4BEH: Human ribosomal protein P1.P2 heterodimer

Solution structure of human ribosomal protein P1.P2 heterodimer. Determined by solution NMR. Released 14 Aug 2013.

Method: Solution NMR
Organism: HOMO SAPIENS
Chains: 2
Atoms: 1,631
Mol. weight: 23.27 kDa
Released: 14 Aug 2013

Explore 4BEH in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

4BEH contains 8 α-helices and 4 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 4 helices, 0 β-strands

Element	Residues	Length
α-helix	4-16	13
α-helix	25-35	11
α-helix	42-50	9
α-helix	57-60	4

Chain B: 4 helices, 4 β-strands

Element	Residues	Length	Sheet
β-strand	201	1	1
β-strand	202-203	2	2
α-helix	204-212	9
α-helix	220-230	11
α-helix	236-246	11
α-helix	251-256	6
β-strand	263	1	2
β-strand	266	1	1

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
60S acidic ribosomal protein P1	A	protein	114	HOMO SAPIENS	P05386 (AlphaFold model)
60S acidic ribosomal protein P2	B	protein	116	HOMO SAPIENS	P05387 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>4BEH_1 60S ACIDIC RIBOSOMAL PROTEIN P1 (chains A)
MASVSELACIYSALILHDDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANVNIGSLI
CNVGAGGPAPAAGAAPAGGPAPSTAAAPAEEKKVEAKKEESEESDDDMGFGLFD

Sequence of entity 2 (B), FASTA

>4BEH_2 60S ACIDIC RIBOSOMAL PROTEIN P2 (chains B)
AMRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGKNIEDVIAQGI
GKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD

Primary citation

Solution Structure of Human P1P2 Heterodimer Provides Insights Into the Role of Eukaryotic Stalk in Recruiting the Ribosome-Inactivating Protein Trichosanthin to the Ribosome. Lee, K.M., Yusa, K., Chu, L.O. et al. Nucleic Acids Res (2013) 41:8776. DOI 10.1093/NAR/GKT636 · PubMed

Other PDB entries of the same protein (UniProt P05386 (AlphaFold model), which also has an AlphaFold model), best resolution first:

4V6X 5.0 Å, Structure of the human 80S ribosome
2LBF Solution structure of the dimerization domain of human ribosomal protein P1/P2 heterodimer

Browse structure collections

About this viewer

MolViewer shows 4BEH directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.