7NAC: PDB entry 7NAC
State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model. Determined by electron microscopy at 3.04 Å resolution. Released 9 Nov 2022.
- Method
- Electron microscopy
- Resolution
- 3.04 Å
- Organism
- Saccharomyces cerevisiae BY4741
- Chains
- 58
- Atoms
- 158,246
- Mol. weight
- 2953.33 kDa
- Ligands
- ZN, SAH
- Released
- 9 Nov 2022
Explore 7NAC in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7NAC contains 579 α-helices and 501 β-strands across 55 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 5: 4 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 26-29 | 4 | 17 |
| α-helix | 33-41 | 9 | |
| α-helix | 45-92 | 48 | |
| β-strand | 145-148 | 4 | 49 |
| β-strand | 154-159 | 6 | 49 |
| α-helix | 164-179 | 16 | |
| α-helix | 218-230 | 13 | |
Chain 7: 8 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 14-15 | 2 | 7 |
| β-strand | 20-21 | 2 | 8 |
| α-helix | 24-28 | 5 | |
| β-strand | 30 | 1 | 9 |
| α-helix | 37-39 | 3 | |
| α-helix | 44-46 | 3 | |
| α-helix | 47-59 | 13 | |
| α-helix | 61-62 | 2 | |
| β-strand | 89-90 | 2 | 10 |
| α-helix | 91 | 1 | |
| β-strand | 99 | 1 | 11 |
| α-helix | 105-115 | 11 | |
| α-helix | 126-146 | 21 | |
Chain 8: 25 helices, 1 β-strand
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-14 | 9 | |
| α-helix | 16-32 | 17 | |
| α-helix | 42-49 | 8 | |
| α-helix | 52-61 | 10 | |
| α-helix | 71-74 | 4 | |
| α-helix | 79-82 | 4 | |
| α-helix | 268-284 | 17 | |
| α-helix | 292-304 | 13 | |
| α-helix | 313-328 | 16 | |
| α-helix | 336-348 | 13 | |
| α-helix | 355-366 | 12 | |
| α-helix | 377-390 | 14 | |
| α-helix | 397-419 | 23 | |
| α-helix | 432-435 | 4 | |
| α-helix | 439-454 | 16 | |
| α-helix | 469-471 | 3 | |
| α-helix | 472-483 | 12 | |
| α-helix | 489-491 | 3 | |
| α-helix | 492-509 | 18 | |
| β-strand | 512 | 1 | 89 |
| α-helix | 516-524 | 9 | |
| α-helix | 557-576 | 20 | |
| α-helix | 584-601 | 18 | |
| α-helix | 605-628 | 24 | |
| α-helix | 641-644 | 4 | |
| α-helix | 655-677 | 23 | |
Chain a: 10 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-22 | 17 | |
| β-strand | 31-38 | 8 | 36 |
| β-strand | 51-53 | 3 | 37 |
| β-strand | 68 | 1 | 38 |
| α-helix | 71-80 | 10 | |
| α-helix | 87-89 | 3 | |
| α-helix | 97-106 | 10 | |
| β-strand | 112 | 1 | 38 |
| α-helix | 117-119 | 3 | |
| α-helix | 120-123 | 4 | |
| α-helix | 127-131 | 5 | |
| α-helix | 144-152 | 9 | |
| β-strand | 155-157 | 3 | 37 |
| β-strand | 165-171 | 7 | 36 |
| α-helix | 177-193 | 17 | |
| β-strand | 201-208 | 8 | 36 |
| α-helix | 212-213 | 2 | |
| β-strand | 214-215 | 2 | 36 |
Chain A: 9 helices, 15 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 33-37 | 5 | 20 |
