6TRR: 16L protein

Name: PDB 6TRR: Structural insight into tanapoxvirus mediated inhibition of apoptosis
Published: 2020-06-03
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: apoptosis

Structural insight into tanapoxvirus mediated inhibition of apoptosis. Determined by X-ray diffraction at 2.12 Å resolution. Released 3 Jun 2020.

Method: X-ray diffraction
Resolution: 2.12 Å
Organisms: Yaba-like disease virus, Homo sapiens
Chains: 2
Atoms: 1,332
Mol. weight: 20.64 kDa
Released: 3 Jun 2020

Explore 6TRR in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6TRR contains 8 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 7 helices, 0 β-strands

Element	Residues	Length
α-helix	9-29	21
α-helix	33-52	20
α-helix	54-64	11
α-helix	71-87	17
α-helix	91-108	18
α-helix	115-129	15
α-helix	132-143	12

Chain B: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	154-172	19

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
16L protein	A	protein	152	Yaba-like disease virus	Q9DHU6 (AlphaFold model)
Apoptosis regulator BAX	B	protein	28	Homo sapiens	Q07812 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>6TRR_1 16L protein (chains A)
GPLGSMENSCNFNNSIKNVIVFYINEKALIEEKKMLSCYENKLLNLIKEDCENIMLKYKP
NLSYICSLLKVDDTSEENIKHIKDQIIESLENDNRPSVKLAIISLISMIVEMNGYKGKNI
PMSFLIEDIALKISENSEDLINFINIKNKQKS

Sequence of entity 2 (B), FASTA

>6TRR_2 Apoptosis regulator BAX (chains B)
VPQDASTKKLSECLKRIGDELDSNMELQ

Primary citation

Structural insight into tanapoxvirus-mediated inhibition of apoptosis. Suraweera, C.D., Anasir, M.I., Chugh, S. et al. FEBS J (2020) 287:3733-3750. DOI 10.1111/febs.15365 · PubMed

Other PDB entries of the same protein (UniProt Q9DHU6 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6TQP 1.85 Å, Structural insight into tanapoxvirus mediated inhibition of apoptosis
6TQQ 3.0 Å, Structural insight into tanapoxvirus mediated inhibition of apoptosis

Browse structure collections

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