6UZ7: K.lactis 80S ribosome with p/PE tRNA and eIF5B

Name: PDB 6UZ7: K.lactis 80S ribosome with p/PE tRNA and eIF5B
Published: 2020-01-15
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: ribosome

K.lactis 80S ribosome with p/PE tRNA and eIF5B. Determined by electron microscopy at 3.6 Å resolution. Released 15 Jan 2020.

Method: Electron microscopy
Resolution: 3.6 Å
Organisms: Kluyveromyces lactis, Saccharomyces cerevisiae
Chains: 83
Atoms: 211,187
Mol. weight: 4159.15 kDa
Ligands: GCP, ZN
Released: 15 Jan 2020

Explore 6UZ7 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6UZ7 contains 484 α-helices and 601 β-strands across 78 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain 1: 18 helices, 46 β-strands

Element	Residues	Length	Sheet
β-strand	373	1	39
β-strand	376	1	40
α-helix	384-390	7
β-strand	409-412	4	41
α-helix	417-420	4
α-helix	425-428	4
β-strand	437-440	4	41
β-strand	460	1	39
β-strand	464	1	40
β-strand	465	1	42
α-helix	477-483	7
β-strand	493	1	42
α-helix	503-505	3
α-helix	511-516	6
α-helix	521-539	19
β-strand	544	1	43
β-strand	557	1	43
α-helix	570-579	10
β-strand	596	1	44
β-strand	599-601	3	45
β-strand	604-605	2	46
β-strand	609-610	2	46
β-strand	612-615	4	45
β-strand	618	1	44
β-strand	620-622	3	47
β-strand	627-628	2	48
β-strand	631	1	49
β-strand	634	1	49
β-strand	638	1	48
β-strand	640-643	4	45
β-strand	644-645	2	50
β-strand	659-660	2	50
β-strand	663-665	3	47
β-strand	669-674	6	45
β-strand	687-688	2	48
α-helix	698-707	10
β-strand	721-724	4	51
α-helix	727-740	14
β-strand	746-749	4	51
β-strand	752	1	52
α-helix	755-758	4
β-strand	773-776	4	51
β-strand	780	1	52
α-helix	785-788	4
β-strand	795-798	4	51
α-helix	806-816	11
β-strand	831-840	10	53
β-strand	845	1	54
β-strand	846-854	9	53
β-strand	862-864	3	53
β-strand	878	1	53
β-strand	886	1	53
β-strand	887	1	55
β-strand	890	1	55
α-helix	903	1
β-strand	904-905	2	53
α-helix	906	1
β-strand	908	1	54
α-helix	914-917	4
β-strand	918	1	56
β-strand	922	1	56
α-helix	927	1
β-strand	928-930	3	53
α-helix	950	1

Chain a: 3 helices, 4 β-strands

Element	Residues	Length	Sheet
β-strand	20-22	3	173
β-strand	29-31	3	173
β-strand	39-43	5	174
α-helix	51-56	6
β-strand	66-70	5	174
α-helix	91-93	3
α-helix	97	1

Chain A: 7 helices, 7 β-strands

Element	Residues	Length	Sheet
α-helix	13-19	7
β-strand	40-41	2	171
β-strand	45-46	2	171
α-helix	50-65	16
β-strand	74-77	4	172
α-helix	83-92	10
β-strand	97-99	3	172
β-strand	121-123	3	172
α-helix	130-136	7
α-helix	137-139	3
β-strand	143-145	3	172
β-strand	159	1	172
α-helix	168-183	16
α-helix	199-201	3

Chain AA: 11 helices, 17 β-strands

Element	Residues	Length	Sheet
α-helix	3-5	3
α-helix	8-10	3
α-helix	29-31	3
α-helix	35-38	4
β-strand	40-50	11	28
α-helix	51	1
β-strand	57-64	8	28
β-strand	71-77	7	28
α-helix	78	1
β-strand	79	1	29
β-strand	83	1	30
β-strand	86-91	6	28
β-strand	101-103	3	28
α-helix	104-106	3
β-strand	112-114	3	28
β-strand	116	1	31
β-strand	126	1	31
β-strand	134-138	5	28
β-strand	145-149	5	28
β-strand	155-159	5	28
β-strand	163-166	4	28
α-helix	168	1
β-strand	169	1	29
α-helix	182-190	9
α-helix	198-200	3
α-helix	201-203	3
β-strand	224-225	2	32
β-strand	237-238	2	32

