7KTS: PDB entry 7KTS

Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module). Determined by electron microscopy at 19.09 Å resolution. Released 10 Nov 2021.

Method
Electron microscopy
Resolution
19.09 Å
Organisms
Homo sapiens, unclassified Rhodococcus
Chains
13
Atoms
51,173
Mol. weight
1100.24 kDa
Released
10 Nov 2021

Explore 7KTS in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7KTS contains 335 α-helices and 206 β-strands across 13 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 204 helices, 28 β-strands

ElementResiduesLengthSheet
α-helix347-3493
α-helix352-3543
α-helix360-37415
α-helix381-39515
α-helix402-42322
α-helix425-4273
α-helix431-44717
α-helix448-4525
α-helix453-4586
α-helix460-4612
α-helix524-55330
α-helix567-5704
α-helix571-58717
α-helix588-5925
β-strand593-59531
β-strand601-60331
α-helix604-6052
α-helix612-6143
α-helix615-62713
α-helix632-64211
α-helix645-6528
α-helix654-6563
α-helix657-6659
α-helix670-68314
α-helix692-71120
α-helix713-7208
α-helix721-7233
α-helix724-73512
α-helix742-75615
α-helix762-7676
α-helix768-7703
α-helix771-78313
α-helix788-79912
α-helix809-8157
α-helix816-8238
α-helix827-84317
α-helix846-8538
α-helix854-8563
α-helix857-86711
α-helix873-88614
α-helix887-8915
α-helix892-8943
β-strand911-91662
β-strand921-92662
α-helix928-93912
α-helix945-96117
β-strand96313
α-helix969-9768
α-helix980-9834
α-helix985-9873
α-helix993-9953
α-helix998-10003
α-helix1001-101717
α-helix1023-104523
α-helix1052-10543
α-helix1062-10643
α-helix1079-108911
α-helix1095-111420
α-helix1117-11204
α-helix1124-113411
α-helix1135-11384
α-helix1142-115817
α-helix1161-118121
α-helix1190-120617
α-helix1208-12092
α-helix1216-123621
α-helix1242-125918
α-helix1263-12675
α-helix1268-12736
α-helix1285-12873
α-helix1290-130314
α-helix1318-133215
α-helix1335-13395
α-helix1351-136313
α-helix1368-13703
α-helix1371-138212
α-helix1387-140115
α-helix1408-141912
α-helix1430-144213
α-helix1449-147224
α-helix1479-149315
α-helix1502-151615
α-helix1525-15328
α-helix1536-15438
α-helix1546-15494
α-helix1552-156211
α-helix1568-15758
α-helix1579-15824
α-helix1608-162316
α-helix1627-16293
α-helix1631-164212
α-helix1644-16518
α-helix1662-167615
α-helix1981-19855
α-helix1999-20035
α-helix2010-202415
α-helix2036-204510
α-helix2050-206011
α-helix2063-207614
α-helix2081-20866
α-helix2091-210212
α-helix2105-212016
α-helix2124-213310
α-helix2137-214812
α-helix2156-21594
α-helix2165-21717
α-helix2183-21908
α-helix2197-22037
α-helix2204-22063
α-helix2211-222212
α-helix2228-224417
α-helix2249-22579
α-helix2263-22653
α-helix2272-228312
α-helix2291-230212
α-helix2311-23166
α-helix2317-23226
α-helix2323-23286
α-helix2332-234615
α-helix2353-23553
α-helix2360-237718
α-helix2382-239716
α-helix2406-24105
α-helix2411-24199
α-helix2423-243513
α-helix2441-24466
α-helix2447-24515
α-helix2454-24574
α-helix2463-24719
β-strand247914
β-strand248913
α-helix2490-24912
α-helix2494-24985
α-helix2501-25099
α-helix2557-257317
β-strand257714
α-helix2578-258912
α-helix2593-261018
α-helix2613-262715
α-helix2630-26378
α-helix2642-26509
α-helix2661-267010
α-helix2674-268512
α-helix2699-27013
α-helix2713-272614
α-helix2729-273911
α-helix2743-275210
α-helix2757-277721
α-helix2779-27813
α-helix2782-27843
α-helix2785-280117
α-helix2805-28128
β-strand281315
β-strand281815
α-helix2820-28278
α-helix2828-28303
α-helix2833-284311
α-helix2849-28513
α-helix2852-286514
α-helix2875-289016
α-helix2899-29013
α-helix2902-292322
α-helix2926-29283
α-helix2932-294716
α-helix2956-298025
α-helix2988-301124
α-helix3014-30229
α-helix3023-30264
α-helix3032-304918
α-helix3055-306612
α-helix3075-309117
α-helix3095-310814
α-helix3113-313018
α-helix3133-314614
α-helix3156-316510
α-helix3166-31683
α-helix3174-31829
α-helix3188-31947
α-helix3195-32028
α-helix3207-322014
α-helix3222-324322
α-helix3270-32723
α-helix3273-328816
