The carboxy-terminal domain of Erb1 is a seven-bladed beta-propeller that binds RNA. Determined by X-ray diffraction at 1.6 Å resolution. Released 29 Apr 2015.
Explore 4U7A in 3D Show helices and sheets RCSB PDB PDBe
4U7A contains 7 α-helices and 31 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 419-422 | 4 | |
| β-strand | 428-433 | 6 | 1 |
| β-strand | 440-445 | 6 | 2 |
| β-strand | 451-456 | 6 | 2 |
| β-strand | 460-465 | 6 | 2 |
| β-strand | 471-476 | 6 | 2 |
| β-strand | 488-493 | 6 | 3 |
| β-strand | 502-506 | 5 | 3 |
| β-strand | 509-513 | 5 | 3 |
| α-helix | 520-531 | 12 | |
| β-strand | 573-576 | 4 | 3 |
| α-helix | 577-579 | 3 | |
| α-helix | 580-583 | 4 | |
| β-strand | 587-593 | 7 | 3 |
| β-strand | 599-602 | 4 | 4 |
| β-strand | 608-612 | 5 | 4 |
| α-helix | 617-619 | 3 | |
| β-strand | 621-625 | 5 | 4 |
| α-helix | 626-628 | 3 | |
| β-strand | 630-632 | 3 | 4 |
| β-strand | 642-647 | 6 | 5 |
| β-strand | 653-658 | 6 | 5 |
| β-strand | 662-666 | 5 | 5 |
| β-strand | 671-676 | 6 | 5 |
| β-strand | 683-688 | 6 | 6 |
| β-strand | 694-699 | 6 | 6 |
| β-strand | 704-708 | 5 | 6 |
| β-strand | 717-719 | 3 | 6 |
| β-strand | 726-731 | 6 | 7 |
| β-strand | 737-742 | 6 | 7 |
| β-strand | 747-753 | 7 | 7 |
| β-strand | 763-770 | 8 | 7 |
| α-helix | 773-775 | 3 | |
| β-strand | 776 | 1 | 8 |
| β-strand | 779 | 1 | 8 |
| β-strand | 781-786 | 6 | 1 |
| β-strand | 793-797 | 5 | 1 |
| β-strand | 802-806 | 5 | 1 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Ribosome biogenesis protein ERB1 | A | protein | 826 | Saccharomyces cerevisiae | Q04660 (AlphaFold model) |
>4U7A_1 Ribosome biogenesis protein ERB1 (chains A) AHHHHHHSAALEVLFQGPGMMAKNNKTTEAKMSKKRAASEESDVEEDEDKLLSVDGLIDA EASESDEDDDEYESAVEEKESSSDKEAQDDSDDDSDAELNKLLAEEEGDGEEDYDSSEFS DDTTSLTDRLSGVKLQTIVDPNIYSKYADGSDRIIKPEINPVYDSDDSDAETQNTIGNIP LSAYDEMPHIGYDINGKRIMRPAKGSALDQLLDSIELPEGWTGLLDKNSGSSLNLTKEEL ELISKIQRNEQTDDSINPYEPLIDWFTRHEEVMPLTAVPEPKRRFVPSKNEAKRVMKIVR AIREGRIIPPKKLKEMKEKEKIENYQYDLWGDSTETNDHVMHLRAPKLPPPTNEESYNPP EEYLLSPEEKEAWENTEYSERERNFIPQKYSALRKVPGYGESIRERFERSLDLYLAPRVR KNKLNIDPNSLIPELPSPKDLRPFPIRCSTIYAGHKGKVRTLSIDPSGLWLATGSDDGTV RVWEILTGREVYRTTLIDDEENPDYHIECIEWNPDANNGILAVAVGENIHLIVPPIFGYD IENNGKTKIEDGFGYDTFGTVKKSNLEVNENGDGDEDGENESAKNAVKKQVAQWNKPSQK QLEKDICITISCKKTVKKLSWHRKGDYFVTVQPDSGNTSVLIHQVSKHLTQSPFKKSKGI IMDAKFHPFKPQLFVCSQRYVRIYDLSQQILVKKLLPGARWLSKIDIHPRGDNLIASSFD KRVLWHDLDLASTPYKTLRYHEKAVRSVNFHKKLPLFSSAADDGTIHVFHATVYDDMMKN PMIVPLKKLTGHKVINSLGVLDAIWHPREAWLFSAGADNTARLWTT
| ID | Name | Formula | Copies |
|---|---|---|---|
| EOH | Ethanol | C2 H6 O | 1 |
Water and common crystallization additives (GOL, EDO) are not listed.
The Carboxy-Terminal Domain of Erb1 Is a Seven-Bladed -Propeller that Binds RNA. Wegrecki, M., Neira, J.L., Bravo, J. PLoS One (2015) 10:e0123463-e0123463. DOI 10.1371/journal.pone.0123463 · PubMed
Other PDB entries of the same protein (UniProt Q04660 (AlphaFold model), which also has an AlphaFold model), best resolution first:
MolViewer shows 4U7A directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.