Chain AB: 10 helices, 20 β-strands

Element	Residues	Length	Sheet
α-helix	9-10	2
β-strand	43	1	57
β-strand	45-58	14	58
β-strand	63	1	59
β-strand	65	1	59
β-strand	72-80	9	58
α-helix	82-83	2
β-strand	84-95	12	60
β-strand	98-106	9	60
α-helix	112-115	4
α-helix	134-137	4
α-helix	142-153	12
β-strand	157-163	7	60
β-strand	179-182	4	60
β-strand	183	1	57
α-helix	189-197	9
β-strand	202-203	2	60
α-helix	205-208	4
β-strand	214-220	7	58
β-strand	225	1	61
α-helix	235-239	5
β-strand	270	1	61
β-strand	274-286	13	58
β-strand	311	1	62
β-strand	315	1	62
β-strand	321-325	5	58
β-strand	335-340	6	58
α-helix	353-354	2
β-strand	356-359	4	58
α-helix	373-379	7

Chain AC: 20 helices, 12 β-strands

Element	Residues	Length	Sheet
β-strand	6-10	5	66
β-strand	13-20	8	66
α-helix	25-27	3
α-helix	32-43	12
β-strand	62-63	2	67
β-strand	76-77	2	67
β-strand	88	1	67
α-helix	98-99	2
α-helix	115-127	13
α-helix	132-137	6
β-strand	151-152	2	66
α-helix	156-158	3
α-helix	162-172	11
α-helix	176-183	8
β-strand	187	1	68
α-helix	192-194	3
β-strand	199	1	68
β-strand	206-209	4	69
α-helix	215-219	5
β-strand	226-229	4	69
α-helix	235-238	4
α-helix	240-242	3
β-strand	248-249	2	69
β-strand	250-251	2	66
α-helix	252-256	5
α-helix	258-261	4
α-helix	276-279	4
α-helix	287-291	5
α-helix	307-309	3
α-helix	322-326	5
α-helix	331-337	7
α-helix	356-361	6

Chain AD: 18 helices, 8 β-strands

Element	Residues	Length	Sheet
α-helix	10-14	5
α-helix	17-19	3
α-helix	22-25	4
α-helix	30-37	8
α-helix	38-40	3
β-strand	50-56	7	72
β-strand	59-66	8	72
β-strand	73-79	7	72
α-helix	80-86	7
α-helix	95-113	19
α-helix	133-135	3
α-helix	139-141	3
β-strand	143	1	73
β-strand	145-146	2	72
α-helix	159-169	11
β-strand	172	1	73
β-strand	183-184	2	74
β-strand	189-190	2	74
α-helix	192-199	8
α-helix	202-213	12
α-helix	216-221	6
α-helix	224-228	5
α-helix	235-247	13
α-helix	262-269	8
α-helix	276-278	3
α-helix	279-293	15

Chain AE: 7 helices, 7 β-strands

Element	Residues	Length	Sheet
α-helix	24-26	3
β-strand	36-40	5	78
β-strand	48-51	4	78
β-strand	52-55	4	79
β-strand	61-63	3	79
α-helix	67-70	4
β-strand	75-77	3	79
α-helix	79-81	3
β-strand	82-88	7	78
α-helix	102-104	3
α-helix	131-148	18
α-helix	154-159	6
β-strand	161	1	78
α-helix	162	1

70 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
25S ribosomal RNA	5	RNA	3364	Kluyveromyces lactis
RNA (121-mer)	7	RNA	121	Kluyveromyces lactis
5.8S ribosomal RNA	8	RNA	2825	Kluyveromyces lactis
KLLA0D16027p	AA	protein	254	Kluyveromyces lactis	Q6CQM3 (AlphaFold model)
60S ribosomal protein L3	AB	protein	387	Kluyveromyces lactis	Q6CJR7 (AlphaFold model)
KLLA0B07139p	AC	protein	363	Kluyveromyces lactis	Q6CW41 (AlphaFold model)
KLLA0D06941p	AD	protein	297	Kluyveromyces lactis	Q6CRR9 (AlphaFold model)
KLLA0B04686p	AE	protein	175	Kluyveromyces lactis	Q6CWE7
KLLA0D03410p	AF	protein	241	Kluyveromyces lactis	Q6CS71
KLLA0E00573p	AG	protein	255	Kluyveromyces lactis	B4UN96
KLLA0F04499p	AH	protein	191	Kluyveromyces lactis	Q6CLA6
KLLA0D05643p	AI	protein	220	Kluyveromyces lactis	Q6CRX7

71 more molecules are not listed.

