4V49: 30S ribosomal protein S2
Crystal Structure of a Streptomycin Dependent Ribosome from E. Coli 70S Ribosome. Determined by X-ray diffraction at 8.7 Å resolution. Released 9 Jul 2014.
- Method
- X-ray diffraction
- Resolution
- 8.7 Å
- Organism
- Escherichia coli
- Chains
- 56
- Atoms
- 122,017
- Mol. weight
- 2193.23 kDa
- Released
- 9 Jul 2014
Explore 4V49 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
4V49 contains 103 α-helices and 108 β-strands across 19 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain AB: 11 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-14 | 3 | |
| α-helix | 26-31 | 6 | |
| β-strand | 32-36 | 5 | 1 |
| β-strand | 39-42 | 4 | 1 |
| α-helix | 44-62 | 19 | |
| β-strand | 69-71 | 3 | 2 |
| α-helix | 75-86 | 12 | |
| β-strand | 92-93 | 2 | 2 |
| α-helix | 105-121 | 17 | |
| α-helix | 126-128 | 3 | |
| α-helix | 134-148 | 15 | |
| β-strand | 162-164 | 3 | 2 |
| α-helix | 171-180 | 10 | |
| β-strand | 184-188 | 5 | 2 |
| α-helix | 194-196 | 3 | |
| β-strand | 199-202 | 4 | 2 |
| α-helix | 208-224 | 17 | |
| α-helix | 236-239 | 4 | |
Chain AC: 8 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 7-11 | 5 | |
| α-helix | 29-46 | 18 | |
| β-strand | 52-56 | 5 | 3 |
| β-strand | 67-70 | 4 | 3 |
| α-helix | 73-77 | 5 | |
| α-helix | 83-92 | 10 | |
| β-strand | 102-105 | 4 | 3 |
| α-helix | 109-111 | 3 | |
| α-helix | 113-126 | 14 | |
| α-helix | 130-142 | 13 | |
| β-strand | 148-153 | 6 | 4 |
| α-helix | 157-159 | 3 | |
| β-strand | 166 | 1 | 4 |
| β-strand | 169-170 | 2 | 4 |
| β-strand | 182-187 | 6 | 4 |
| β-strand | 198-203 | 6 | 4 |
Chain AD: 15 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-14 | 6 | |
| α-helix | 39 | 1 | |
| α-helix | 47-49 | 3 | |
| α-helix | 53-67 | 15 | |
| α-helix | 72-84 | 13 | |
| α-helix | 89-98 | 10 | |
| β-strand | 100 | 1 | 5 |
| α-helix | 101-107 | 7 | |
| α-helix | 114-122 | 9 | |
| β-strand | 126 | 1 | 6 |
| β-strand | 127 | 1 | 7 |
| β-strand | 132 | 1 | 7 |
| β-strand | 139 | 1 | 5 |
| β-strand | 145 | 1 | 8 |
| α-helix | 147 | 1 | |
| β-strand | 148 | 1 | 6 |
| α-helix | 149 | 1 | |
| α-helix | 150-153 | 4 | |
| α-helix | 156-164 | 9 | |
| β-strand | 176-177 | 2 | 9 |
| β-strand | 182-183 | 2 | 9 |
| β-strand | 184 | 1 | 8 |
| α-helix | 188-190 | 3 | |
| α-helix | 191-193 | 3 | |
| α-helix | 200-206 | 7 | |
Chain AE: 4 helices, 12 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 7-14 | 8 | 10 |
| β-strand | 19-20 | 2 | 11 |
| β-strand | 23-24 | 2 | 11 |
| β-strand | 28-35 | 8 | 10 |
| β-strand | 40-48 | 9 | 10 |
| α-helix | 51-63 | 13 | |
| β-strand | 66-68 | 3 | 10 |
| β-strand | 72 | 1 | 12 |
| β-strand | 75 | 1 | 12 |
| β-strand | 80-84 | 5 | 13 |
| β-strand | 87-93 | 7 | 13 |
| β-strand | 100-101 | 2 | 13 |
| α-helix | 104-112 | 9 | |
| β-strand | 118-124 | 7 | 13 |
| α-helix | 128-141 | 14 | |
| α-helix | 145-151 | 7 | |
Chain AF: 2 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 2-3 | 2 | 14 |
| β-strand | 4-10 | 7 | 15 |
| α-helix | 16-33 | 18 | |
| β-strand | 39-52 | 14 | 15 |
| β-strand | 55-64 | 10 | 15 |
| β-strand | 66-67 | 2 | 14 |
| α-helix | 69-81 | 13 | |
| β-strand | 85-92 | 8 | 15 |
| β-strand | 98-99 | 2 | 16 |
Chain AG: 8 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 8-15 | 8 | |
