Crystal structures of human SALM5. Determined by X-ray diffraction at 2.8 Å resolution. Released 24 Jan 2018.
Explore 5XNQ in 3D Show helices and sheets RCSB PDB PDBe
5XNQ contains 10 α-helices and 20 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 16-19 | 4 | |
| β-strand | 25-29 | 5 | 1 |
| β-strand | 32-36 | 5 | 1 |
| β-strand | 55-57 | 3 | 1 |
| β-strand | 65-66 | 2 | 2 |
| β-strand | 79-81 | 3 | 1 |
| β-strand | 89-90 | 2 | 2 |
| β-strand | 103-105 | 3 | 1 |
| β-strand | 113-114 | 2 | 3 |
| β-strand | 127-129 | 3 | 1 |
| β-strand | 137-138 | 2 | 3 |
| β-strand | 151-153 | 3 | 1 |
| α-helix | 164-167 | 4 | |
| β-strand | 175-177 | 3 | 1 |
| β-strand | 199-201 | 3 | 1 |
| α-helix | 214-218 | 5 | |
| β-strand | 222 | 1 | 4 |
| β-strand | 229 | 1 | 4 |
| α-helix | 230-231 | 2 | |
| β-strand | 234-236 | 3 | 1 |
| β-strand | 242-243 | 2 | 5 |
| α-helix | 246-248 | 3 | |
| α-helix | 249-253 | 5 | |
| β-strand | 262 | 1 | 6 |
| β-strand | 263-265 | 3 | 5 |
| α-helix | 267-269 | 3 | |
| β-strand | 273 | 1 | 6 |
| α-helix | 274-276 | 3 | |
| α-helix | 279-281 | 3 | |
| α-helix | 284-286 | 3 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Leucine-rich repeat and fibronectin type-III domain-containing protein 5 | A | protein | 371 | Homo sapiens | Q96NI6 (AlphaFold model) |
>5XNQ_1 Leucine-rich repeat and fibronectin type-III domain-containing protein 5 (chains A) PGDPQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFAN MTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNN QLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSH LHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRR LSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGD PEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLH IIAAAHHHHHH
Water and common crystallization additives (NA, CL, SO4) are not listed.
Structural basis of SALM5-induced PTP delta dimerization for synaptic differentiation. Lin, Z., Liu, J., Ding, H. et al. Nat Commun (2018) 9:268-268. DOI 10.1038/s41467-017-02414-2 · PubMed
Other PDB entries of the same protein (UniProt Q96NI6 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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