7U0H: 60S ribosomal protein L2-A
State NE1 nucleolar 60S ribosome biogenesis intermediate - Overall model. Determined by electron microscopy at 2.76 Å resolution. Released 14 Dec 2022.
- Method
- Electron microscopy
- Resolution
- 2.76 Å
- Organism
- Saccharomyces cerevisiae BY4741
- Chains
- 49
- Atoms
- 124,932
- Mol. weight
- 2357.21 kDa
- Ligands
- MG, ZN
- Released
- 14 Dec 2022
Explore 7U0H in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7U0H contains 390 α-helices and 331 β-strands across 46 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain a: 4 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 72-74 | 3 | 1 |
| α-helix | 75-81 | 7 | |
| α-helix | 84-92 | 9 | |
| β-strand | 99-100 | 2 | 47 |
| β-strand | 101-103 | 3 | 2 |
| α-helix | 104-107 | 4 | |
| β-strand | 111-113 | 3 | 1 |
| β-strand | 124-127 | 4 | 2 |
| β-strand | 129-130 | 2 | 1 |
| α-helix | 132-141 | 10 | |
| β-strand | 144-147 | 4 | 2 |
Chain A: 6 helices, 15 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 30-32 | 3 | |
| α-helix | 34-38 | 5 | |
| β-strand | 40-49 | 10 | 8 |
| β-strand | 58-64 | 7 | 8 |
| β-strand | 71-77 | 7 | 8 |
| α-helix | 78 | 1 | |
| β-strand | 79 | 1 | 9 |
| β-strand | 83 | 1 | 10 |
| β-strand | 87-91 | 5 | 8 |
| β-strand | 101-103 | 3 | 8 |
| α-helix | 104-106 | 3 | |
| β-strand | 112-114 | 3 | 8 |
| β-strand | 116 | 1 | 11 |
| β-strand | 126 | 1 | 11 |
| β-strand | 134-139 | 6 | 8 |
| β-strand | 145-149 | 5 | 8 |
| β-strand | 155-159 | 5 | 8 |
| β-strand | 163-166 | 4 | 8 |
| β-strand | 169 | 1 | 9 |
| α-helix | 174-176 | 3 | |
| α-helix | 182-191 | 10 | |
Chain b: 27 helices, 13 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-12 | 4 | |
| α-helix | 14-28 | 15 | |
| α-helix | 39-67 | 29 | |
| α-helix | 76-85 | 10 | |
| α-helix | 88-116 | 29 | |
| α-helix | 122-142 | 21 | |
| α-helix | 144-159 | 16 | |
| β-strand | 169-173 | 5 | 3 |
| α-helix | 180-187 | 8 | |
| β-strand | 205-211 | 7 | 3 |
| β-strand | 214-220 | 7 | 3 |
| α-helix | 234-245 | 12 | |
| β-strand | 248 | 1 | 3 |
| β-strand | 251-255 | 5 | 3 |
| α-helix | 264-274 | 11 | |
| α-helix | 275-277 | 3 | |
| β-strand | 284-288 | 5 | 3 |
| α-helix | 295-297 | 3 | |
| α-helix | 300-311 | 12 | |
| β-strand | 316-319 | 4 | 3 |
| α-helix | 325-349 | 25 | |
| α-helix | 354-361 | 8 | |
| β-strand | 364 | 1 | 4 |
| α-helix | 375-377 | 3 | |
| α-helix | 380-384 | 5 | |
| α-helix | 385-388 | 4 | |
| α-helix | 396-398 | 3 | |
| α-helix | 399-406 | 8 | |
| α-helix | 426-429 | 4 | |
| β-strand | 435-436 | 2 | 5 |
| β-strand | 439-440 | 2 | 5 |
| α-helix | 441-444 | 4 | |
| α-helix | 449-466 | 18 | |
| β-strand | 478 | 1 | 6 |
| β-strand | 481 | 1 | 6 |
| α-helix | 483-510 | 28 | |
| α-helix | 517-520 | 4 | |
| β-strand | 526 | 1 | 79 |