α-helix3290-330213
α-helix3303-33064
α-helix3310-333223
α-helix33391
β-strand334016
α-helix3341-33422
α-helix3343-335412
α-helix3374-338512
α-helix3389-340113
β-strand341116
α-helix3412-343019
β-strand3436-343837
α-helix3439-34413
α-helix3444-34485
β-strand345718
α-helix34581
β-strand347318
β-strand3474-347747
β-strand3480-348567
β-strand3490-349897
β-strand3503-350977
α-helix3514-353017
α-helix3531-35355
α-helix3540-35434
β-strand3552-355657
β-strand3559-356357
β-strand3568-357039
α-helix3571-358212
α-helix3588-360316
α-helix3609-362214
α-helix3628-36369
α-helix3640-366324
β-strand3666110
α-helix3671-36733
β-strand3674-367749
β-strand3683-368539
β-strand3690110
β-strand3692111
β-strand3699111
α-helix3711-37177
α-helix3719-37235
α-helix3725-373713
α-helix3744-376724
α-helix3776-37783
α-helix3782-380423
α-helix3807-38093
α-helix3812-38209
α-helix3823-38264
α-helix3831-38333
Chain B: 13 helices, 35 β-strands
ElementResiduesLengthSheet
β-strand3112
α-helix4-52
α-helix6-1914
α-helix39-5012
α-helix69-8315
α-helix87-915
α-helix96-10914
α-helix113-12311
α-helix134-1418
α-helix146-1516
α-helix154-1607
α-helix1621
β-strand163-168613
α-helix169-18113
α-helix185-1939
β-strand195-200613
β-strand258-264714
β-strand271-276615
β-strand282-287615
β-strand292-296515
β-strand302116
β-strand320-321217
β-strand333116
β-strand335-338415
β-strand345-350618
β-strand356-361618
β-strand366-370518
β-strand375-380618
β-strand387119
β-strand391-392220
β-strand398-402520
β-strand403119
β-strand408-412520
β-strand415-422820
β-strand429-434621
β-strand440-445621
β-strand450-454521
β-strand460-464521
β-strand471-476622
β-strand482-487622
β-strand492-496522
β-strand501-506622
β-strand513-518623
β-strand524-529623
β-strand533-538623
β-strand555-559523
β-strand566-569414
β-strand576-582714
Chain C: 20 helices, 19 β-strands
ElementResiduesLengthSheet
α-helix2-2120
α-helix23-253
α-helix36-4914
β-strand57113
α-helix63-697
β-strand76-81624
β-strand86-90524
β-strand100124
β-strand104124
α-helix110-1178
β-strand119125
α-helix122-1309
β-strand136-137224
β-strand140-147824
β-strand162-166524
β-strand167125
α-helix170-18011
β-strand186112
α-helix189-20214
α-helix204-2074
α-helix214-22613
α-helix232-24110
α-helix243-2519
α-helix252-2543
α-helix262-27110
α-helix300-3034
α-helix308-3103
α-helix314-3163
β-strand318126
β-strand327126
β-strand333-340827
β-strand350-356727
β-strand363-365327
α-helix3681
β-strand369127
α-helix370-3712
β-strand394-396327
α-helix399-41719
β-strand422-427627
Chain D: 12 helices, 1 β-strand
ElementResiduesLengthSheet
α-helix39-413
α-helix55-573
α-helix58-8629
α-helix113-1164
α-helix137-1404
α-helix145-1484
α-helix151-16919
β-strand173-175328
α-helix176-20732
α-helix215-2228
α-helix230-2356
α-helix236-2405
α-helix241-26121
Chain E: 7 helices, 2 β-strands
ElementResiduesLengthSheet
α-helix14-2613
β-strand31129
α-helix35-6026
α-helix68-7912
α-helix89-10012
α-helix103-1075
α-helix113-1175
α-helix118-1203
β-strand130-131217
Chain F: 21 helices, 6 β-strands
ElementResiduesLengthSheet
β-strand9-10230
α-helix14-2411
α-helix30-5627
β-strand63129
α-helix65-7410
α-helix78-803
β-strand91-93331
β-strand100-102331
β-strand106-108328
α-helix109-1135
α-helix118-1203
α-helix122-1254
β-strand127-133714
α-helix155-16915
α-helix173-18412
α-helix195-2006
α-helix201-2055
α-helix210-22415
α-helix232-2376
α-helix239-2479
α-helix255-2573
α-helix258-27821
α-helix284-2885
α-helix289-29810
α-helix304-31613
α-helix319-33719
α-helix349-37325
Chain G: 7 helices, 2 β-strands
ElementResiduesLengthSheet
α-helix63-708
β-strand76132
α-helix78-10528
β-strand111133
α-helix113-1197
α-helix120-1245
α-helix137-1393
α-helix143-1453
α-helix146-16015
Chain H: 4 helices, 2 β-strands
ElementResiduesLengthSheet
α-helix119-1235
α-helix132-14110
α-helix149-17729
β-strand194-195228
α-helix197-2059
β-strand217131

