6T9I: Transcription coactivator SAGA
cryo-EM structure of transcription coactivator SAGA. Determined by electron microscopy at 3.9 Å resolution. Released 29 Jan 2020.
- Method
- Electron microscopy
- Resolution
- 3.9 Å
- Organisms
- Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Saccharomyces cerevisiae S288C
- Chains
- 12
- Atoms
- 48,821
- Mol. weight
- 1080.34 kDa
- Released
- 29 Jan 2020
Explore 6T9I in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
6T9I contains 315 α-helices and 86 β-strands across 12 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain B: 10 helices, 12 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 124-129 | 6 | |
| β-strand | 138-141 | 4 | 1 |
| β-strand | 146-149 | 4 | 1 |
| β-strand | 172-173 | 2 | 1 |
| α-helix | 179-182 | 4 | |
| α-helix | 183-185 | 3 | |
| β-strand | 190 | 1 | 2 |
| α-helix | 196-202 | 7 | |
| α-helix | 204-206 | 3 | |
| β-strand | 207 | 1 | 3 |
| β-strand | 210 | 1 | 3 |
| β-strand | 211-217 | 7 | 1 |
| β-strand | 279-285 | 7 | 1 |
| β-strand | 286 | 1 | 2 |
| α-helix | 289-299 | 11 | |
| α-helix | 307-321 | 15 | |
| α-helix | 342-344 | 3 | |
| β-strand | 346 | 1 | 4 |
| β-strand | 349-350 | 2 | 5 |
| β-strand | 355-356 | 2 | 5 |
| α-helix | 404-412 | 9 | |
| α-helix | 476-487 | 12 | |
Chain C: 14 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 8-18 | 11 | |
| α-helix | 26-54 | 29 | |
| α-helix | 61-65 | 5 | |
| α-helix | 66-68 | 3 | |
| α-helix | 72-81 | 10 | |
| α-helix | 193-201 | 9 | |
| α-helix | 211-212 | 2 | |
| α-helix | 213-217 | 5 | |
| α-helix | 218-221 | 4 | |
| α-helix | 230-263 | 34 | |
| α-helix | 302-312 | 11 | |
| α-helix | 314-316 | 3 | |
| α-helix | 321-323 | 3 | |
| α-helix | 334-336 | 3 | |
Chain D: 18 helices, 29 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 57-70 | 14 | |
| α-helix | 75-86 | 12 | |
| α-helix | 88-89 | 2 | |
| α-helix | 104-106 | 3 | |
| α-helix | 152-164 | 13 | |
| α-helix | 171-189 | 19 | |
| α-helix | 194-203 | 10 | |
| α-helix | 209-212 | 4 | |
| α-helix | 215-218 | 4 | |
| α-helix | 225-228 | 4 | |
| α-helix | 232-239 | 8 | |
| α-helix | 241 | 1 | |
| β-strand | 242-245 | 4 | 6 |
| α-helix | 248-258 | 11 | |
| α-helix | 262-266 | 5 | |
| α-helix | 267-276 | 10 | |
| β-strand | 277-280 | 4 | 6 |
| α-helix | 432-443 | 12 | |