| α-helix | 528-537 | 10 | |
| α-helix | 543-550 | 8 | |
Chain B: 18 helices, 17 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 14-16 | 3 | |
| α-helix | 32-35 | 4 | |
| α-helix | 40-41 | 2 | |
| β-strand | 42-43 | 2 | 13 |
| β-strand | 45-60 | 16 | 14 |
| β-strand | 70-80 | 11 | 14 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-95 | 12 | 15 |
| β-strand | 98-106 | 9 | 15 |
| α-helix | 112-115 | 4 | |
| α-helix | 116-118 | 3 | |
| α-helix | 122-124 | 3 | |
| α-helix | 134-136 | 3 | |
| α-helix | 142-154 | 13 | |
| β-strand | 157-163 | 7 | 15 |
| α-helix | 166-168 | 3 | |
| α-helix | 176-177 | 2 | |
| β-strand | 178-182 | 5 | 15 |
| β-strand | 183-184 | 2 | 13 |
| α-helix | 188-198 | 11 | |
| β-strand | 202-203 | 2 | 15 |
| α-helix | 205-207 | 3 | |
| β-strand | 214-220 | 7 | 14 |
| α-helix | 221-222 | 2 | |
| β-strand | 223-227 | 5 | 16 |
| β-strand | 268-271 | 4 | 16 |
| β-strand | 274-286 | 13 | 14 |
| β-strand | 299 | 1 | 5 |
| α-helix | 306-307 | 2 | |
| β-strand | 321-325 | 5 | 14 |
| β-strand | 335-340 | 6 | 14 |
| α-helix | 353-354 | 2 | |
| β-strand | 356-359 | 4 | 14 |
| α-helix | 373-380 | 8 | |
| α-helix | 384-386 | 3 | |
Chain c: 4 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 10-20 | 11 | |
| β-strand | 22-25 | 4 | 7 |
| α-helix | 27-36 | 10 | |
| β-strand | 41-44 | 4 | 7 |
| α-helix | 50-63 | 14 | |
| β-strand | 66-69 | 4 | 7 |
| α-helix | 74-81 | 8 | |
| β-strand | 89-94 | 6 | 7 |
Chain C: 27 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 5-9 | 5 | 18 |
| α-helix | 10 | 1 | |
| β-strand | 15-21 | 7 | 18 |
| α-helix | 22-23 | 2 | |
| α-helix | 24-27 | 4 | |
| α-helix | 32-43 | 12 | |
| α-helix | 44-46 | 3 | |
| α-helix | 47-49 | 3 | |
| β-strand | 62-64 | 3 | 19 |
| β-strand | 75-77 | 3 | 19 |
| β-strand | 88 | 1 | 19 |
| α-helix | 98-99 | 2 | |
| α-helix | 115-128 | 14 | |
| α-helix | 132-137 | 6 | |
| β-strand | 150-152 | 3 | 18 |
| α-helix | 154-158 | 5 | |
| α-helix | 162-172 | 11 | |
| α-helix | 175-183 | 9 | |
| β-strand | 186-187 | 2 | 20 |
| α-helix | 188-189 | 2 | |
| α-helix | 191-194 | 4 | |
| β-strand | 199-200 | 2 | 20 |
| β-strand | 206-209 | 4 | 18 |
| α-helix | 215-219 | 5 | |
| β-strand | 226-229 | 4 | 18 |
| α-helix | 235-238 | 4 | |
| α-helix | 240-242 | 3 | |
| β-strand | 248-251 | 4 | 18 |
| α-helix | 252-262 | 11 | |
| α-helix | 276-279 | 4 | |
| α-helix | 286-290 | 5 | |
| α-helix | 293-298 | 6 | |
| α-helix | 300-302 | 3 | |
| α-helix | 321-327 | 7 | |
| α-helix | 330-337 | 8 | |
| α-helix | 339-341 | 3 | |
| α-helix | 344-346 | 3 | |
| α-helix | 353-359 | 7 | |
Chain d: 5 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 8-15 | 8 | 12 |
| α-helix | 16-20 | 5 | |
| α-helix | 25-27 | 3 | |
| α-helix | 28-44 | 17 | |