5 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Transformation/transcription domain-associated protein,Transformation/transcription…Aprotein3848Homo sapiensF2Z2U4
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5LBprotein589Homo sapiensO75529 (AlphaFold model)
Isoform 3 of Transcription factor SPT20 homologCprotein811Homo sapiensQ8NEM7 (AlphaFold model)
STAGA complex 65 subunit gamma, DhaA,STAGA complex 65 subunit gamma,STAGA complex 65 subunit…Dprotein749Homo sapiens, unclassified RhodococcusO94864 (AlphaFold model)
Transcription initiation factor TFIID subunit 9BEprotein251Homo sapiensQ9HBM6
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit…Fprotein622Homo sapiensQ9Y6J9
Transcription initiation factor TFIID subunit 12Gprotein161Homo sapiensQ16514
Transcription initiation factor TFIID subunit 10Hprotein218Homo sapiensQ12962
Transcription initiation protein SPT3 homolog,Transcription initiation protein SPT3…Iprotein317Homo sapiensO75486
Transcriptional adapter 1Jprotein335Homo sapiensQ96BN2
Ataxin-7Nprotein892Homo sapiensO15265
Splicing factor 3B subunit 3Sprotein1217Homo sapiensQ15393

1 more molecules are not listed.

Sequence of entity 1 (A), FASTA
>7KTS_1 Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein,Transformation/transcription domain-associated protein (chains A)
MAFVATQGATVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYST
FLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRPHTKNVLSVMFRF
LETENEENVLICLRIIIELHKQFRPPITQEIHHFLDFVKQIYKELPKVVNRYFENPQVIP
ENTVPPPEMVGMITTIAVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYK
LNIHNVVAEFVPLIMNTIAIQVSAQARQHKLYNKELYADFIAAQIKTLSFLAYIIRIYQE
LVTKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTXXXXXXXXXXXXXXXXXXXX
XXXXXXXXETLRPLAYSTLADLVHHVRQHLPLSDLSLAVQLFAKNIDDESLPSSIQTMSC
KLLLNLVDCIRSKSEQESGNGRDVLMRMLEVFVLKFHTIARYQLSAIFKKCKPQSELGAV
EAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPFEKQGEKDKEDKQT
FQVTDCRSLVKTLVCGVKTITWGITSCKAPGAQFIPNKQLQPKETQIYIKLVKYAMQALD
IYQVQIAGNGQTYIRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVER
ISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMGSNVELSNLYLKLFKLVFGSV
SLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFLP
LLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQTL
VSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNPADSISHVAYRVLGKFGGS
NRKMLKESQKLHYVVTEVQGPSITVEFSDCKASLQLPMEKAIETALDCLKSANTEPYYRR
QAWEVIKCFLVAMMSLEDNKHALYQLLAHPNFTEKTIPNVIISHRYKAQDTPARKTFEQA
LTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLPCYQVGSQPSTAMFHSEE
NGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSYI
VERLCACCYEQAWYAKLGGVVSIKFLMERLPLTWVLQNQQTFLKALLFVMMDLTGEVSNG
AVAMAKTTLEQLLMRCATPLKDEERAEEIVAAQEKSFHHVTHDLVREVTSPNSTVRKQAM
HSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQPR
LFTMDLNVVEHKVFYTELLNLCEAEDSALTKLPCYKSLPSLVPLRIAALNALAACNYLPQ
SREKIIAALFKALNSTNSELQEAGEACMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSLT
LNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNEMKICSAIIN
LFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEATL
NDPQWSRMFMSFLKHKDARPLRDVLAANPNRFITLLLPGGAQTAVRPGSPSTSTMRLDLQ
FQAIKIISIIVKNDDSWLASQHSLVSQLRRVWVSENFQERHRKENMAATNWKEPKLLAYC
LLNYCKRNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXAGTSELVMLSLELVKTRLAVMSMEMRKNFIQAILTSLIEKS
PDAKILRAVVKIVEEWVKNNSPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFL
DLVNYVYRDETLSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVT
CSQNWEAMGNHFWIKQCIELLLAVCEKSTPIGTSCQGAMLPSITNVINLADSHDRAAFAM
VTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKF
LDTLREVKTGALLSAFVQLCHISTTLAEKTWVQLFPRLWKILSDRQQHALAGEISPFLCS
GSHQVQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTHNLWFRSTLMLEHQAFEKG
LSLQIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKYSETATAI
AYEQHGFFEQAQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIRCSKELNQWEALT
EYGQSKGHINPYLVLECAWRVSNWTAMKEALVQVEVSCPKEMAWKVNMYRGYLAICHPEE
QQLSFIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNL
GRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQAIVTAYENSSQHDPSSNN
AMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQL
AGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMH
DVLVKAWAMWGDYLENIFVKERQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFD
DDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPI
RTLYLTLKIEQRERYKSDSGQQQPSSVGNQSHSASDPGPIRATAPMWRCSRIMHMQRELH
PTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFV
KKLVSTFGVGLENVSNVSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGS
MKLHNLISKLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFLMPKPTH
YYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRL
LNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNP
ISRYYDRLATVQARGTQASHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKM
FTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRL
TPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQEDTSS
PLSAAGQPENMDSQQLVSLVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAANSLDNLCRM
DPAWHPWL
Sequence of entity 2 (B), FASTA
>7KTS_2 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (chains B)
MKRVRTEQIQMAVSCYLKRRQYVDSDGPLKQGLRLSQTAEEMAANLTVQSESGCANIVSA
APCQAEPQQYEVQFGRLRNFLTDSDSQHSHEVMPLLYPLFVYLHLNLVQNSPKSTVESFY
SRFHGMFLQNASQKDVIEQLQTTQTIQDILSNFKLRAFLDNKYVVRLQEDSYNYLIRYLQ
SDNNTALCKVLTLHIHLDVQPAKRTDYQLYASGSSSRSENNGLEPPDMPSPILQNEAALE
VLQESIKRVKDGPPSLTTICFYAFYNTEQLLNTAEISPDSKLLAAGFDNSCIKLWSLRSK
KLKSEPHQVDVSRIHLACDILEEEDDEDDNAGTEMKILRGHCGPVYSTRFLADSSGLLSC
SEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLR
IYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNG
KYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIR
NTYCSAPADGSSSELVGVYTGQMSNVLSVQFMACNLLLVTGITQENQEH
Sequence of entity 3 (C), FASTA
>7KTS_3 Isoform 3 of Transcription factor SPT20 homolog (chains C)
MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPEVKKLRRN
VNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEEL
PPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHSI
TSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFKR
YSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAGQHYDLKISKAGNCVDMWKRSPCNL
AIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVKDDYVFECEAGTQYQKTKLTILQSLGD
PLYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKCP
VKMSHSSSGSASLSQVSPGKETDQTETVSVQSSVLGKGVKHRPPPIKLPSSSGNSSSGNY
FTPQQTSSFLKSPTPPPSSKPSSIPRKSSVDLNQVSMLSPAALSPASSSQRSGTPKPSTP
TPTPSSTPHPPDAQSSTPSTPSATPTPQDSGFTPQPTLLTQFAQQQRSLSQAMPVTTIPL
STMVTSITPGTTATQVMANSAGLNFINVVGSVCGAQALMSGSNPMLGCNTGAITPAGINL
