Structure of the AB18.1 TCR. Determined by X-ray diffraction at 3.01 Å resolution. Released 18 Dec 2013.
Explore 4NDM in 3D Show helices and sheets RCSB PDB PDBe
4NDM contains 11 α-helices and 40 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 10-15 | 6 | 1 |
| β-strand | 20-24 | 5 | 2 |
| β-strand | 33-39 | 7 | 1 |
| β-strand | 46-52 | 7 | 1 |
| β-strand | 57-60 | 4 | 1 |
| α-helix | 61 | 1 | |
| α-helix | 64-65 | 2 | |
| β-strand | 69-72 | 4 | 2 |
| β-strand | 79-83 | 5 | 2 |
| α-helix | 88-90 | 3 | |
| β-strand | 92-99 | 8 | 1 |
| β-strand | 105-116 | 12 | 1 |
| α-helix | 119-121 | 3 | |
| β-strand | 123 | 1 | 3 |
| β-strand | 126-131 | 6 | 4 |
| α-helix | 132-133 | 2 | |
| α-helix | 134-139 | 6 | |
| β-strand | 142-152 | 11 | 4 |
| β-strand | 153 | 1 | 3 |
| β-strand | 157-163 | 7 | 5 |
| β-strand | 166-167 | 2 | 5 |
| β-strand | 172-174 | 3 | 4 |
| β-strand | 179-180 | 2 | 4 |
| β-strand | 190-199 | 10 | 4 |
| α-helix | 200-203 | 4 | |
| β-strand | 209-216 | 8 | 5 |
| β-strand | 219 | 1 | 6 |
| β-strand | 233 | 1 | 6 |
| β-strand | 235-242 | 8 | 5 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 3-5 | 3 | 7 |
| α-helix | 8-10 | 3 | |
| β-strand | 11-14 | 4 | 8 |
| β-strand | 19-26 | 8 | 7 |
| β-strand | 33-39 | 7 | 8 |
| β-strand | 45-52 | 8 | 8 |
| β-strand | 59-60 | 2 | 7 |
| β-strand | 63-68 | 6 | 7 |
| β-strand | 73-78 | 6 | 7 |
| α-helix | 83-85 | 3 | |
| β-strand | 87-95 | 9 | 8 |
| β-strand | 107-110 | 4 | 8 |
| β-strand | 114-119 | 6 | 8 |
| α-helix | 120-122 | 3 | |
| β-strand | 128-132 | 5 | 9 |
| β-strand | 133-134 | 2 | 4 |
| β-strand | 142-146 | 5 | 9 |
| α-helix | 155-157 | 3 | |
| β-strand | 162-164 | 3 | 9 |
| β-strand | 168-172 | 5 | 9 |
| β-strand | 177-186 | 10 | 9 |
| β-strand | 207 | 1 | 9 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| T-cell gamma protein,T-cell receptor beta-2 chain C region | A | protein | 258 | Homo sapiens | A2NUW5 (AlphaFold model), K7N5M4 (AlphaFold model) |
| Human nkt tcr alpha chain | B | protein | 235 | Homo sapiens | K7N5M3 (AlphaFold model), Q6PJ56 (AlphaFold model) |
>4NDM_1 T-cell gamma protein,T-cell receptor beta-2 chain C region (chains A) ADPSSNLEGGTKSVTRPTRSSAEITCDLTVINAFYIHWYLHQEGKAPQRLLYYDVSNSKD VLESGLSPGKYYTHTPRRWSWILILRNLIENDSGVYYCATWDRNNKKLFGSGTTLVVTED LKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQP LKEQPALNDSRYALSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVS AEAWGRADSRGGLEVLFQ
>4NDM_2 Human nkt tcr alpha chain (chains B) ADLSQQGEEDPAQKVTQAQSSVSMPVRKAVTLNCLYETSWWSYYIFWYKQLPSKEMIFLI RQGSDEQNAKSGRYSVNFKKAAKSVALTISALQLEDSAKYFCALGDQILYWGLSHTDKLI FGKGTRVTVEPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCV LDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESSSRGGLEVLFQ
Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells. Luoma, A.M., Castro, C.D., Mayassi, T. et al. Immunity (2013) 39:1032-1042. DOI 10.1016/j.immuni.2013.11.001 · PubMed
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