| α-helix | 43-55 | 13 | |
| β-strand | 59-61 | 3 | 20 |
| α-helix | 73-80 | 8 | |
| β-strand | 85-92 | 8 | 20 |
| β-strand | 96-102 | 7 | 20 |
| β-strand | 109-118 | 10 | 20 |
| β-strand | 130 | 1 | 21 |
| β-strand | 133 | 1 | 22 |
| α-helix | 134-135 | 2 | |
| β-strand | 136-139 | 4 | 20 |
| α-helix | 142-144 | 3 | |
| α-helix | 147-160 | 14 | |
| α-helix | 162-163 | 2 | |
| β-strand | 170 | 1 | 22 |
| β-strand | 175-181 | 7 | 20 |
| β-strand | 186-195 | 10 | 20 |
| β-strand | 196-197 | 2 | 10 |
| α-helix | 203-205 | 3 | |
| β-strand | 210-214 | 5 | 20 |
| β-strand | 218-229 | 12 | 20 |
| β-strand | 232-238 | 7 | 20 |
| α-helix | 245-276 | 32 | |
| α-helix | 280-282 | 3 | |
Chain b: 27 helices, 13 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 8-10 | 3 | |
| α-helix | 14-27 | 14 | |
| α-helix | 39-67 | 29 | |
| α-helix | 76-85 | 10 | |
| α-helix | 88-115 | 28 | |
| α-helix | 116-118 | 3 | |
| α-helix | 122-141 | 20 | |
| α-helix | 144-157 | 14 | |
| β-strand | 169 | 1 | 131 |
| β-strand | 172 | 1 | 131 |
| α-helix | 180-187 | 8 | |
| β-strand | 205-210 | 6 | 131 |
| β-strand | 215-220 | 6 | 131 |
| α-helix | 228 | 1 | |
| α-helix | 234-245 | 12 | |
| β-strand | 248 | 1 | 131 |
| β-strand | 251-254 | 4 | 132 |
| α-helix | 259-261 | 3 | |
| α-helix | 264-274 | 11 | |
| α-helix | 275-278 | 4 | |
| β-strand | 283-287 | 5 | 132 |
| α-helix | 304-309 | 6 | |
| β-strand | 315-319 | 5 | 132 |
| α-helix | 327-339 | 13 | |
| β-strand | 364 | 1 | 79 |
| α-helix | 380-383 | 4 | |
| α-helix | 385-388 | 4 | |
| α-helix | 399-405 | 7 | |
| α-helix | 416-418 | 3 | |
| α-helix | 426-428 | 3 | |
| α-helix | 430-433 | 4 | |
| β-strand | 435-436 | 2 | 43 |
| β-strand | 439-440 | 2 | 43 |
| α-helix | 441-444 | 4 | |
| α-helix | 449-465 | 17 | |
| α-helix | 483-510 | 28 | |
| β-strand | 518 | 1 | 133 |
| α-helix | 521-523 | 3 | |
| β-strand | 526-527 | 2 | 134 |
| α-helix | 528-538 | 11 | |
Chain B: 13 helices, 20 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 27-29 | 3 | |
| α-helix | 33-35 | 3 | |
| β-strand | 42-43 | 2 | 39 |
| β-strand | 45-59 | 15 | 40 |
| β-strand | 71-80 | 10 | 40 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-93 | 10 | 41 |
| β-strand | 100-106 | 7 | 41 |
| α-helix | 112-115 | 4 | |
| α-helix | 116-118 | 3 | |
| α-helix | 131-134 | 4 | |
| α-helix | 135-137 | 3 | |
| α-helix | 142-154 | 13 | |
| β-strand | 157-163 | 7 | 41 |
| α-helix | 166-168 | 3 | |
| β-strand | 178-182 | 5 | 41 |
| β-strand | 183-184 | 2 | 39 |
| α-helix | 188-197 | 10 | |
| β-strand | 199 | 1 | 41 |
| β-strand | 202-203 | 2 | 41 |
| β-strand | 214-220 | 7 | 40 |