Sequence of entity 1 (5), FASTA

>6UZ7_1 25S ribosomal RNA (chains 5)
GUUUGACCUCAAAUCAGGUAGGAAUACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGA
AAAGAAACCAACCGGGAUUGCCUUAGUAACGGCGAGUGAAGCGGCAAAAGCUCAAAUUUG
AAAUCUGGCGUCUUCGACGUCCGAGUUGUAAUUUGAAGAAGGCAACUUUGUAGCUGGUCC
UUGUCUAUGUUCCUUGGAACAGGACGUCAUAGAGGGUGAGAAUCCCGUGUGGCGAGGAUC
CCAGUUAUUUGUAAAGUGCUUUCGACGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAGUGG
GUGGUAAAUUCCAUCUAAAGCUAAAUAUUGGCGAGAGACCGAUAGCGAACAAGUACAGUG
AUGGAAAGAUGAAAAGAACUUUGAAAAGAGAGUGAAAAAGUACGUGAAAUUGUUGAAAGG
GAAGGGCAUUUGAUCAGACAUGGCGUUUGCUUCGGCUUUCGCUGGGCCAGCAUCAGUUUU
AGCGGUUGGAUAAAUCCUCGGGAAUGUGGCUCUGCUUCGGUAGAGUGUUAUAGCCCGUGG
GAAUACAGCCAGCUGGGACUGAGGAUUGCGACUUUUGUCAAGGAUGCUGGCGUAAUGGUU
AAAUGCCGCCCGUCUUGAAACACGGACCAAGGAGUCUAACGUCUAUGCGAGUGUUUGGGU
GUAAAACCCGUACGCGUAAUGAAAGUGAACGUAGGUGAGGGCCCGCAAGGGUGCAUCAUC
GACCGAUCCUGAUGUCUUCGGAUGGAUUUGAGUAAGAGCAUAGCUGUUGGGACCCGAAAG
AUGGUGAACUAUGCCUGAAUAGGGUGAAGCCAGAGGAAACUCUGGUGGAGGCUCGUAGCG
GUUCUGACGUGCAAAUCGAUCGUCGAAUUUGGGUAUAGGGGCGAAAGACUAAUCGAACCA
UCUAGUAGCUGGUUCCUGCCGAAGUUUCCCUCAGGAUAGCAGAAGCUCGUAUCAGUUUUA
UGAGGUAAAGCGAAUGAUUAGAGGUACCGGGGUUGAAAUGACCUUGACCUAUUCUCAAAC
UUUAAAUAUGUAAGAAGUCCUUGUUGCUUAAUUGAACGUGGACAUUUGAAUGAAGAGCUU
UUAGUGGGCCAUUUUUGGUAAGCAGAACUGGCGAUGCGGGAUGAACCGAACGUGGAGUUA
AGGUGCCGGAAUACACGCUCAUCAGACACCACAAAAGGUGUUAGUUCAUCUAGACAGCCG
GACGGUGGCCAUGGAAGUCGGAAUCCGCUAAGGAGUGUGUAACAACUCACCGGCCGAAUG
AACUAGCCCUGAAAAUGGAUGGCGCUCAAGCGUGUUACCUAUACUCCACCGUCAGGGUUA
AUAUGAUGCCCUGACGAGUAGGCAGGCGUGGAGGUCAGUGACGAAGCCUAGGCUGUAAAG
CUGGGUAGAACGGCCUCUAGUGCAGAUCUUGGUGGUAGUAGCAAAUAUUCAAAUGAGAAC
UUUGAAGACUGAAGUGGGGAAAGGUUCCACGUCAACAGCAGUUGGACGUGGGUUAGUCGA
UCCUAAGAGAUGGGGAAGCUCCGUUUCAAAGGCCUAAUUUUCUAGGCCACCAUCGAAAGG
GAAUCCGGUUAAUAUUCCGGAACCUGGAUAUGGAUUCUUCACGGUAACGUAACUGAAUGU