| α-helix | 450-452 | 3 | |
| α-helix | 454-455 | 2 | |
| β-strand | 456-462 | 7 | 7 |
| β-strand | 469-474 | 6 | 8 |
| β-strand | 480-485 | 6 | 8 |
| β-strand | 490-494 | 5 | 8 |
| β-strand | 518-521 | 4 | 8 |
| β-strand | 528-533 | 6 | 9 |
| β-strand | 539-544 | 6 | 9 |
| β-strand | 549-553 | 5 | 9 |
| β-strand | 558-563 | 6 | 9 |
| β-strand | 570-574 | 5 | 10 |
| β-strand | 583-586 | 4 | 10 |
| β-strand | 590-595 | 6 | 10 |
| β-strand | 598-606 | 9 | 10 |
| β-strand | 612-617 | 6 | 11 |
| β-strand | 623-628 | 6 | 11 |
| β-strand | 632-637 | 6 | 11 |
| β-strand | 643-648 | 6 | 11 |
| β-strand | 654-659 | 6 | 12 |
| β-strand | 665-670 | 6 | 12 |
| β-strand | 675-679 | 5 | 12 |
| β-strand | 685-689 | 5 | 12 |
| β-strand | 701-702 | 2 | 13 |
| β-strand | 708-712 | 5 | 13 |
| β-strand | 717-722 | 6 | 13 |
| β-strand | 768-773 | 6 | 13 |
| β-strand | 781-784 | 4 | 7 |
| β-strand | 789-795 | 7 | 7 |
Chain E: 22 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 18-24 | 7 | |
| α-helix | 31-58 | 28 | |
| α-helix | 66-69 | 4 | |
| α-helix | 71-75 | 5 | |
| α-helix | 78-80 | 3 | |
| β-strand | 100-101 | 2 | 14 |
| β-strand | 107-108 | 2 | 14 |
| β-strand | 115-116 | 2 | 15 |
| α-helix | 118-121 | 4 | |
| β-strand | 130 | 1 | 16 |
| α-helix | 131-132 | 2 | |
| β-strand | 134-138 | 5 | 7 |
| β-strand | 174 | 1 | 17 |
| β-strand | 211 | 1 | 17 |
| α-helix | 221-231 | 11 | |
| α-helix | 245-257 | 13 | |
| α-helix | 265-277 | 13 | |
| α-helix | 283-296 | 14 | |
| α-helix | 306-308 | 3 | |
| α-helix | 312-319 | 8 | |
| α-helix | 333-360 | 28 | |
| α-helix | 369-380 | 12 | |
| α-helix | 387-398 | 12 | |
| α-helix | 403-406 | 4 | |
| α-helix | 410-412 | 3 | |
| α-helix | 413-419 | 7 | |
| α-helix | 430-432 | 3 | |
| α-helix | 447-459 | 13 | |
| α-helix | 461-463 | 3 | |
Chain F: 8 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 31-42 | 12 | |
| α-helix | 51-77 | 27 | |
| α-helix | 90-98 | 9 | |
| β-strand | 108 | 1 | 18 |
| α-helix | 111-121 | 11 | |
| α-helix | 125-126 | 2 | |
| α-helix | 128-130 | 3 | |
| β-strand | 134 | 1 | 4 |
| α-helix | 136-139 | 4 | |
| α-helix | 140-142 | 3 | |
Chain G: 8 helices, 1 β-strand
| Element | Residues | Length | Sheet |
|---|
| α-helix | 71-73 | 3 | |
| α-helix | 74-81 | 8 | |
| α-helix | 90-100 | 11 | |
