4CBF: Envelope protein E

Near-atomic resolution cryo-EM structure of Dengue serotype 4 virus. Determined by electron microscopy at 4.1 Å resolution. Released 6 Nov 2013.

Method

Electron microscopy

Resolution

4.1 Å

Organisms

DENGUE VIRUS 2, DENGUE VIRUS 4

Chains

6

Atoms

1,707

Mol. weight

186.74 kDa

Released

6 Nov 2013

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Molecules and chains

>4CBF_1 ENVELOPE PROTEIN E (chains A, C, E)
MRCVGVGNRDFVEGVSGGAWVDLVLEHGGCVTTMAQGKPTLDFELTKTTAKEVALLRTYC
IEASISNITTATRCPTQGEPYLKEEQDQQYICRRDVVDRGWGNGCGLFGKGGVVTCAKFL
CSGKITGNLVQIENLEYTVAVTVHNGDTHAVGNDTSSHGVTATITPRSPSVEVKLPDYGE
LTLDCEPRSGIDFNEMILMKMKKKTWLVHKQWFLDLPLPWTAGADTSEVHWNHKERMVTF
KVPHAKRQDVTVLGSQEGAMHSALAGATEVDSGDGNHMFAGHLKCKVRMEKLRIKGMSYT
MCSGKFSIDKEMAETQHGTTVVKVKYEGAGAPCKVPIEIRDVNKEKVVGRIISSTPFAEN
TNSVTNIELEPPFGDSYIVIGVGESALTLHWFRKGSSIGKMFESTYRGAKRMAILGETAW
DFGSVGGLFTSLGKAVHQVFGSVYTTMFGGVSWMVRILIGFLVLWIGTNSRNTSMAMTCI
AVGGITLFLGFTVQA

>4CBF_2 M PROTEIN (chains B, D, F)
SVALTPHSGMGLETRAETWMSSEGAWKHAQRVESWILRNPGFALLAGFMAYMIGQTGIQR
TVFFVLMMLVAPSY

Primary citation

Near-Atomic Resolution Cryo-Electron Microscopic Structure of Dengue Serotype 4 Virus. Kostyuchenko, V.A., Chew, P.L., Ng, T. et al. J Virol (2014) 88:477. DOI 10.1128/JVI.02641-13 · PubMed

Related structures

Other PDB entries of the same protein (UniProt P14340), best resolution first:

• 6FLC 2.0 Å, 2C8 Fab bound to EDIII of DenV 2
• 6IZY 2.11 Å, The RNA-dependent RNA polymerase domain of dengue 2 NS5
• 6FLB 2.2 Å, 3H5 Fab bound to EDIII of DenV 2 Xtal form 2
• 6IZX 2.43 Å, The RNA-dependent RNA polymerase domain of dengue 2 NS5, bound with RK-0404678
• 6FLA 2.9 Å, 3H5 Fab bound to EDIII of DenV 2 Xtal form 1
• 7V3F 3.1 Å, DENV2_NGC_Fab_C10 28degree (1Fab:3E)
• 7V3G 3.3 Å, DENV2_NGC_Fab_C10 28degrees (2Fab:3E)
• 7CTH 3.5 Å, Cryo-EM structure of dengue virus serotype 2 in complex with the scFv fragment of the…
• 3J27 3.6 Å, CryoEM structure of Dengue virus
• 3J2P 3.6 Å, CryoEM structure of Dengue virus envelope protein heterotetramer
• 7V3H 3.6 Å, DENV2_NGC_Fab_C10 28degrees (3Fab:3E)
• 9DTT 3.6 Å, Cryo-EM structure of DENV2 NS5 in complex with Stem Loop A (SLA)

Browse structure collections

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