GGAGACGUCGGCGCGAGCCCUGGGAGGAGUUAUCUUUUCUUCUUAACAGCUUAUCACCCC
GGAAUUGGUUUAUCCGGAGAGGGGGUCUUAUGGCUGGAAGAGCCCAGCCCUUGUGCUGGG
UCCGGUGCGCCCGCGACGGCCCUUGAAAAUCCACAGGAAGGAAUAGUUUUCAUGCCAGGU
CGUACUGAUAACCGCAGCAGGUCUCCAAGGUGAACAGCCUCUAGUUGAUAGAAUAAUGUA
GAUAAGGGAAGUCGGCAAAAUAGAUCCGUAACUUCGGGAUAAGGAUUGGCUCUAAGGAUC
GGGAAGUGAGGGCCUUGGUCAGACGCGGCGGGCAUGCUUGUGGACUGUCUUACUGGGCUU
GCUCGGUGGGACGGACUGCUUGCGGGCCUUGUUGUAGACGGCCUUGGUAGGUCUCUUGUA
GAUCGUCGCUUGCUGCAAUUAACGAUCAACUUAGAACUGGUACGGACAAGGGGAAUCUGA
CUGUCUAAUUAAAACAUAGCAUUGCGAUGGUCAGAAAGUGAUGUUGACGCAAUGUGAUUU
CUGCCCAGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAACCAAGCGCGGGUAAACGGCGGG
AGUAACUAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUG
AAUGGAUUAACGAGAUUCCCACUGUCCCUAUCUACUAUCUAGCGAAACCACAGCCAAGGG
AACGGGCUUGGCAGAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUUUGAC
AUUGUGAAGAGACAUAGAGGGUGUAGCAUAAGUGGGAGCUUCGGCGCCAGUGAAAUACCA
CUACCUUUAUAGUUUCUUUACUUAUUCAAUUAAGCGGAGCUGGAAUUCAUUUUCCACGUU
CUAGCAUUCAAAGUCCUAUACGGGCUGAUCCGGGUUGAAGACAUUGUCAGGUGGGGAGUU
UGGCUGGGGCGGCACAUCUGUUAAACGAUAACGCAGAUGUCCUAAGGGGGACUCAUGGAG
AACAGAAAUCUCCAGUAGAACAAAAGGGUAAAAGUCCCCUUGAUUUUGAUUUUCAGUGUG
AAUACAAACCAUGAAAGUGUGGCCUAUCGAUCCUUUAGGUCCUCGGAAUUUGAGGCUAGA
GGUGCCAGAAAAGUUACCACAGGGAUAACUGGCUUGUGGCAGUCAAGCGUUCAUAGCGAC
AUUGCUUUUUGAUUCUUCGAUGUCGGCUCUUCCUAUCAUACCGAAGCAGAAUUCGGUAAG
CGUUGGAUUGUUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAG
GUUAGUUUUACCCUACUGAUGAAUGUUAUCGCAAUAGUAAUUGAACUUAGUACGAGAGGA
ACAGUUCAUUCGGAUAAUUGGUUUUUGCGGCUGUCUGAUCAGGCAUUGCCGCGAAGCUAC
CAUCCGCUGGAUUAUGGCUGAACGCCUCUAAGUCAGAAUCCAUGCUAGAACGCGAUGAUU
UCUUUGCCUUGCACAAUAUAGAAGGAUAAGAAUAAGGCGUCUUUUUGGCGUCGCUGAACC
AUAGCAGGCUGGCAACGGUGCUCUUAGCGGAAAGGCUUUGGGUGCUUGCCGGCGAAUUGC
AAUGUCAUUUUGCGCAAGGAUAAAUCAUUUGUAUACGACUUAAAUGUACAACAGGGUAUU
GUAAGCAGUAGAGUAGCCUUGUUGUUACGAUCUGCUGAGAUUAAGCCUUCGUUGUCUGAU
UUGU

