5VCL: Qdm peptide

Structure of the Qdm peptide bound to Qa-1a. Determined by X-ray diffraction at 2.05 Å resolution. Released 25 Oct 2017.

Method
X-ray diffraction
Resolution
2.05 Å
Organism
Mus musculus
Chains
3
Atoms
3,309
Mol. weight
45.67 kDa
Released
25 Oct 2017

Explore 5VCL in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

5VCL contains 12 α-helices and 29 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 10 helices, 19 β-strands

ElementResiduesLengthSheet
β-strand3-12101
α-helix201
β-strand21-2881
β-strand31-3771
β-strand46-4721
α-helix50-545
α-helix57-8529
β-strand94-103101
β-strand109-118101
β-strand121-12661
β-strand133-13531
α-helix138-14912
α-helix152-16110
α-helix163-17412
α-helix176-1794
β-strand18312
α-helix184-1852
β-strand186-19383
β-strand198-208113
β-strand20912
β-strand214-21964
β-strand222-22324
β-strand229-23023
α-helix231-2333
β-strand234-23523
β-strand241-250103
α-helix254-2563
β-strand257-26264
β-strand270-27234
Chain B: 2 helices, 10 β-strands
ElementResiduesLengthSheet
β-strand315
α-helix4-52
β-strand6-1166
β-strand21-30106
β-strand3115
β-strand36-4167
β-strand44-4527
α-helix461
β-strand50-5676
β-strand62-7096
β-strand78-8367
β-strand91-9447

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
H2-T23 proteinAprotein278Mus musculusQ31153 (AlphaFold model)
Beta-2-microglobulinBprotein99Mus musculusP01887 (AlphaFold model)
Qdm peptidePprotein9Mus musculusP01897 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>5VCL_1 H2-T23 protein (chains A)
MSSHSLRYFHTAMSRPGLGEPRFIVVGYVDDTQFVSFDSDSENPKMEPRARWMEQEGPEY
WERETWKARDMGRNFRVNLRTLLGYYNQSKDESHTLQWMYGCDVGPDGRLLRGYCQEAYD
GQDYISLNEDLRSWTATDFASQISKHKSEMVDEAHQQRAYLQGPCVEWLHTYLRLGNKTL
KRSDPPKAHVTHHPRSEDYVTLRCWALGFYPADITLTWQLNGEELTQDMEFVETRPAGDG
NFQKWASVVVPLGKEQNYTCHVEHEGLPEPLTLRWEPP
Sequence of entity 2 (B), FASTA
>5VCL_2 Beta-2-microglobulin (chains B)
IQKTPQIQVYSRHPPENGKPNILNCYVTQFHPPHIEIQMLKNGKKIPKVEMSDMSFSKDW
SFYILAHTEFTPTETDTYACRVKHASMAEPKTVYWDRDM
Sequence of entity 3 (P), FASTA
>5VCL_3 Qdm peptide (chains P)
AMAPRTLLL

Primary citation

Crystal structure of Qa-1a with bound Qa-1 determinant modifier peptide. Ying, G., Wang, J., Kumar, V. et al. PLoS One (2017) 12:e0182296-e0182296. DOI 10.1371/journal.pone.0182296 · PubMed

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