| α-helix | 107-134 | 28 | |
| α-helix | 137-144 | 8 | |
| α-helix | 146-154 | 9 | |
| α-helix | 169-176 | 8 | |
| β-strand | 182-183 | 2 | 15 |
| α-helix | 185-193 | 9 | |
Chain H: 12 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 184-187 | 4 | |
| α-helix | 192-198 | 7 | |
| α-helix | 212-220 | 9 | |
| β-strand | 223 | 1 | 19 |
| β-strand | 226 | 1 | 20 |
| α-helix | 230-238 | 9 | |
| α-helix | 244-255 | 12 | |
| α-helix | 260-263 | 4 | |
| α-helix | 269-283 | 15 | |
| β-strand | 289 | 1 | 21 |
| α-helix | 293-316 | 24 | |
| β-strand | 335-337 | 3 | 22 |
| α-helix | 341-348 | 8 | |
| α-helix | 350-352 | 3 | |
| α-helix | 357-364 | 8 | |
| α-helix | 408-417 | 10 | |
Chain I: 7 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 358-360 | 3 | |
| α-helix | 371-375 | 5 | |
| β-strand | 376 | 1 | 23 |
| β-strand | 402 | 1 | 23 |
| α-helix | 404-406 | 3 | |
| α-helix | 420-427 | 8 | |
| β-strand | 436-438 | 3 | 22 |
| α-helix | 440-467 | 28 | |
| β-strand | 473 | 1 | 21 |
| α-helix | 475-484 | 10 | |
| α-helix | 508-523 | 16 | |
4 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Transcription factor SPT20 | B | protein | 604 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | P50875 (AlphaFold model) |
| Protein SPT3 | C | protein | 337 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | P06844 (AlphaFold model) |
| Transcription initiation factor TFIID subunit 5 | D | protein | 798 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | P38129 (AlphaFold model) |
| Transcription initiation factor TFIID subunit 6 | E | protein | 516 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | P53040 (AlphaFold model) |
| Transcription initiation factor TFIID subunit 9 | F | protein | 157 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Q05027 |
| Transcription initiation factor TFIID subunit 10 | G | protein | 206 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Q12030 |
| Transcriptional coactivator HFI1/ADA1 | H | protein | 488 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Q12060 |
| Transcription initiation factor TFIID subunit 12 | I | protein | 539 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | Q03761 |
| Transcriptional activator SPT7 | K | protein | 1332 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | P35177 |
