6ODG: Microtubule-associated protein tau

SVQIVY, Crystal Structure of a tau protein fragment. Determined by X-ray diffraction at 1.0 Å resolution. Released 2 Oct 2019.

Method
X-ray diffraction
Resolution
1.0 Å
Organism
Homo sapiens
Chains
2
Atoms
102
Mol. weight
1.42 kDa
Released
2 Oct 2019

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Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Microtubule-associated protein tauA, Bprotein6Homo sapiensP10636 (AlphaFold model)
Sequence of entity 1 (A, B), FASTA
>6ODG_1 Microtubule-associated protein tau (chains A, B)
SVQIVY

Primary citation

Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples. Seidler, P.M., Boyer, D.R., Murray, K.A. et al. J Biol Chem (2019) 294:16451-16464. DOI 10.1074/jbc.RA119.009688 · PubMed

Other PDB entries of the same protein (UniProt P10636 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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