| α-helix | 21-30 | 10 | |
| α-helix | 36-52 | 17 | |
| α-helix | 58-69 | 12 | |
| β-strand | 73-76 | 4 | 17 |
| β-strand | 79 | 1 | 18 |
| β-strand | 84 | 1 | 18 |
| β-strand | 87-90 | 4 | 17 |
| α-helix | 93-108 | 16 | |
| α-helix | 116-129 | 14 | |
| α-helix | 133-144 | 12 | |
| α-helix | 151-154 | 4 | |
Chain AH: 5 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 5-18 | 14 | |
| β-strand | 25-27 | 3 | 19 |
| α-helix | 30-41 | 12 | |
| β-strand | 47-53 | 7 | 19 |
| β-strand | 56-62 | 7 | 19 |
| β-strand | 65 | 1 | 20 |
| α-helix | 75-77 | 3 | |
| β-strand | 78 | 1 | 20 |
| β-strand | 83-85 | 3 | 21 |
| β-strand | 94-95 | 2 | 21 |
| α-helix | 103-106 | 4 | |
| β-strand | 109-114 | 6 | 21 |
| β-strand | 117-120 | 4 | 21 |
| α-helix | 121-126 | 6 | |
| β-strand | 131-137 | 7 | 21 |
Chain AI: 8 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 4-6 | 3 | 22 |
| β-strand | 9 | 1 | 22 |
| β-strand | 14-19 | 6 | 22 |
| β-strand | 26-28 | 3 | 22 |
| β-strand | 32 | 1 | 22 |
| α-helix | 33-36 | 4 | |
| α-helix | 43-45 | 3 | |
| α-helix | 48-52 | 5 | |
| β-strand | 61-66 | 6 | 22 |
| α-helix | 70-88 | 19 | |
| α-helix | 90-92 | 3 | |
| α-helix | 93-96 | 4 | |
| α-helix | 109-111 | 3 | |
| α-helix | 122-124 | 3 | |
11 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 16S ribosomal RNA | AA | RNA | 1527 | Escherichia coli | |
| tRNA-Phe | AV, AW | RNA | 76 | Escherichia coli | |
| mRNA | AU | RNA | 18 | | |
| 30S ribosomal protein S2 | AB | protein | 234 | Escherichia coli | |
| 30S ribosomal protein S3 | AC | protein | 206 | Escherichia coli | |
| 30S ribosomal protein S4 | AD | protein | 208 | Escherichia coli | |
| 30S ribosomal protein S5 | AE | protein | 150 | Escherichia coli | |
| 30S ribosomal protein S6 | AF | protein | 101 | Escherichia coli | |
| 30S ribosomal protein S7 | AG | protein | 155 | Escherichia coli | |
| 30S ribosomal protein S8 | AH | protein | 138 | Escherichia coli | |
| 30S ribosomal protein S9 | AI | protein | 127 | Escherichia coli | |
| 30S ribosomal protein S10 | AJ | protein | 98 | Escherichia coli | |
43 more molecules are not listed.
Sequence of entity 1 (AA), FASTA
>4V49_1 16S RIBOSOMAL RNA (chains AA)
UGGAGAGUUUGAUCCUGGCUCAGGGUGAACGCUGGCGGCGUGCCUAAGACAUGCAAGUCG
UGCGGAUACGCGCGGCCCCUUGGGGCCGUGCGUCAGCGGCGGACGGGUGAGUAACGCGUG
GGUGACCUACCCGGAAGAGGGGGACAACCCGGGGAAACUCGGGCUAAUCCCCCAUGUGGA
CGCAAGUCCAAAGGGGGAAGCCUUCGGGUCCCCCGCUUCCGGAUGGGCCCGCGUCCCAUC
AGCUAGUUGGUGGGGUAAUGGCCCACCAAGGCGACGACGGGUAGCCGGUCUGAGAGGAUG
GCCGGCCACAGGGGCACUGAGACACGGGCCCCACUCCUACGGGAGGCAGCAGUUAGGAAU
CUUCCGCAAUGGGCGCAAGCCUGACGGAGCGACGCCGCUUGGAGGAAGAAGCCCUUCGGG
GUGUAAACUCCUGAACCCGGGACGAAACCAGGGCCACUCAUACUGGCUCUGACUGACGGU
ACCGGGGUAAUAGCGCCGGCCAACUCCGUGCCAGCAGCCGCGGUAAUACGGAGGGCGCGA
GCGUUACCCGGAUUCACUGGGCGUAAAGGGCGUGUAGGCGGCCUGGGGCGUCCCAUGUGA
AAGACCACGGCUCAACCGUGGGGGAGCGUGGGAUACGCUCAGGCUAGACGGUGGGAGAGG
GUGGUGGAAUUCCCGGAGUAGCGGUGAAAUGCGCAGAUACCGGGAGGAACGCCGAUGGCG
AAGGCAGCCACCUGGUCCACCCGUGACGCUGAGGCGCGAAAGCGUGGGGAGCAAACCGGA
UUAGAUACCCGGGUAGUCCACGCCCUAAACGAUGCGCGCUAGGUCUCUGGCGGCUCAACC
GCUGGGGGCCGAAGCUAACGCGUUAAGCGCGCCGCCUGGGGAGUACGGCCGCAAGGCUGA
AACUCAAAGGAAUUGACGGGGGCCCGCACAAGCGGUGGAGCAUGUGGUUUAAUUCGAAGC
AACGCGAAGAACCUUACCAGGCCUUGACAUGCUAGGGAACCCGGGUGAAAGCCUGGGGUG
CCUUCGGGAGCCCUAGCACAGGUGCUGCAUGGCCGUCGUCAGCUCGUGCCGUGAGGUGUU