Sequence of entity 2 (7), FASTA

>6UZ7_2 RNA (121-MER) (chains 7)
GGUUGCGGCCAUAUCUACCAGAAAGCACCGUUUCCCGUCCGAUCAACUGUAGUUAAGCUG
GUAAGAGCCUGACCGAGUAGUGUAGUGGGUGACCAUACGCGAAACUCAGGUGCUGCAAUC
U

Sequence of entity 3 (8), FASTA

>6UZ7_3 5.8S ribosomal RNA (chains 8)
UCAUUCAAAUUUCUGCCCUAUCAACUUUCGAUGGUAGGAUAGUGGCCUACCAUGGUUUCA
ACGGGUAACGGGGAAUAAGGGUUCGAUUCCGGAGAGGGAGCCUGAGAAACGGCUACCACA
UCCAAGGAAGGCAGCAGGCGCGCAAAUUACCCAAUCCUAAUUCAGGGAGGUAGUGACAAU
AAAUAACGAUACAGGGCCCAUUCGGGUCUUGUAAUUGGAAUGAGUACAAUGUAAAUACCU
UAACGAGGAACAACUGGAGGGCAAGUCUGGUGCCAGCAGCCGCGGUAAUUCCAGCUCCAG
UAGCGUAUAUUAAAGUUGUUGCAGUUAAAAAGCUCGUAGUUGAACUUUGGGUCUGGUUGU
CCGGUCCGACUUUAUGUCGCGCACUGGUUUUCAACCGGAUCUUUCCUUCUGGCUAACCUG
UACUCCUUGUGGGUGCAGGCGAACCAGGACUUUUACUUUGAAAAAAUUAGAGUGUUCAAA
GCAGGCGAAAGCUCGAAUAUAUUAGCAUGGAAUAAUGGAAUAGGACGUUUGGUUCUAUUU
UGUUGGUUUCUAGGACCAUCGUAAUGAUUAAUAGGGACGGUCGGGGGCAUCAGUAUUCAA
UUGUCAGAGGUGAAAUUCUUGGAUUUAUUGAAGACUAACUACUGCGAAAGCAUUUGCCAA
GGACGUUUUCAUUAAUCAAGAACGAAAGUUAGGGGAUCGAAGAUGAUCAGAUACCGUCGU
AGUCUUAACCAUAAACUAUGCCGACUAGGGAUCGGGUGGUGUUUUUCUUAUGACCCACUC
GGCACCUUACGAGAAAUCAAAGUCUUUGGGUUCUGGGGGGAGUAUGGUCGCAAGGCUGAA
ACUUAAAGGAAUUGACGGAAGGGCACCACCAGGAGUGGAGCCUGCGGCUUAAUUUGACUC
AACACGGGGAAACUCACCAGGUCCAGACACAAUAAGGAUUGACAGAUUGAGAGCUCUUUC
UUGAUUUUGUGGGUGGUGGUGCAUGGCCGUUCUUAGUUGGUGGAGUGAUUUGUCUGCUUA
AUUGCGAUAACGAACGAGACCUUAACCUACUAAAUAGGGUUGCUGGCACUUGCCGGUUGA
CUCUUCUUAGAGGGACUAUCGGUUUCAAGCCGAUGGAAGUUUGAGGCAAUAACAGGUCUG
UGAUGCCCUUAGACGUUCUGGGCCGCACGCGCGCUACACUGACGGAGCCAGCGAGUACAA
CCUUGGCCGAGAGGUCUGGGUAAUCUUGUGAAACUCCGUCGUGCUGGGGAUAGAGCAUUG
UAAUUAUUGCUCUUCAACGAGGAAUUCCUAGUAAGCGCAAGUCAUCAGCUUGCGUUGAUU
ACGUCCCUGCCCUUUGUACACACCGCCCGUCGCUAGUACCGAUUGAAUGGCUUAGUGAGG
CCUCAGGAUUUGCUUAGAGAAGGGGGCAACUCCAUCUCAGAGCGAAGAAUCUGGUCAAAC
UUGGUCAUUUAGAGGAACUAAAAGUCGUAACAAGGUUUCCGUAGGUGAACCUGCGGAAGG
AUCAUUAAAGAUUAUGAAUGAGUAGAUUACUGGGGGAAUCGCUGAAUAUGGCCUGCGCUU
AAUUGCGCGGCUAAUUCUUGAUUUUCUGCUAUCAGUUUUCUUUCUCUCAUCCUAAACACA
AUGGAGUUUUUUCUCUAUGAACUACUUCCCUGGAGAGCUCGUCUCUCCAGUGGACAUAAA
CACAAACAACAUUUUGCAUUAUGAAAAACUAUUUAUCAAGAAAUUUAAUAUUCAAAACUU
UCAACAACGGAUCUCUUGGUUCUCGCAUCGAUGAAGAACGCAGCGAAUUGCGAUAUGUAU
UGUGAAUUGCAGAUUUUCGUGAAUCAUCAAAUCUUUGAACGCACAUUGCGCCCUCUGGUA
UUCCAGGGGGCAUGCCUGUUUGAGCGUCAUUUCUCUCUCAAACCUUUGGGUUUGGUAGUG
AGUGAUACUCGUUUUUCGGGUUAACUUGAAAGUGGCUAGCCGUUGCCUUCUGCGUGAGCA
GGGCUGCGUGUCAAGUCUAUGGACUCGACUCUUGCACAUCUACGUCUUAGGUUUGCGCCA
AUUCGUGGUAAGCUAGGGUCAAUGAGCUUAUAGGUGUUAUAAAGACUCGCUGGUGUUUGU
CUCCUUGAGGCAUACGGCUUAAUCAAAACUCUCAAAGUUUGACCUCAAAUCAGGUAGGAA
UACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGAAAAGAAACCAACCGGGAUUGCCUU
AGUAACGGCGAGUGAAGCGGCAAAAGCUCAAAUUUGAAAUCUGGCGUCUUCGACGUCCGA
GUUGUAAUUUGAAGAAGGCAACUUUGUAGCUGGUCCUUGUCUAUGUUCCUUGGAACAGGA
CGUCAUAGAGGGUGAGAAUCCCGUGUGGCGAGGAUCCCAGUUAUUUGUAAAGUGCUUUCG
ACGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAGUGGGUGGUAAAUUCCAUCUAAAGCUAA
AUAUUGGCGAGAGACCGAUAGCGAACAAGUACAGUGAUGGAAAGAUGAAAAGAACUUUGA
AAAGAGAGUGAAAAAGUACGUGAAAUUGUUGAAAGGGAAGGGCAUUUGAUCAGACAUGGC
GUUUGCUUCGGCUUUCGCUGGGCCAGCAUCAGUUUUAGCGGUUGGAUAAAUCCUCGGGAA
UGUGGCUCUGCUUCGGUAGAGUGUUAUAGCCCGUGGGAAUACAGCCAGCUGGGACUGAGG
AUUGCGACUUUUGUCAAGGAUGCUGGCGUAAUGGUUAAAUGCCGCCCGUCUUGAAACACG
GACCAAGGAGUCUAACGUCUAUGCGAGUGUUUGGGUGUAAAACCCGUACGCGUAAUGAAA
GUGAA