| SAGA-associated factor 73 | Q | protein | 657 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | P53165 |
| Transcription-associated protein 1 | T | protein | 3744 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | P38811 |
| unassigned sequence | U | protein | 155 | Saccharomyces cerevisiae S288C | |
Sequence of entity 1 (B), FASTA
>6T9I_1 Transcription factor SPT20 (chains B)
MSANSPTGNDPHVFGIPVNATPSNMGSPGSPVNVPPPMNPAVANVNHPVMRTNSNSNANE
GTRTLTREQIQQLQQRQRLLLQQRLLEQQRKQQALQNYEAQFYQMLMTLNKRPKRLYNFV
EDADSILKKYEQYLHSFEFHIYENNYKICAPANSRLQQQQKQPELTSDGLILTKNNETLK
EFLEYVARGRIPDAIMEVLRDCNIQFYEGNLILQVYDHTNTVDVTPKENKPNLNSSSSPS
NNNSTQDNSKIQQPSEPNSGVANTGANTANKKASFKRPRVYRTLLKPNDLTTYYDMMSYA
DNARFSDSIYQQFESEILTLTKRNLSLSVPLNPYEHRDMLEETAFSEPHWDSEKKSFIHE
HRAESTREGTKGVVGHIEERDEFPQHSSNYEQLMLIMNERTTTITNSTFAVSLTKNAMEI
ASSSSNGVRGASSSTSNSASNTRNNSLANGNQVALAAAAAAAAVGSTMGNDNNQFSRLKF
IEQWRINKEKRKQQALSANINPTPFNARISMTAPLTPQQQLLQRQQQALEQQQNGGAMKN
ANKRSGNNATSNNNNNNNNLDKPKVKRPRKNAKKSESGTPAPKKKRMTKKKQSASSTPSS
TTMS
Sequence of entity 2 (C), FASTA
>6T9I_2 Protein SPT3 (chains C)
MMDKHKYRVEIQQMMFVSGEINDPPVETTSLIEDIVRGQVIEILLQSNKTAHLRGSRSIL
PEDVIFLIRHDKAKVNRLRTYLSWKDLRKNAKDQDASAGVASGTGNPGAGGEDDLKKAGG
GEKDEKDGGNMMKVKKSQIKLPWELQFMFNEHPLENNDDNDDMDEDEREANIVTLKRLKM
ADDRTRNMTKEEYVHWSDCRQASFTFRKNKRFKDWSGISQLTEGKPHDDVIDILGFLTFE
IVCSLTETALKIKQREQVLQTQKDKSQQSSQDNTNFEFASSTLHRKKRLFDGPENVINPL
KPRHIEEAWRVLQTIDMRHRALTNFKGGRLSSKPIIM
Sequence of entity 3 (D), FASTA
>6T9I_3 Transcription initiation factor TFIID subunit 5 (chains D)
MSQKQSTNQNQNGTHQPQPVKNQRTNNAAGANSGQQPQQQSQGQSQQQGRSNGPFSASDL
NRIVLEYLNKKGYHRTEAMLRAESGRTLTPQNKQSPANTKTGKFPEQSSIPPNPGKTAKP
ISNPTNLSSKRDAEGGIVSSGRLEGLNAPENYIRAYSMLKNWVDSSLEIYKPELSYIMYP
IFIYLFLNLVAKNPVYARRFFDRFSPDFKDFHGSEINRLFSVNSIDHIKENEVASAFQSH
KYRITMSKTTLNLLLYFLNENESIGGSLIISVINQHLDPNIVESVTAREKLADGIKVLSD
SENGNGKQNLEMNSVPVKLGPFPKDEEFVKEIETELKIKDDQEKQLNQQTAGDNYSGANN
RTLLQEYKAMNNEKFKDNTGDDDKDKIKDKIAKDEEKKESELKVDGEKKDSNLSSPARDI
LPLPPKTALDLKLEIQKVKESRDAIKLDNLQLALPSVCMYTFQNTNKDMSCLDFSDDCRI
AAAGFQDSYIKIWSLDGSSLNNPNIALNNNDKDEDPTCKTLVGHSGTVYSTSFSPDNKYL
LSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCDHIY
PLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVC
PDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRV
WDLKKATTEPSAEPDEPFIGYLGDVTASINQDIKEYGRRRTVIPTSDLVASFYTKKTPVF
KVKFSRSNLALAGGAFRP
Sequence of entity 4 (E), FASTA
>6T9I_4 Transcription initiation factor TFIID subunit 6 (chains E)
MSTQQQSYTIWSPQDTVKDVAESLGLENINDDVLKALAMDVEYRILEIIEQAVKFKRHSK
RDVLTTDDVSKALRVLNVEPLYGYYDGSEVNKAVSFSKVNTSGGQSVYYLDEEEVDFDRL
INEPLPQVPRLPTFTTHWLAVEGVQPAIIQNPNLNDIRVSQPPFIRGAIVTALNDNSLQT
PVTSTTASASVTDTGASQHLSNVKPGQNTEVKPLVKHVLSKELQIYFNKVISTLTAKSQA
DEAAQHMKQAALTSLRTDSGLHQLVPYFIQFIAEQITQNLSDLQLLTTILEMIYSLLSNT
SIFLDPYIHSLMPSILTLLLAKKLGGSPKDDSPQEIHEFLERTNALRDFAASLLDYVLKK
FPQAYKSLKPRVTRTLLKTFLDINRVFGTYYGCLKGVSVLEGESIRFFLGNLNNWARLVF
NESGITLDNIEEHLNDDSNPTRTKFTKEETQILVDTVISALLVLKKDLPDLYEGKGEKVT
DEDKEKLLERCGVTIGFHILKRDDAKELISAIFFGE
Sequence of entity 5 (F), FASTA
>6T9I_5 Transcription initiation factor TFIID subunit 9 (chains F)
MNGGGKNVLNKNSVGSVSEVGPDSTQEETPRDVRLLHLLLASQSIHQYEDQVPLQLMDFA
HRYTQGVLKDALVYNDYAGSGNSAGSGLGVEDIRLAIAARTQYQFKPTAPKELMLQLAAE
RNKKALPQVMGTWGVRLPPEKYCLTAKEWDLEDPKSM
Sequence of entity 6 (G), FASTA
>6T9I_6 Transcription initiation factor TFIID subunit 10 (chains G)
MDFEEDYDAEFDDNQEGQLETPFPSVAGADDGDNDNDDSVAENMKKKQKREAVVDDGSEN
AFGIPEFTRKDKTLEEILEMMDSTPPIIPDAVIDYYLTKNGFNVADVRVKRLLALATQKF
VSDIAKDAYEYSRIRSSVAVSNANNSQARARQLLQGQQQPGVQQISQQQHQQNEKTTASK
VVLTVNDLSSAVAEYGLNIGRPDFYR
Sequence of entity 7 (H), FASTA
>6T9I_7 Transcriptional coactivator HFI1/ADA1 (chains H)
MSAIQSPAPKPLQPTYPAASPASTNAYMKPGLIGSPAVSNHTEPNNGNNETAEPQGPNQR
IDLGAMIEELTSLLGKESWTKYAQIISLFILGKLSRKELSNELELVFSPSAASLEKSNTN
HHHSLVRLHNQLLLGIFANSLRENPLGRNGNESSWGFGNGSNNPNNKLKRINKHNSQIEV
YKKIVMSLPLNDRNRLKMITKEAGKRGFIFCSVFQARLNNIPKIPIVTNPESLKRVKSNN
LKTPLEWSQDIMNGFNVPLASESHSLPDTDSFYLRMVGIAREHGLVGTVDARCVELISLA
LDQYLKNIIEFTIDTVRYRRKKYSDYYDLNESGLYKSVSEMAADKRDAKIKQLDDDKNED
ECADEAKSINNGNNSSKDDIGDISMSSITKAGEAVNEELHENRTISLTNEDIYDSLSIFP
NLVEPSGSYYALTNLGLVNDDELVDMKSNIDDLPDFLNEKPTFTPLDERNVGTRHELNWL
IKGILTED
Sequence of entity 8 (I), FASTA
>6T9I_8 Transcription initiation factor TFIID subunit 12 (chains I)
MSSNPENSGVNANNNTGTGNADAITGAQQNMVLQPRQLQEMAAKFRTLLTEARNVGETTP
RGKELMFQAAKIKQVYDALTLNRRRQQAAQAYNNTSNSNSSNPASIPTENVPNSSQQQQQ
QQQQTRNNSNKFSNMIKQVLTPEENQEYEKLWQNFQVRHTSIKEKETYLKQNIDRLEQEI
NKQTDEGPKQQLQEKKIELLNDWKVLKIEYTKLFNNYQNSKKTFYVECARHNPALHKFLQ
ESTQQQRVQQQRVQQQQQQQQQQQQQQQQQQQQQQQRQGQNQRKISSSNSTEIPSVTGPD
ALKSQQQQQNTITATNNPRGNVNTSQTEQSKAKVTNVNATASMLNNISSSKSAIFKQTEP