SGLLPSGGLLPNALPSAMQAASQAGVPFGLKNTSSLRPLNLLQLPGGSLIFNTLQQQQQQ
LSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQEQALSAQQAAVINLTGVGSFMQSQAAAV
AILAASNGYGSSSSTNSSATSSSAYRQPVKK
Sequence of entity 4 (D), FASTA
>7KTS_4 STAGA complex 65 subunit gamma, DhaA,STAGA complex 65 subunit gamma,STAGA complex 65 subunit gamma, DhaA,STAGA complex 65 subunit gamma,STAGA complex 65 subunit gamma, DhaA (chains D)
MNLQRYWGEIPISSSQTNRSSFDLLPREFRLVXXXXXXXXXXXXXXXXXXXMLDIPSEPC
SLTIHTIQLIQHNRRLRNLIATAQAQNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDC
KNPNAPFQIRHSDPESDFYRGKGEPVTELSWHSCRQLLYQAVATILAHAGFDCANESVLE
TLTDVAHEYCLKFTKLLRFAVDREARLGQTPFPDVMEQVFHEVGIGSVLSLQKFWQHRIK
DYHSYMLQISKQLSEEYERIVNPEKATEDAKPVKIKEEPVSDITFPVSEELEADLASGDQ
SLPMGVLGAQSERFPSNLEVEASPQASSAEVNASPLWNLAHVKMEPQESEEGNVSGHGVL
GSDVFEEPMSGMSEAGIPQSPDDSDSSYGSHSTDSLMGSSPVFNQRCKKRMRKIGTSGED
LYFQSGGSMAEIGTGFPFDPHYVEVLGERMHYVDVGPRDGTPVLFLHGNPTSSYVWRNII
PHVAPTHRCIAPDLIGMGKSDKPDLGYFFDDHVRFMDAFIEALGLEEVVLVIHDWGSALG
FHWAKRNPERVKGIAFMEFIRPIPTWDEWPEFARETFQAFRTTDVGRKLIIDQNVFIEGT
LPMGVVRPLTEVEMDHYREPFLNPVDREPLWRFPNELPIAGEPANIVALVEEYMDWLHQS
PVPKLLFWGTPGVLIPPAEAARLAKSLPNCKAVDIGPGLNLLQEDNPDLIGSEIARWLST
LEISGDYKDHDGDYKDHDIDYKDDDDKGS
Sequence of entity 5 (E), FASTA
>7KTS_5 Transcription initiation factor TFIID subunit 9B (chains E)
MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSH
AKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRY
CLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSKPTTPTIATPQTVSVPNKVATPMSVTS
QRFTVQIPPSQSTPVKPVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEANPLKR
KHEDDDDNDIM
Sequence of entity 6 (F), FASTA
>7KTS_6 TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L,TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L,TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (chains F)
MSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKR
RKLTVEDFNRALRWSSVEAVCGYGSQEALPMRPAREGELYFPEDREVNLVELALATNIPK
GCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXQAAEPNRGGPGGRGCRRLDDLPWDSLLFQESSSGGGAEPSFGSGLP
LPPGGAGPEDPSLSVTLADIYRELYAFFGDSLATRFGTGQPAPTAPRPPGDKKEPAAAPD
SVRKMPQLTASAIVSPHGDESPRGSGGGGPASASGPAASESRPLPRVHRARGAPRQQGPG
TGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPM
IGRTSRPARRWALSDYSLYLPL
Sequence of entity 7 (G), FASTA
>7KTS_7 Transcription initiation factor TFIID subunit 12 (chains G)
MNQFGPSALINLSNFSSIKPEPASTPPQGSMANSTAVVKIPGTPGAGGRLSPENNQVLTK
KKLQDLVREVDPNEQLDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLEVKDVQLHL
ERQWNMWIPGFGSEEIRPYKKACTTEAHKQRMALIRKTTKK
Sequence of entity 8 (H), FASTA
>7KTS_8 Transcription initiation factor TFIID subunit 10 (chains H)
MSCSGSGADPEAAPASAASAPGPAPPVSAPAALPSSTAAENKASPAGTAGGPGAGAAAGG
TGPLAARAGEPAERRGAAPVSAGGAAPPEGAISNGVYVLPSAANGDVKPVVSSTPLVDFL
MQLEDYTPTIPDAVTGYYLNRAGFEASDPRIIRLISLAAQKFISDIANDALQHCKMKGTA
SGSSRSKSKDRKYTLTMEDLTPALSEYGINVKKPHYFT
Sequence of entity 9 (I), FASTA
>7KTS_9 Transcription initiation protein SPT3 homolog,Transcription initiation protein SPT3 homolog,Transcription initiation protein SPT3 homolog (chains I)
MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVVHTQLI
NLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGIDEDDLL
EDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQXXXXXXX
XXXXXCESRQLSFSKKASKFRDWLDCSSMEIKPNVVAMEILAYLAYETVAQLVDLALLVR
QDMVTKAGDPFSHAISATFIQYHNSAESTAACGVEAHSDAIQPCHIREAIRRYSHRIGPL
SPFTNAYRRNGMAFLAC
Sequence of entity 10 (J), FASTA
>7KTS_10 Transcriptional adapter 1 (chains J)
MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHN
DFLLAILTRCQILVSTPDGAGSLPWPGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLS
GAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVE
NHLKDILTSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNNLIESPPAFTAPCA
GQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALN
IERIITKLWHPNHEELQQDKVHRQRLAAKEGLLLC
Sequence of entity 11 (N), FASTA
>7KTS_11 Ataxin-7 (chains N)
MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP
EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG
KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV
PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP
IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL
PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR
SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR
TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP
LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW
NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS
TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS
SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS
SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP
TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS
PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQPKARP
Sequence of entity 12 (S), FASTA
>7KTS_12 Splicing factor 3B subunit 3 (chains S)
MFLYNLTLQRATGISFAIHGNFSGTKQQEIVVSRGKILELLRPDPNTGKVHTLLTVEVFG
VIRSLMAFRLTGGTKDYIVVGSDSGRIVILEYQPSKNMFEKIHQETFGKSGCRRIVPGQF
LAVDPKGRAVMISAIEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENP
MFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEPLEEHGNFLITVPG
GSDGPSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFF
FLAQTEQGDIFKITLETDEDMVTEIRLKYFDTVPVAAAMCVLKTGFLFVASEFGNHYLYQ
IAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDELDSLSPILFCQIADLANEDT
PQLYVACGRGPRSSLRVLRHGLEVSEMAVSELPGNPNAVWTVRRHIEDEFDAYIIVSFVN
ATLVLSIGETVEEVTDSGFLGTTPTLSCSLLGDDALVQVYPDGIRHIRADKRVNEWKTPG
KKTIVKCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQ
RSRFLAVGLVDNTVRIISLDPSDCLQPLSMQALPAQPESLCIVEMGGTEKQDELGERGSI
GFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSW
LSYSYQSRFHLTPLSYETLEFASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFP
LQYTPRKFVIHPESNNLIIIETDHNAYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAA
AFLNENLPESIFGAPKAGNGQWASVIRVMNPIQGNTLDLVQLEQNEAAFSVAVCRFSNTG
EDWYVLVGVAKDLILNPRSVAGGFVYTYKLVNNGEKLEFLHKTPVEEVPAAIAPFQGRVL
IGVGKLLRVYDLGKKKLLRKCENKHIANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQ
LIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTGNKALWDRG
LLNGASQKAEVIMNYHVGETVLSLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHDF
FQHVEMHLRSEHPPLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDRT
PPEVSKKLEDIRTRYAF

Primary citation

Structure of the human SAGA coactivator complex. Herbst, D.A., Esbin, M.N., Louder, R.K. et al. Nat Struct Mol Biol (2021) 28:989-996. DOI 10.1038/s41594-021-00682-7 · PubMed

Browse structure collections

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