α-helix347-35913
α-helix363-3686
α-helix369-38921
α-helix392-41322
α-helix416-4183
α-helix419-43012
α-helix432-4343
α-helix435-44814
α-helix452-46211
α-helix468-48922
α-helix497-51519
α-helix520-53112
Chain C: 22 helices, 0 β-strands
ElementResiduesLengthSheet
α-helix197-21115
α-helix219-23012
α-helix238-25215
α-helix255-2584
α-helix264-28825
α-helix290-2978
α-helix304-3052
α-helix306-3149
α-helix315-3195
α-helix322-34019
α-helix347-35913
α-helix363-3686
α-helix369-38921
α-helix392-41322
α-helix416-4183
α-helix419-43012
α-helix432-4343
α-helix435-44814
α-helix452-46211
α-helix468-48922
α-helix497-51418
α-helix520-53011
Chain D: 22 helices, 0 β-strands
ElementResiduesLengthSheet
α-helix197-21014
α-helix219-22911
α-helix238-25215
α-helix255-2584
α-helix264-28825
α-helix290-2989
α-helix304-3052
α-helix306-3149
α-helix315-3195
α-helix322-34019
α-helix347-35913
α-helix363-3686
α-helix369-38921
α-helix392-41322
α-helix416-4183
α-helix419-43012
α-helix432-4343
α-helix435-44814
α-helix452-46211
α-helix468-48821
α-helix501-51414
α-helix520-53011

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Cullin-4BA, B, C, Dprotein354HOMO SAPIENSQ13620 (AlphaFold model)
Sequence of entity 1 (A, B, C, D), FASTA
>4A64_1 CULLIN-4B (chains A, B, C, D)
SMPKLPENYTDETWQKLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQI
CEDHIKAQIHQFREDSLDSVLFLKKIDRCWQNHCRQMIMIRSIFLFLDRTYVLQNSMLPS
IWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDLQIYQD
SFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIAT
VEKQLLGEHLTAILQKGLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFGS
TIVINPEKDKTMRQELDDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKRPN

Primary citation

Crystal Structure of the N-Terminal Domain of Human Cul4B at 2.57A Resolution. Vollmar, M., Ayinampudi, V., Cooper, C. et al. To be published.

Other PDB entries of the same protein (UniProt Q13620 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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