Structure of CCDC50 and LC3B complex. Determined by X-ray diffraction at 1.41 Å resolution. Released 30 Sept 2020.
Explore 6LAN in 3D Show helices and sheets RCSB PDB PDBe
6LAN contains 7 α-helices and 7 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 2-3 | 2 | |
| α-helix | 7-10 | 4 | |
| α-helix | 13-26 | 14 | |
| β-strand | 30-37 | 8 | 1 |
| α-helix | 45-47 | 3 | |
| β-strand | 51-55 | 5 | 1 |
| β-strand | 59 | 1 | 2 |
| α-helix | 60-71 | 12 | |
| β-strand | 80-83 | 4 | 1 |
| β-strand | 87 | 1 | 1 |
| β-strand | 94 | 1 | 2 |
| α-helix | 95-102 | 8 | |
| β-strand | 109-114 | 6 | 1 |
| α-helix | 116-124 | 9 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Coiled-coil domain-containing protein 50,Microtubule-associated proteins 1A/1B light chain 3B | A | protein | 135 | Homo sapiens | Q8IVM0 (AlphaFold model), Q9GZQ8 (AlphaFold model) |
>6LAN_1 Coiled-coil domain-containing protein 50,Microtubule-associated proteins 1A/1B light chain 3B (chains A) GPDQEWYDAEIPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKT KFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLY MVYASQETFGMKLSV
A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection. Hou, P., Yang, K., Jia, P. et al. Cell Res (2021) 31:62-79. DOI 10.1038/s41422-020-0362-1 · PubMed
MolViewer shows 6LAN directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.