Crystal Structure of Myo7b N-MyTH4-FERM-SH3 in complex with Anks4b CEN. Determined by X-ray diffraction at 3.41 Å resolution. Released 16 Mar 2016.
Explore 5F3Y in 3D Show helices and sheets RCSB PDB PDBe
5F3Y contains 24 α-helices and 25 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 973-980 | 8 | |
| α-helix | 1006-1021 | 16 | |
| α-helix | 1068-1081 | 14 | |
| α-helix | 1085-1097 | 13 | |
| α-helix | 1103-1119 | 17 | |
| α-helix | 1121-1123 | 3 | |
| α-helix | 1127-1135 | 9 | |
| α-helix | 1142-1155 | 14 | |
| α-helix | 1161-1163 | 3 | |
| α-helix | 1164-1172 | 9 | |
| β-strand | 1176-1182 | 7 | 1 |
| β-strand | 1187-1192 | 6 | 1 |
| β-strand | 1197 | 1 | 2 |
| α-helix | 1198-1209 | 12 | |
| β-strand | 1217-1223 | 7 | 1 |
| β-strand | 1226-1229 | 4 | 1 |
| β-strand | 1236 | 1 | 2 |
| α-helix | 1237-1251 | 15 | |
| β-strand | 1260-1266 | 7 | 1 |
| α-helix | 1279-1295 | 17 | |
| α-helix | 1303-1317 | 15 | |
| α-helix | 1324-1334 | 11 | |
| α-helix | 1337-1340 | 4 | |
| α-helix | 1345-1359 | 15 | |
| α-helix | 1368-1382 | 15 | |
| β-strand | 1389-1393 | 5 | 3 |
| β-strand | 1394-1397 | 4 | 4 |
| β-strand | 1406-1410 | 5 | 3 |
| β-strand | 1415-1418 | 4 | 3 |
| β-strand | 1424-1428 | 5 | 3 |
| α-helix | 1430-1432 | 3 | |
| β-strand | 1433-1438 | 6 | 4 |
| β-strand | 1447-1452 | 6 | 4 |
| β-strand | 1456-1460 | 5 | 4 |
| α-helix | 1464-1481 | 18 | |
| β-strand | 1484-1487 | 4 | 5 |
| β-strand | 1491 | 1 | 6 |
| β-strand | 1499 | 1 | 5 |
| α-helix | 1500-1501 | 2 | |
| β-strand | 1502 | 1 | 6 |
| β-strand | 1507-1509 | 3 | 5 |
| β-strand | 1522-1527 | 6 | 5 |
| β-strand | 1533-1537 | 5 | 5 |
| α-helix | 1538-1540 | 3 | |
| β-strand | 1541-1543 | 3 | 5 |
| α-helix | 1549-1551 | 3 | |
| α-helix | 1552-1557 | 6 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 266-267 | 2 | 1 |
| β-strand | 271-272 | 2 | 1 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Unconventional myosin-VIIb | A | protein | 621 | Mus musculus | Q99MZ6 (AlphaFold model) |
| Ankyrin repeat and SAM domain-containing protein 4B | B | protein | 102 | Mus musculus | Q8K3X6 (AlphaFold model) |
>5F3Y_1 Unconventional myosin-VIIb (chains A) GSEFEEEVDSLAEYTFPKFAVTYFQKSASHTHIQKPLRYPLLYHENDTDHSAALDVWIII LRFMGDLPEPVVYGRNSLTGSSVMRQIHDKLGKDSVTQHNRSSQVASQLNFGEEAFKFDG PISDRPMSNLEKVHFIVGYAIMRPGLRDEIYCQICKQLSENYKTSSRARGWILLSLCLGC FPPSERFMKYLLNFISQGPPSYGPFCAERLQRTFANGVRAEPPTWLELQAVKSKKHIPIQ VILATGRSLTISVDSASTSREICQHVAQKQGLRDNLGFSLQVAVYDKFWSLGSGCDHLMD AVAQCEQLARERGESQRQAPWRIYFRKEFFTPWHDSQEDPVSTELIYHQVLRGVWSGEYN FEKEEELVELLARHCYVQLGATVKSNAVQELLPSCVPSKLYRTKSPEKWASLVTAAHAKA QYTQSKATPLAVREQTVEAARLLWPLLFSRLFEVTTLSGPRLPKTQLVLAINWKGMYFLD QKERTLLGLSFAEVMGLVANRDAPGGKKLLLATLQEEYEFVSPSSVAIAEMVALFLGGLK ERSVFAMALQDRRATDDITLLPFKKGDLLILTKKQGLLASENWALGQNDRTGKTGLVPTA CLYTIPSVTKPSTQLLSLLAM
>5F3Y_2 Ankyrin repeat and SAM domain-containing protein 4B (chains B) GSVEEDDDVQHESILNRPGLGSIVFSRNRVLDFEDISDSKRELGFKMPSELFQRQGAAGT VEEEEEEEEEEEEEKREANGTAGDLPWDEEEVEWEEDAVDAT
Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex. Li, J., He, Y., Lu, Q. et al. Dev Cell (2016) 36:179-189. DOI 10.1016/j.devcel.2015.12.020 · PubMed
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