| α-helix | 221-222 | 2 | |
| β-strand | 223 | 1 | 42 |
| β-strand | 271 | 1 | 42 |
| β-strand | 274-285 | 12 | 40 |
| β-strand | 299 | 1 | 43 |
| β-strand | 311 | 1 | 44 |
| β-strand | 314 | 1 | 44 |
| β-strand | 321-325 | 5 | 40 |
| β-strand | 335-339 | 5 | 40 |
| α-helix | 348-351 | 4 | |
| β-strand | 355-359 | 5 | 40 |
| α-helix | 373-380 | 8 | |
Chain c: 5 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 10-20 | 11 | |
| β-strand | 22-25 | 4 | 125 |
| α-helix | 27-36 | 10 | |
| β-strand | 41-44 | 4 | 125 |
| α-helix | 50-63 | 14 | |
| β-strand | 66-69 | 4 | 125 |
| α-helix | 74-81 | 8 | |
| β-strand | 89-94 | 6 | 125 |
| α-helix | 100-103 | 4 | |
47 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 25S rRNA | 1 | RNA | 3396 | Saccharomyces cerevisiae BY4741 | |
| 5.8S rRNA | 2 | RNA | 158 | Saccharomyces cerevisiae BY4741 | |
| 60S ribosomal subunit assembly/export protein LOC1 | 7 | protein | 204 | Saccharomyces cerevisiae BY4741 | P43586 (AlphaFold model) |
| Ribosome biogenesis protein BRX1 | A | protein | 291 | Saccharomyces cerevisiae BY4741 | Q08235 (AlphaFold model) |
| 60S ribosomal protein L3 | B | protein | 387 | Saccharomyces cerevisiae BY4741 | P14126 (AlphaFold model) |
| 60S ribosomal protein L4-A | C | protein | 362 | Saccharomyces cerevisiae BY4741 | P10664 (AlphaFold model) |
| 60S ribosomal protein L6-A | E | protein | 176 | Saccharomyces cerevisiae BY4741 | Q02326 |
| 60S ribosomal protein L7-A | F | protein | 244 | Saccharomyces cerevisiae BY4741 | P05737 |
| 60S ribosomal protein L9-A | H | protein | 191 | Saccharomyces cerevisiae BY4741 | P05738 |
| rRNA-processing protein EBP2 | J | protein | 427 | Saccharomyces cerevisiae BY4741 | P36049 |
| 60S ribosomal protein L13-A | L | protein | 199 | Saccharomyces cerevisiae BY4741 | Q12690 |
| 60S ribosomal protein L14-A | M | protein | 138 | Saccharomyces cerevisiae BY4741 | P36105 |
46 more molecules are not listed.
Sequence of entity 1 (1), FASTA
>7NAC_1 25S rRNA (chains 1)
GUUUGACCUCAAAUCAGGUAGGAGUACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGA
AAAGAAACCAACCGGGAUUGCCUUAGUAACGGCGAGUGAAGCGGCAAAAGCUCAAAUUUG
AAAUCUGGUACCUUCGGUGCCCGAGUUGUAAUUUGGAGAGGGCAACUUUGGGGCCGUUCC
UUGUCUAUGUUCCUUGGAACAGGACGUCAUAGAGGGUGAGAAUCCCGUGUGGCGAGGAGU
GCGGUUCUUUGUAAAGUGCCUUCGAAGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAGUGG
GUGGUAAAUUCCAUCUAAAGCUAAAUAUUGGCGAGAGACCGAUAGCGAACAAGUACAGUG
AUGGAAAGAUGAAAAGAACUUUGAAAAGAGAGUGAAAAAGUACGUGAAAUUGUUGAAAGG
GAAGGGCAUUUGAUCAGACAUGGUGUUUUGUGCCCUCUGCUCCUUGUGGGUAGGGGAAUC
UCGCAUUUCACUGGGCCAGCAUCAGUUUUGGUGGCAGGAUAAAUCCAUAGGAAUGUAGCU
UGCCUCGGUAAGUAUUAUAGCCUGUGGGAAUACUGCCAGCUGGGACUGAGGACUGCGACG