AIPISENISTKTPAPVAYRSNRPTITGGSAMNASALNTPATTKLPPYEMDTQRVMSKRKL
RELVKTVGIDEGDGETVIDGDVEELLLDLADDFVTNVTAFSCRLAKHRKSDNLEARDIQL
HLERNWNIRIPGYSADEIRSTRKWNPSQNYNQKLQSITSDKVAAAKNNGNNVASLNTKK
Sequence of entity 9 (K), FASTA
>6T9I_9 Transcriptional activator SPT7 (chains K)
MTERIPIKNYQRTNAKALLKLTEKLFNKNFFDLYLTSQQLVVLEYLLSISSEEDKLKAWD
YFLKGNIALNVEKSFPLTQEEEHHGAVSPAVDTRSDDVSSQTIKDNNNTNTNTSISNENH
VENEIEDKGDNAIANEDNFVNNDESDNVEEDLFKLDLEDLKQQISGTRFIGNLSLKIRYV
LWQCAIDYIYCDRNEFGDENDTEYTLLDVEEKEEEEIGKNEKPQNKEGISKFAEDEDYDD
EDENYDEDSTDVKNVDDPPKNLDSISSSNIEIDDERRLVLNISISKETLSKLKTNNVEEI
MGNWNKIYHSFEYDKETMIKRLKLEESDKMIEKGKKKRSRSDLEAATDEQDRENTNDEPD
TNQKLPTPEGSTFSDTGNKRPKQSNLDLTVNLGIENLSLKHLLSSIQQKKSQLGISDYEL
KHLIMDVRKNRSKWTSDERIGQEELYEACEKVVLELRNYTEHSTPFLNKVSKREAPNYHQ
IIKKSMDLNTVLKKLKSFQYDSKQEFVDDIMLIWKNCLTYNSDPSHFLRGHAIAMQKKSL
QLIRMIPNITIRNRADLEKEIEDMEKDKDYELDEEEEVAGSGRKGLNMGAHMLAKENGKV
SEKDSSKTVKDEAPTNDDKLTSVIPEGEKEKDKTASSTVTVHENVNKNEIKENGKNEEQD
MVEESSKTEDSSKDADAAKKDTEDGLQDKTAENKEAGENNEEEEDDDDEDEDEDMVDSQS
YLLEKDDDRDDLEISVWKTVTAKVRAEICLKRTEYFKNGKLNSDSEAFLKNPQRMKRFDQ
LFLEYKEQKALESYRQKIEQNSIMKNGFGTVLKQEDDDQLQFHNDHSLNGNEAFEKQPND
IELDDTRFLQEYDISNAIPDIVYEGVNTKTLDKMEDASVDRMLQNGINKQSRFLANKDLG
LTPKMNQNITLIQQIRHICHKISLIRMLQSPLSAQNSRSNPNAFLNNHIYNYTIIDDSLD
IDPVSQLPTHDYKNNRELIWKFMHKNISKVAMANGFETAHPSAINMLTEIAGDYLSNLIK
TLKLHHETNSLNRGTNVEMLQTTLLENGINRPDDLFSYVESEFGKKTKKLQDIKQKLESF
LRALLRPTLQELSERNFEDESQSFFTGDFASELTGEDFFGFRELGLEKEFGVLSSSVPLQ
LLTTQFQTVDGETKVQAKKIQPEESDSIVYKKITKGMLDAGSFWNTLLPLLQKDYERSKA
YIAKQSKSSANDKTSMTSTEDNSFALLEEDQFVSKKTATKARLPPTGKISTTYKKKPIAS
AFILPEEDLENDVKADPTTTVNAKVGAENDGDSSLFLRTPQPLDPLDMDDAFDDTNMGSN
SSFSLSLPRLNQ
Sequence of entity 10 (Q), FASTA
>6T9I_10 SAGA-associated factor 73 (chains Q)
MRSGDAEIKGIKPKVIEEYSLSQGSGPSNDSWKSLMSSAKDTPLQYDHMNRESLKKYFNP
NAQLIEDPLDKPIQYRVCEKCGKPLALTAIVDHLENHCAGASGKSSTDPRDESTRETIRN
GVESTGRNNNDDDNSNDNNNDDDDDDDNDDNEDDDDADDDDDNSNGANYKKNDSSFNPLK
RSTSMESANTPNMDTKRSKTGTPQTFSSSIKKQKKVKQRNPTEKHLIDFNKQCGVELPEG
GYCARSLTCKSHSMGAKRAVSGRSKPYDVLLADYHREHQTKIGAAAEKRAKQQELQKLQK
QIQKEQKKHTQQQKQGQRSKQRNVNGGKSAKNGGKSTVHNGNNINEIGHVNLTPEEETTQ
VLNGVSRSFPLPLESTVLSSVRYRTKYFRMREMFASSFSVKPGYTSPGYGAIHSRVGCLD
LDRTTDYKFRVRTPQPINHLTNQNLNPKQIQRLQQQRALQAQLLSQQQQQQQQQQQHHSP
QAQAQASTQQPTQGMVPNHFPGGATNSSFNANVSSKQIQQQQQQQQHKSQDTGLTPLEIQ