GGGUUAAGUCCCGCAACGAGCGCAACCCCCGCCGUUAGUUGCCAGCGGUUCGGCCGGGCA
CUCUAACGGGACUGCCCGCGAAAGCGGGAGGAAGGAGGGGACGACGUCUGGUCAGCAUGG
CCCUUACGGCCUGGGCGACACACGUGCUACAAUGCCCACUACAAAGCGAUGCCACCCGGC
AACGGGGAGCUAAUCGCAAAAAGGUGGGCCCAGUUCGGAUUGGGGUCUGCAACCCGACCC
CAUGAAGCCGGAAUCGCUAGUAAUCGCGGAUCAGCCAUGCCGCGGUGAAUACGUUCCCGG
GCCUUGUACACACCGCCCGUCACGCCAUGGGAGCGGGCUCUACCCGAAGUCGCCGGGUAA
CCUACGGGAAGCAGGCGCCGAGGGUAGGGCCCGUGACUGGGGCGAAGUCGUAACAAGGUA
GCUGUACCGGAAGGUGCGGCUGGAUCA
Sequence of entity 2 (AV, AW), FASTA
>4V49_2 tRNA-Phe (chains AV, AW)
GCGGAUUUAGCUCAGUUGGGAGAGCGCCAGACUGAAGAUCUGGAGGUCCUGUGUUCGAUC
CACAGAAUUCGCACCA
Sequence of entity 3 (AU), FASTA
>4V49_3 mRNA (chains AU)
AUGUUCAAACGUAAUAAU
Sequence of entity 4 (AB), FASTA
>4V49_4 30S ribosomal protein S2 (chains AB)
VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFRFIEDLAMRGG
TILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFKTISQRVHRLEELEALFASPE
IEERPKKEQVRLKHELERLQKYLSGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIA
LADTDSDPDLVDYIIPGNDDAIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ
Sequence of entity 5 (AC), FASTA
>4V49_5 30S ribosomal protein S3 (chains AC)
GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAGLARVDIERAA
DNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVALNVQEVQNPNLSAPLVAQRVA
EQIERRFAVRRAIKQAVQRVMESGAKGAKVIVSGRIGGAEQARTEWAAQGRVPLHTLRAN
IDYGFALARTTYGVLGVKAYIFLGEV
Sequence of entity 6 (AD), FASTA
>4V49_6 30S ribosomal protein S4 (chains AD)
GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREK
QKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLV
RHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGM
KGKFLRLPDREDLALPVNEQLVIEFYSR
Sequence of entity 7 (AE), FASTA
>4V49_7 30S ribosomal protein S5 (chains AE)
DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARR
NMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELG
SRNPINIAYATMEALRQLRTKADVERLRKG
Sequence of entity 8 (AF), FASTA
>4V49_8 30S ribosomal protein S6 (chains AF)
MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYF
LWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA
Sequence of entity 9 (AG), FASTA
>4V49_9 30S ribosomal protein S7 (chains AG)
ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQEKTGQEPLKV
FKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLALRWLVQAANQRPERRAAVRIA
HELMDAAEGKGGAVKKKEDVERMAEANRAYAHYRW
Sequence of entity 10 (AH), FASTA
>4V49_10 30S ribosomal protein S8 (chains AH)
MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLR
VYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLT
DREARKLGVGGELICEVW
Sequence of entity 11 (AI), FASTA
>4V49_11 30S ribosomal protein S9 (chains AI)
EQYYGTGRRKEAVARVFLRPGNGKVTVNGQDFNEYFQGLVRAVAALEPLRAVDALGRFDA
YITVRGGGKSGQIDAIKLGIARALVQYNPDYRAKLKPLGFLTRDARVVERKKYGKHKARR
APQYSKR
Sequence of entity 12 (AJ), FASTA
>4V49_12 30S ribosomal protein S10 (chains AJ)
KIRIKLRGFDHKTLDASAQKIVEAARRSGAQVSGPIPLPTRVRRFTVIRGPFKHKDSREH
FELRTHNRLVDIINPNRKTIEQLMTLDLPTGVEIEIKT
Primary citation
X-ray Crystal Structures of the WT and a Hyper-Accurate Ribosome From Escherichia Coli. Vila-Sanjurjo, A., Ridgeway, W.K., Seymaner, V. et al. Proc Natl Acad Sci U S A (2003) 100:8682-8687. DOI 10.1073/pnas.1133380100 · PubMed
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