UAAGUCAAGGAUGCUGGCAUAAUGGUUAUAUGCCGCCCGUCUUGAAACACGGACCAAGGA
GUCUAACGUCUAUGCGAGUGUUUGGGUGUAAAACCCAUACGCGUAAUGAAAGUGAACGUA
GGUUGGGGCCUCGCAAGAGGUGCACAAUCGACCGAUCCUGAUGUCUUCGGAUGGAUUUGA
GUAAGAGCAUAGCUGUUGGGACCCGAAAGAUGGUGAACUAUGCCUGAAUAGGGUGAAGCC
AGAGGAAACUCUGGUGGAGGCUCGUAGCGCGGUUGACGUGCAAAUCGAUCGUCGAAUUUG
GGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCUGCCGAAGUUUCCCU
CAGGAUAGCAGAAGCUCGUAUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGAGGUUCCGGG
GUCGAAAUGACCUUGACCUAUUCUCAAACUUUAAAUAUGUAAGAAGUCCUUGUUACUUAA
UUGAACGUGGACAUUUGAAUGAAGAGCUUUUAGUGGGCCAUUUUUGGUAAGCAGAACUGG
CGAUGCGGGAUGAACCGAACGUAGAGUUAAGGUGCCGGAAUACACGCUCAUCAGACACCA
CAAAAGGUGUUAGUUCAUCUAGACAGCCGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAA
GGAGUGUGUAACAACUCACCGGCCGAAUGAACUAGCCCUGAAAAUGGAUGGCGCUCAAGC
GUGUUACCUAUACUCUACCGUCAGGGUUGAUAUGAUGCCCUGACGAGUAGGCAGGCGUGG
AGGUCAGUGACGAAGCCUAGACCGUAAGGUCGGGUCGAACGGCCUCUAGUGCAGAUCUUG
GUGGUAGUAGCAAAUAUUCAAAUGAGAACUUUGAAGACUGAAGUGGGGAAAGGUUCCACG
UCAACAGCAGUUGGACGUGGGUUAGUCGAUCCUAAGAGAUGGGGAAGCUCCGUUUCAAAG
GCCUGAUUUUAUGCAGGCCACCAUCGAAAGGGAAUCCGGUUAAGAUUCCGGAACCUGGAU
AUGGAUUCUUCACGGUAACGUAACUGAAUGUGGAGACGUCGGCGCGAGCCCUGGGAGGAG
UUAUCUUUUCUUCUUAACAGCUUAUCACCCCGGAAUUGGUUUAUCCGGAGAUGGGGUCUU
AUGGCUGGAAGAGGCCAGCACCUUUGCUGGCUCCGGUGCGCUUGUGACGGCCCGUGAAAA
UCCACAGGAAGGAAUAGUUUUCAUGCCAGGUCGUACUGAUAACCGCAGCAGGUCUCCAAG
GUGAACAGCCUCUAGUUGAUAGAAUAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGU
AACUUCGGGAUAAGGAUUGGCUCUAAGGGUCGGGUAGUGAGGGCCUUGGUCAGACGCAGC
GGGCGUGCUUGUGGACUGCUUGGUGGGGCUUGCUCUGCUAGGCGGACUACUUGCGUGCCU
UGUUGUAGACGGCCUUGGUAGGUCUCUUGUAGACCGUCGCUUGCUACAAUUAACGAUCAA
CUUAGAACUGGUACGGACAAGGGGAAUCUGACUGUCUAAUUAAAACAUAGCAUUGCGAUG
GUCAGAAAGUGAUGUUGACGCAAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAA
GAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAA
AUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUUAACGAGAUUCCCACUGUCCCU
AUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGGCUUGGCAGAAUCAGCGGGGAAAG
AAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUGAAGAGACAUAGAGGGUGUAGAAU
AAGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACCUUUAUAGUUUCUUUACUUAUUCAA
UGAAGCGGAGCUGGAAUUCAUUUUCCACGUUCUAGCAUUCAAGGUCCCAUUCGGGGCUGA
UCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGGCGGCACAUCUGUUAAACGA
UAACGCAGAUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAUCUCCAGUAGAACAAAAGGG
UAAAAGCCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAACCAUGAAAGUGUGGCCUAUC
GAUCCUUUAGUCCCUCGGAAUUUGAGGCUAGAGGUGCCAGAAAAGUUACCACAGGGAUAA
CUGGCUUGUGGCAGUCAAGCGUUCAUAGCGACAUUGCUUUUUGAUUCUUCGAUGUCGGCU
CUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUUGUUCACCCACUAAUAGGGA
ACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAAUGUUA
CCGCAAUAGUAAUUGAACUUAGUACGAGAGGAACAGUUCAUUCGGAUAAUUGGUUUUUGC
GGCUGUCUGAUCAGGCAUUGCCGCGAAGCUACCAUCCGCUGGAUUAUGGCUGAACGCCUC
UAAGUCAGAAUCCAUGCUAGAACGCGGUGAUUUCUUUGCUCCACACAAUAUAGAUGGAUA
CGAAUAAGGCGUCCUUGUGGCGUCGCUGAACCAUAGCAGGCUAGCAACGGUGCACUUGGC
GGAAAGGCCUUGGGUGCUUGCUGGCGAAUUGCAAUGUCAUUUUGCGUGGGGAUAAAUCAU
UUGUAUACGACUUAGAUGUACAACGGGGUAUUGUAAGCAGUAGAGUAGCCUUGUUGUUAC
GAUCUGCUGAGAUUAAGCCUUUGUUGUCUGAUUUGU
Sequence of entity 2 (2), FASTA
>7NAC_2 5.8S rRNA (chains 2)
AAACUUUCAACAACGGAUCUCUUGGUUCUCGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
ACGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCC
UUGGUAUUCCAGGGGGCAUGCCUGUUUGAGCGUCAUUU
Sequence of entity 3 (7), FASTA
>7NAC_3 60S ribosomal subunit assembly/export protein LOC1 (chains 7)
MAPKKPSKRQNLRREVAPEVFQDSQARNQLANVPHLTEKSAQRKPSKTKVKKEQSLARLY
GAKKDKKGKYSEKDLNIPTLNRAIVPGVKIRRGKKGKKFIADNDTLTLNRLITTIGDKYD
DIAESKLEKARRLEEIRELKRKEIERKEALKQDKLEEKKDEIKKKSSVARTIRRKNKRDM
LKSEAKASESKTEGRKVKKVSFAQ
Sequence of entity 4 (A), FASTA
>7NAC_4 Ribosome biogenesis protein BRX1 (chains A)
MSSIYKALAGKSKDNKSEKKQGNVKQFMNKQRTLLISSRGVNYRHRHLIQDLSGLLPHSR
KEPKLDTKKDLQQLNEIAELYNCNNVLFFEARKHQDLYLWLSKPPNGPTIKFYIQNLHTM
DELNFTGNCLKGSRPVLSFDQRFESSPHYQLIKELLVHNFGVPPNARKSKPFIDHVMSFS
IVDDKIWVRTYEISHSTKNKEEYEDGEEDISLVEIGPRFVMTVILILEGSFGGPKIYENK
QYVSPNVVRAQIKQQAAEEAKSRAEAAVERKIKRRENVLAADPLSNDALFK
Sequence of entity 5 (B), FASTA
>7NAC_5 60S ribosomal protein L3 (chains B)
MSHRKYEAPRHGHLGFLPRKRAASIRARVKAFPKDDRSKPVALTSFLGYKAGMTTIVRDL
DRPGSKFHKREVVEAVTVVDTPPVVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYK
NWYKSKKKAFTKYSAKYAQDGAGIERELARIKKYASVVRVLVHTQIRKTPLAQKKAHLAE
IQLNGGSISEKVDWAREHFEKTVAVDSVFEQNEMIDAIAVTKGHGFEGVTHRWGTKKLPR
KTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHSRTSINHKIYRVGKGDDEANGATSFDR
TKKTITPMGGFVHYGEIKNDFIMVKGCIPGNRKRIVTLRKSLYTNTSRKALEEVSLKWID
TASKFGKGRFQTPAEKHAFMGTLKKDL
Sequence of entity 6 (C), FASTA
>7NAC_6 60S ribosomal protein L4-A (chains C)
MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQT
SAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRY
ATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLK
VLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAP
GAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIR
PAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKPAAVFTETLK
HD
Sequence of entity 7 (E), FASTA
>7NAC_7 60S ribosomal protein L6-A (chains E)
MSAQKAPKWYPSEDVAALKKTRKAARPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLED
NTLLISGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYFAKEKLTKKEKKEAN
LFPEQQNKEIKAERVEDQKVVDKALIAEIKKTPLLKQYLSASFSLKNGDKPHMLKF