SQQQKLRQQQLQQQKFEAAASYLANATKLMQESNQDSHLSGTHNNNSSKNGNNNLMTMKA
SISSPNTSVNSIQSPPSVNSVNGSGQGVSTGINVSGNNGRIEVGIGNSVNPYNGRIN
Sequence of entity 11 (T), FASTA
>6T9I_11 Transcription-associated protein 1 (chains T)
MSLTEQIEQFASRFRDDDATLQSRYSTLSELYDIMELLNSPEDYHFFLQAVIPLLLNQLK
EVPISYDAHSPEQKLRNSMLDIFNRCLMNQTFQPYAMEVLEFLLSVLPKENEENGILCMK
VLTTLFKSFKSILQDKLDSFIRIIIQIYKNTPNLINQTFYEAGKAEQGDLDSPKEPQADE
LLDEFSKNDEEKDFPSKQSSTEPRFENSTSSNGLRSSMFSFKILSECPITMVTLYSSYKQ
LTSTSLPEFTPLIMNLLNIQIKQQQEAREQAESRGEHFTSISTEIINRPAYCDFILAQIK
ATSFLAYVFIRGYAPEFLQDYVNFVPDLIIRLLQDCPSELSSARKELLHATRHILSTNYK
KLFLPKLDYLFDERILIGNGFTMHETLRPLAYSTVADFIHNIRSELQLSEIEKTIKIYTG
YLLDESLALTVQIMSAKLLLNLVERILKLGKENPQEAPRAKKLLMIIIDSYMNRFKTLNR
QYDTIMKYYGRYETHKKEKAEKLKNSIQDNDKESEEFMRKVLEPSDDDHLMPQPKKEDIN
DSPDVEMTESDKVVKNDVEMFDIKNYAPILLLPTPTNDPIKDAFYLYRTLMSFLKTIIHD
LKVFNPPPNEYTVANPKLWASVSRVFSYEEVIVFKDLFHECIIGLKFFKDHNEKLSPETT
KKHFDISMPSLPVSATKDARELMDYLAFMFMQMDNATFNEIIEQELPFVYERMLEDSGLL
HVAQSFLTSEITSPNFAGILLRFLKGKLKDLGNVDFNTSNVLIRLFKLSFMSVNLFPNIN
EVVLLPHLNDLILNSLKYSTTAEEPLVYFYLIRTLFRSIGGGRFENLYRSIKPILQVLLQ
SLNQMILTARLPHERELYVELCITVPVRLSVLAPYLPFLMKPLVFALQQYPDLVSQGLRT
LELCIDNLTAEYFDPIIEPVIDDVSKALFNLLQPQPFNHAISHNVVRILGKLGGRNRQFL
KPPTDLTEKTELDIDAIADFKINGMPEDVPLSVTPGIQSALNILQSYKSDIHYRKSAYKY
LTCVLLLMTKSSAEFPTNYTELLKTAVNSIKLERIGIEKNFDLEPTVNKRDYSNQENLFL
RLLESVFYATSIKELKDDAMDLLNNLLDHFCLLQVNTTLLNKRNYNGTFNIDLKNPNFML
DSSLILDAIPFALSYYIPEVREVGVLAYKRIYEKSCLIYGEELALSHSFIPELAKQFIHL
CYDETYYNKRGGVLGIKVLIDNVKSSSVFLKKYQYNLANGLLFVLKDTQSEAPSAITDSA
EKLLIDLLSITFADVKEEDLGNKVLENTLTDIVCELSNANPKVRNACQKSLHTISNLTGI
PIVKLMDHSKQFLLSPIFAKPLRALPFTMQIGNVDAITFCLSLPNTFLTFNEELFRLLQE
SIVLADAEDESLSTNIQKTTEYSTSEQLVQLRIACIKLLAIALKNEEFATAQQGNIRIRI
LAVFFKTMLKTSPEIINTTYEALKGSLAENSKLPKELLQNGLKPLLMNLSDHQKLTVPGL
DALSKLLELLIAYFKVEIGRKLLDHLTAWCRVEVLDTLFGQDLAEQMPTKIIVSIINIFH
LLPPQADMFLNDLLLKVMLLERKLRLQLDSPFRTPLARYLNRFHNPVTEYFKKNMTLRQL
VLFMCNIVQRPEAKELAEDFEKELDNFYDFYISNIPKNQVRVVSFFTNMVDLFNTMVITN
GDEWLKKKGNMILKLKDMLNLTLKTIKENSFYIDHLQLNQSIAKFQALYLRFTELSERDQ
NPLLLDFIDFSFSNGIKASYSLKKFIFHNIIASSNKEKQNNFINDATLFVLSDKCLDARI
FVLKNVINSTLIYEVATSGSLKSYLVEDKKPKWLELLHNKIWKNSNAILAYDVLDHHDLF
RFELLQLSAIFIKADPEIIAEIKKDIIKFCWNFIKLEDTLIKQSAYLVTSYFISKFDFPI
KVVTQVFVALLRSSHVEARYLVKQSLDVLTPVLHERMNAAGTPDTWINWVKRVMVENSSS
QNNILYQFLISHPDLFFNSRDLFISNIIHHMNKITFMSNSNSDSHTLAIDLASLILYWEN