Sequence of entity 4 (AA), FASTA

>6UZ7_4 KLLA0D16027p (chains AA)
MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRNLDYAERHGYIRGVVKQIVHDAGRGAPLAK
VVFRDPYKYKLREETFIANEGLHTGQFIYAGKKASLNVGNVLPLGSVPEGTIISNVEERP
GDRGALARASGNYVIVIGHNPEDNKTRVRLPSGAKKIISSDARGVIGVVAGGGRIDKPLL
KAGRAFHKYRVKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAA
RRTGLLRGSQKTQD

Sequence of entity 5 (AB), FASTA

>6UZ7_5 60S ribosomal protein L3 (chains AB)
MSHRKYEAPRHGHLGFLPRKRAASVRGRVKSFPKDDQTKPVALTSFLGYKAGMSTIVRDL
DRPGSKFHKREVVEAVTVVDTPPIVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYK
NWYKSKKKAFTKYSAKYAENGAQVDRELARIKKYASVVRVLVHTQVRKTPLSQKKAHLAE
IQLNGGSVSDKVDWAKEHFEKTVAVDSVFEQNEMIDVVAVTKGHGFEGVTHRWGTKKLPR
KTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHHRTSINHKVYRVGKGDDEANAATEFDR
TKKTITPMGGFVHYGAINNDFVILKGSIPGTRKRVVTLRKSLYTNTSRKALEEVTLKWID
TASKFGKGRFQTPAEKHAFLGTLKKDL

Sequence of entity 6 (AC), FASTA

>6UZ7_6 KLLA0B07139p (chains AC)
MSIPQVAVLSLNGETTSTDLPLPAVFRAPIRPDIVHSVFTSVNKNKRQAYAVSEKAGHQT
SAESWGTGRAVARIPRVGGGGTHRSGQAAFGNMCRGGRMFAPTKTWRKWNVKVNQNEKRY
ATASAIAASAVPSLVLARGHRVEKVPSIPLVVSDDLQSIQKTKEAVAALKAVGAHSDVIK
VVKSKKLRAGKGKYRNRRFTQRRGPLVVYSEDNGVVKAFRNVPGVETANVASLGLLQLAP
GAHLGRFVIWTQSAFSKLDQIWGSETVASVKAGYALPSNIISTSDVTRIINSTEIQSVLR
AAGQATQKRTHVQKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKVDQANKIKPSATALETL
KHD