Sequence of entity 8 (F), FASTA
>7NAC_8 60S ribosomal protein L7-A (chains F)
MAAEKILTPESQLKKSKAQQKTAEQVAAERAARKAANKEKRAIILERNAAYQKEYETAER
NIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVT
KATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILS
IDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLV
KSMN
Sequence of entity 9 (H), FASTA
>7NAC_9 60S ribosomal protein L9-A (chains H)
MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNNQLIKVAVHNG
GRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGD
KKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIY
VSHKGFITEDL
Sequence of entity 10 (J), FASTA
>7NAC_10 rRNA-processing protein EBP2 (chains J)
MAKGFKLKELLSHQKEIEKAEKLENDLKKKKSQELKKEEPTIVTASNLKKLEKKEKKADV
KKEVAADTEEYQSQALSKKEKRKLKKELKKMQEQDATEAQKHMSGDEDESGDDREEEEEE
EEEEEGRLDLEKLAKSDSESEDDSESENDSEEDEDVVAKEESEEKEEQEEEQDVPLSDVE
FDSDADVVPHHKLTVNNTKAMKHALERVQLPWKKHSFQEHQSVTSETNTDEHIKDIYDDT
ERELAFYKQSLDAVLVARDELKRLKVPFKRPLDYFAEMVKSDEHMDKIKGKLIEEASDKK
AREEARRQRQLKKFGKQVQNATLQKRQLEKRETLEKIKSLKNKRKHNEIDHSEFNVGVEE
EVEGKRFDRGRPNGKRAAKNAKYGQGGMKRFKRKNDATSSADVSGFSSRKMKGKTNRPGK
SRRARRF
Sequence of entity 11 (L), FASTA
>7NAC_11 60S ribosomal protein L13-A (chains L)
MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARATRAAKIAPRPLDLLRPVVRA
PTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQNRNQEIFDANVQRLKEYQ
SKIIVFPRNGKAPEAEQVLSAAATFPIAQPATDVEARAVQDNGESAFRTLRLARSEKKFR
GIREKRAREKAEAEAEKKK
Sequence of entity 12 (M), FASTA
>7NAC_12 60S ribosomal protein L14-A (chains M)
MSTDSIVKASNWRLVEVGRVVLIKKGQSAGKLAAIVEIIDQKKVLIDGPKAGVPRQAINL
GQVVLTPLTFALPRGARTATVSKKWAAAAVCEKWAASSWAKKIAQRERRAALTDFERFQV
MVLRKQKRYTVKKALAKA
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| ZN | Zinc ion | Zn | 2 |
| SAH | S-adenosyl-L-homocysteine | C14 H20 N6 O5 S | 1 |
Primary citation
Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Cruz, V.E., Sekulski, K., Peddada, N. et al. Nat Struct Mol Biol (2022) 29:1228-1238. DOI 10.1038/s41594-022-00874-9 · PubMed
Other PDB entries of the same protein (UniProt P43586 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 8V83 2.53 Å, 60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map)
- 8V87 2.66 Å, 60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map)
- 8V84 2.7 Å, 60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map)
- 7R7A 3.04 Å, State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model
- 7R6K 3.17 Å, State E2 nucleolar 60S ribosomal intermediate - Model for Noc2/Noc3 region
- 7R7C 3.71 Å, State E2 nucleolar 60S ribosomal biogenesis intermediate - L1 stalk local model
Browse structure collections
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