5OWU: Kap95:Nup1 complex

Kap95:Nup1 complex. Determined by X-ray diffraction at 2.0 Å resolution. Released 25 Oct 2017.

Method
X-ray diffraction
Resolution
2.0 Å
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Chains
2
Atoms
7,640
Mol. weight
208.56 kDa
Released
25 Oct 2017

Explore 5OWU in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

5OWU contains 65 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 64 helices, 0 β-strands

ElementResiduesLengthSheet
α-helix3-1513
α-helix19-3517
α-helix37-4812
α-helix55-6713
α-helix74-8714
α-helix90-10415
α-helix109-12618
α-helix127-1293
α-helix133-14210
α-helix149-16517
α-helix174-1763
α-helix177-18812
α-helix195-20814
α-helix209-2113
α-helix213-2164
α-helix219-23315
α-helix238-25518
α-helix256-2583
α-helix260-2623
α-helix263-2675
α-helix268-2747
α-helix280-30627
α-helix317-33216
α-helix347-36216
α-helix363-3664
α-helix367-37711
α-helix383-39513
α-helix402-41817
α-helix419-4213
α-helix425-44218
α-helix443-4453
α-helix452-46312
α-helix467-48418
α-helix491-4955
α-helix496-50712
α-helix513-5153
α-helix516-53015
α-helix533-5353
α-helix536-55318
α-helix558-5603
α-helix563-58624
α-helix588-5903
α-helix592-5943
α-helix595-60713
α-helix611-6133
α-helix615-62915
α-helix630-6367
α-helix637-64913
α-helix655-66915
α-helix671-6744
α-helix675-68915
α-helix698-71316
α-helix714-7174
α-helix718-73215
α-helix734-7363
α-helix741-76424
α-helix769-7724
α-helix773-7753
α-helix776-78813
α-helix790-7934
α-helix796-81217
α-helix819-8213
α-helix825-83612
α-helix842-86019
Chain B: 1 helix, 0 β-strands
ElementResiduesLengthSheet
α-helix1004-10074

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Importin subunit beta-1Aprotein861Saccharomyces cerevisiae (strain ATCC 204508 / S288c)Q06142 (AlphaFold model)
Nucleoporin NUP1Bprotein1076Saccharomyces cerevisiae (strain ATCC 204508 / S288c)P20676 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>5OWU_1 Importin subunit beta-1 (chains A)
MSTAEFAQLLENSILSPDQNIRLTSETQLKKLSNDNFLQFAGLSSQVLIDENTKLEGRIL
AALTLKNELVSKDSVKTQQFAQRWITQVSPEAKNQIKTNALTALVSIEPRIANAAAQLIA
AIADIELPHGAWPELMKIMVDNTGAEQPENVKRASLLALGYMCESADPQSQALVSSSNNI
LIAIVQGAQSTETSKAVRLAALNALADSLIFIKNNMEREGERNYLMQVVCEATQAEDIEV
QAAAFGCLCKIMSLYYTFMKPYMEQALYALTIATMKSPNDKVASMTVEFWSTICEEEIDI
AYELAQFPQSPLQSYNFALSSIKDVVPNLLNLLTRQNEDPEDDDWNVSMSAGACLQLFAQ
NCGNHILEPVLEFVEQNITADNWRNREAAVMAFGSIMDGPDKVQRTYYVHQALPSILNLM
NDQSLQVKETTAWCIGRIADSVAESIDPQQHLPGVVQACLIGLQDHPKVATNCSWTIINL
VEQLAEATPSPIYNFYPALVDGLIGAANRIDNEFNARASAFSALTTMVEYATDTVAETSA
SISTFVMDKLGQTMSVDENQLTLEDAQSLQELQSNILTVLAAVIRKSPSSVEPVADMLMG
LFFRLLEKKDSAFIEDDVFYAISALAASLGKGFEKYLETFSPYLLKALNQVDSPVSITAV
GFIADISNSLEEDFRRYSDAMMNVLAQMISNPNARRELKPAVLSVFGDIASNIGADFIPY
LNDIMALCVAAQNTKPENGTLEALDYQIKVLEAVLDAYVGIVAGLHDKPEALFPYVGTIF
QFIAQVAEDPQLYSEDATSRAAVGLIGDIAAMFPDGSIKQFYGQDWVIDYIKRTRSGQLF
SQATKDTARWAREQQKRQLSL
Sequence of entity 2 (B), FASTA
>5OWU_2 Nucleoporin NUP1 (chains B)
MSSNTSSVMSSPRVEKRSFSSTLKSFFTNPNKKRPSSKKVFSSNLSYANHLEESDVEDTL
HVNKRKRVSGTSQHSDSLTQNNNNAPIIIYGTENTERPPLLPILPIQRLRLLREKQRVRN
MRELGLIQSTEFPSITSSVILGSQSKSDEGGSYLCTSSTPSPIKNGSCTRQLAGKSGEDT
NVGLPILKSLKNRSNRKRFHSQSKGTVWSANFEYDLSEYDAIQKKDNKDKEGNAGGDQKT
SENRNNIKSSISNGNLATGPNLTSEIEDLRADINSNRLSNPQKNLLLKGPASTVAKTAPI
QESFVPNSERSGTPTLKKNIEPKKDKESIVLPTVGFDFIKDNETPSKKTSPKATSSAGAV
FKSSVEMGKTDKSTKTAEAPTLSFNFSQKANKTKAVDNTVPSTTLFNFGGKSDTVTSASQ
PFKFGKTSEKSENHTESDAPPKSTAPIFSFGKQEENGDEGDDENEPKRKRRLPVSEDTNT
KPLFDFGKTGDQKETKKGESEKDASGKPSFVFGASDKQAEGTPLFTFGKKADVTSNIDSS
AQFTFGKAATAKETHTKPSETPATIVKKPTFTFGQSTSENKISEGSAKPTFSFSKSEEER
KSSPISNEAAKPSFSFPGKPVDVQAPTDDKTLKPTFSFTEPAQKDSSVVSEPKKPSFTFA
SSKTSQPKPLFSFGKSDAAKEPPGSNTSFSFTKPPANETDKRPTPPSFTFGGSTTNNTTT
TSTKPSFSFGAPESMKSTASTAAANTEKLSNGFSFTKFNHNKEKSNSPTSFFDGSASSTP
IPVLGKPTDATGNTTSKSAFSFGTANTNGTNASANSTSFSFNAPATGNGTTTTSNTSGTN
IAGTFNVGKPDQSIASGNTNGAGSAFGFSSSGTAATGAASNQSSFNFGNNGAGGLNPFTS
ATSSTNANAGLFNKPPSTNAQNVNVPSAFNFTGNNSTPGGGSVFNMNGNTNANTVFAGSN
NQPHQSQTPSFNTNSSFTPSTVPNINFSGLNGGITNTATNALRPSDIFGANAASGSNSNV
TNPSSIFGGAGGVPTTSFGQPQSAPNQMGMGTNNGMSMGGGVMANRKIARMRHSKR

Primary citation

Structural basis for the high-affinity binding of nucleoporin Nup1p to the Saccharomyces cerevisiae importin-beta homologue, Kap95p. Liu, S.M., Stewart, M. J Mol Biol (2005) 349:515-525. DOI 10.1016/j.jmb.2005.04.003 · PubMed

Other PDB entries of the same protein (UniProt Q06142 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

About this viewer

MolViewer shows 5OWU directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.