F-actin of cardiac thin filament in high-calcium state. Determined by electron microscopy at 3.4 Å resolution. Released 15 Jan 2020.
Explore 6KLN in 3D Show helices and sheets RCSB PDB PDBe
6KLN contains 84 α-helices and 76 β-strands across 4 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 8-12 | 5 | 1 |
| β-strand | 16-21 | 6 | 1 |
| β-strand | 29-32 | 4 | 1 |
| β-strand | 35-38 | 4 | 2 |
| β-strand | 53-54 | 2 | 2 |
| α-helix | 57-60 | 4 | |
| β-strand | 65-68 | 4 | 2 |
| β-strand | 71-72 | 2 | 3 |
| β-strand | 75-76 | 2 | 3 |
| α-helix | 79-87 | 9 | |
| α-helix | 88-94 | 7 | |
| α-helix | 98-100 | 3 | |
| β-strand | 103-107 | 5 | 1 |
| α-helix | 113-125 | 13 | |
| β-strand | 131-136 | 6 | 1 |
| α-helix | 137-143 | 7 | |
| β-strand | 150-154 | 5 | 4 |
| β-strand | 160-165 | 6 | 4 |
| β-strand | 170 | 1 | 4 |
| α-helix | 172-174 | 3 | |
| β-strand | 176-178 | 3 | 4 |
| α-helix | 182-192 | 11 | |
| α-helix | 194-196 | 3 | |
| α-helix | 206-216 | 11 | |
| α-helix | 223-229 | 7 | |
| β-strand | 238-241 | 4 | 5 |
| β-strand | 247-250 | 4 | 5 |
| α-helix | 253-256 | 4 | |
| α-helix | 258-262 | 5 | |
| α-helix | 276-282 | 7 | |
| α-helix | 290-294 | 5 | |
| β-strand | 297-300 | 4 | 4 |
| α-helix | 303-305 | 3 | |
| α-helix | 309-317 | 9 | |
| β-strand | 329-330 | 2 | 4 |
| α-helix | 335-337 | 3 | |
| α-helix | 338-346 | 9 | |
| β-strand | 357-358 | 2 | 1 |
| α-helix | 359-363 | 5 | |
| α-helix | 367-369 | 3 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Actin, alpha skeletal muscle | A, B, C, D | protein | 375 | Mus musculus | P68134 (AlphaFold model) |
>6KLN_1 Actin, alpha skeletal muscle (chains A, B, C, D) DEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQS KRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMT QIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDL AGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSY ELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMS GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQ EYDEAGPSIVHRKCF
Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin. Oda, T., Yanagisawa, H., Wakabayashi, T. J Struct Biol (2020) 209:107450-107450. DOI 10.1016/j.jsb.2020.107450 · PubMed
Other PDB entries of the same protein (UniProt P68134 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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