KTLEITNVNNTKTDSDGDVVMSDSKSDINPVEADTTAIIVDANNNSPISLHLREACTAFL
IRYVCASNHRAIETELGLRAINILSELISDKHWTNVNVKLVYFEKFLIFQDLDSENILYY
CMNALDVLYVFFKNKTKEWIMENLPTIQNLLEKCIKSDHHDVQEALQKVLQVIMKAIKAQ
GVSVIIEEESPGKTFIQMLTSVITQDLQETSSVTAGVTLAWVLFMNFPDNIVPLLTPLMK
TFSKLCKDHLSISQPKDAMALEEARITTKLLEKVLYILSLKVSLLGDSRRPFLSTVALLI
DHSMDQNFLRKIVNMSRSWIFNTEIFPTVKEKAAILTKMLAFEIRGEPSLSKLFYEIVLK
LFDQEHFNNTEITVRMEQPFLVGTRVEDIGIRKRFMTILDNSLERDIKERLYYVIRDQNW
EFIADYPWLNQALQLLYGSFNREKELSLKNIYCLSPPSILQEYLPENAEMVTEVNDLELS
NFVKGHIASMQGLCRIISSDFIDSLIEIFYQDPKAIHRAWVTLFPQVYKSIPKNEKYGFV
RSIITLLSKPYHTRQISSRTNVINMLLDSISKIESLELPPHLVKYLAISYNAWYQSINIL
ESIQSNTSIDNTKIIEANEDALLELYVNLQEEDMFYGLWRRRAKYTETNIGLSYEQIGLW
DKAQQLYEVAQVKARSGALPYSQSEYALWEDNWIQCAEKLQHWDVLTELAKHEGFTDLLL
ECGWRVADWNSDRDALEQSVKSVMDVPTPRRQMFKTFLALQNFAESRKGDQEVRKLCDEG
IQLSLIKWVSLPIRYTPAHKWLLHGFQQYMEFLEATQIYANLHTTTVQNLDSKAQEIKRI
LQAWRDRLPNTWDDVNMWNDLVTWRQHAFQVINNAYLPLIPALQQSNSNSNINTHAYRGY
HEIAWVINRFAHVARKHNMPDVCISQLARIYTLPNIEIQEAFLKLREQAKCHYQNMNELT
TGLDVISNTNLVYFGTVQKAEFFTLKGMFLSKLRAYEEANQAFATAVQIDLNLAKAWAQW
GFFNDRRLSEEPNNISFASNAISCYLQAAGLYKNSKIRELLCRILWLISIDDASGMLTNA
FDSFRGEIPVWYWITFIPQLLTSLSHKEANMVRHILIRIAKSYPQALHFQLRTTKEDFAV
IQRQTMAVMGDKPDTNDRNGRRQPWEYLQELNNILKTAYPLLALSLESLVAQINDRFKST
TDEDLFRLINVLLIDGTLNYNRLPFPRKNPKLPENTEKNLVKFSTTLLAPYIRPKFNADF
IDNKPDYETYIKRLRYWRRRLENKLDRASKKENLEVLCPHLSNFHHQKFEDIEIPGQYLL
NKDNNVHFIKIARFLPTVDFVRGTHSSYRRLMIRGHDGSVHSFAVQYPAVRHSRREERMF
QLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEIHNEFCKKKGF
DPDDIQDFMADKLNAAHDDALPAPDMTILKVEIFNSIQTMFVPSNVLKDHFTSLFTQFED
FWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVFTLEMLPSRFPYERVKPLL
KNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNELN
TYLALFIRDEIISWFSNLHRPIIENPQLREMVQTNVDLIIRKVAQLGHLNSTPTVTTQFI
LDCIGSAVSPRNLARTDVNFMPWF
Sequence of entity 12 (U), FASTA
>6T9I_12 unassigned sequence (chains U)
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Primary citation
Structure of the transcription coactivator SAGA. Wang, H., Dienemann, C., Stutzer, A. et al. Nature (2020) 577:717-720. DOI 10.1038/s41586-020-1933-5 · PubMed
Other PDB entries of the same protein (UniProt P50875 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 6T9K 3.3 Å, SAGA Core module
- 6T9J 3.4 Å, SAGA Tra1 module
Browse structure collections
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