Sequence of entity 7 (AD), FASTA

>6UZ7_7 KLLA0D06941p (chains AD)
MAFIKDIKTSAYHSRYQTPFRRRREGKTDYYARKRLVAQHKAKYNTPKYRLVVRFTNKDI
ITQIVSSTITGDIVLAAAYSHELPRYGITHGLTNWSAAYATGLLLARRTLQKLGLDETYP
GVEEVEGEYELTEAVEDGPRPFKVYLDVGLQRTTTGARIFGALKGASDGGLYVPHSENRF
PGWDFEAEELDADLLRTYIFGGHVSQYMEELADDDEERYRELFKGYLADDIDADAVEDIY
ADAHAAIREDPAFKPTEKKFTKEQYAAESKKYRQVKLTREERKARVAAKISALAPQE

Sequence of entity 8 (AE), FASTA

>6UZ7_8 KLLA0B04686p (chains AE)
MAQAQKWYPAEEVPAPKQTRKAARPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLEDNT
LLVSGPFKVNGVPLRRVNARYVIATSTRVSLEGVNTEKFNVAYFSREKLSRKQRAEANFF
NEDQPKKEIKAERIEDQKNIDKALLAEIKKTPLLKQYLAATFSLKNGDRPHLLKF

Sequence of entity 9 (AF), FASTA

>6UZ7_9 KLLA0D03410p (chains AF)
MSASKVLVPESQVKKAKAQQKTAEQVAAERVARKAEKRAAILERNAAYQKEYETAERAVI
DAKREAKANSSYYVSAEAKLVFVVRIKGINKIPPKPRKVLQLLRLNQINSGTFVKVTKAT
SELLKLIEPYVAYGYPSYSTVRQLVYKRGYGKINKQRIPLSDNSIVEANLGNYGILSVDD
LIHEIVTVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKSM
N

Sequence of entity 10 (AG), FASTA

>6UZ7_10 KLLA0E00573p (chains AG)
MAPSKKVAPAPLASKAASAKKSNPLTKSSPRNFGIGQAIQPKRNLSRYVKWPEYVRLQRQ
KKILSIRLKVPPSIAQFQNTLDRNTAAETFKLLKKYSPETAAEKKERLTKEAAAIAEGKT
KQEASPKPYVVKYGLNHVVSLIENKKAKLVLIANDVDPIELVIFLPALCKKMGVPYAIVK
GKARLGTLVNQKTSAVAALTEVREEDEAALAKLVSTINANYLEKYEDSKKHWGGGIMGQK
AQKKIEKRAKAAESA

Sequence of entity 11 (AH), FASTA

>6UZ7_11 KLLA0F04499p (chains AH)
MKYIQTDQVLDVPEGVTVQIRSRIIKVTGPRGVLTKNLKHIDVTFTKVSNRQIKITVHNG
DRKHVAALRTVKSLISNLITGVTKGYKYKLRYVYAHFPINVNVIEKDGAKFIEIRNFLGD
KKVREVPVREGVSVDFSTNQKDEIVLSGNSVENVSQNAADIQQICRVRNKDIRKFLDGIY
VSEKGLIEEEE

Sequence of entity 12 (AI), FASTA

>6UZ7_12 KLLA0D05643p (chains AI)
MARRPARCYRYQKNKPYPKSRYNRAVPDSKIRIYDLGKKKATVDEFPLCVHLVSNELEQL
SSEALEAARITANKYITKMTGRDSFHLRVRVHPFHVLRINKMLSCAGADRLQQGMRGAWG
KPHGLAARVAIGQVIFSVRTKDNNKDTVIEGLRRARYKFPGQQKIIISKKWGFTSLNREE
YVKKRDAGEIKDDGAFVKFLSKKGSLEENIREFPEYFAKA

Ligands and cofactors

ID	Name	Formula	Copies
GCP	Phosphomethylphosphonic acid guanylate ester	C11 H18 N5 O13 P3	1
ZN	Zinc ion	Zn	6

Primary citation

Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation. Huang, B.Y., Fernandez, I.S. Proc Natl Acad Sci U S A (2020) 117:1429-1437. DOI 10.1073/pnas.1916436117 · PubMed

Other PDB entries of the same protein (UniProt Q6CQM3 (AlphaFold model), which also has an AlphaFold model), best resolution first:

5IT7 3.6 Å, Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis…

Browse structure collections

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