| β-strand | 49-51 | 3 | 12 |
| α-helix | 53-59 | 7 | |
| β-strand | 70-79 | 10 | 12 |
| β-strand | 89-95 | 7 | 12 |
| α-helix | 104-106 | 3 | |
| β-strand | 107-108 | 2 | 12 |
Chain e: 8 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 7-9 | 3 | |
| α-helix | 18-19 | 2 | |
| α-helix | 41-44 | 4 | |
| α-helix | 55-57 | 3 | |
| α-helix | 58-60 | 3 | |
| β-strand | 72-76 | 5 | 17 |
| α-helix | 79-82 | 4 | |
| α-helix | 83-85 | 3 | |
| β-strand | 92-96 | 5 | 17 |
| α-helix | 102-115 | 14 | |
| β-strand | 119 | 1 | 17 |
38 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 25S rRNA | 1 | RNA | 3396 | Saccharomyces cerevisiae BY4741 | |
| 5.8S rRNA | 2 | RNA | 158 | Saccharomyces cerevisiae BY4741 | |
| ITS2 rRNA | 6 | RNA | 87 | Saccharomyces cerevisiae BY4741 | |
| 60S ribosomal protein L2-A | A | protein | 254 | Saccharomyces cerevisiae BY4741 | P0CX45 (AlphaFold model) |
| 60S ribosomal protein L3 | B | protein | 387 | Saccharomyces cerevisiae BY4741 | P14126 (AlphaFold model) |
| 60S ribosomal protein L4-A | C | protein | 362 | Saccharomyces cerevisiae BY4741 | P10664 (AlphaFold model) |
| 60S ribosomal protein L6-A | E | protein | 176 | Saccharomyces cerevisiae BY4741 | Q02326 (AlphaFold model) |
| 60S ribosomal protein L7-A | F | protein | 244 | Saccharomyces cerevisiae BY4741 | P05737 |
| 60S ribosomal protein L8-A | G | protein | 256 | Saccharomyces cerevisiae BY4741 | P17076 |
| 60S ribosomal protein L9-A | H | protein | 191 | Saccharomyces cerevisiae BY4741 | P05738 |
| Proteasome-interacting protein CIC1 | K | protein | 376 | Saccharomyces cerevisiae BY4741 | P38779 |
| 60S ribosomal protein L13-A | L | protein | 199 | Saccharomyces cerevisiae BY4741 | Q12690 |
37 more molecules are not listed.
Sequence of entity 1 (1), FASTA
>7U0H_1 25S rRNA (chains 1)
GUUUGACCUCAAAUCAGGUAGGAGUACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGA
AAAGAAACCAACCGGGAUUGCCUUAGUAACGGCGAGUGAAGCGGCAAAAGCUCAAAUUUG
AAAUCUGGUACCUUCGGUGCCCGAGUUGUAAUUUGGAGAGGGCAACUUUGGGGCCGUUCC
UUGUCUAUGUUCCUUGGAACAGGACGUCAUAGAGGGUGAGAAUCCCGUGUGGCGAGGAGU
GCGGUUCUUUGUAAAGUGCCUUCGAAGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAGUGG
GUGGUAAAUUCCAUCUAAAGCUAAAUAUUGGCGAGAGACCGAUAGCGAACAAGUACAGUG
AUGGAAAGAUGAAAAGAACUUUGAAAAGAGAGUGAAAAAGUACGUGAAAUUGUUGAAAGG
GAAGGGCAUUUGAUCAGACAUGGUGUUUUGUGCCCUCUGCUCCUUGUGGGUAGGGGAAUC
UCGCAUUUCACUGGGCCAGCAUCAGUUUUGGUGGCAGGAUAAAUCCAUAGGAAUGUAGCU
UGCCUCGGUAAGUAUUAUAGCCUGUGGGAAUACUGCCAGCUGGGACUGAGGACUGCGACG
UAAGUCAAGGAUGCUGGCAUAAUGGUUAUAUGCCGCCCGUCUUGAAACACGGACCAAGGA
GUCUAACGUCUAUGCGAGUGUUUGGGUGUAAAACCCAUACGCGUAAUGAAAGUGAACGUA
GGUUGGGGCCUCGCAAGAGGUGCACAAUCGACCGAUCCUGAUGUCUUCGGAUGGAUUUGA
GUAAGAGCAUAGCUGUUGGGACCCGAAAGAUGGUGAACUAUGCCUGAAUAGGGUGAAGCC
AGAGGAAACUCUGGUGGAGGCUCGUAGCGGUUCUGACGUGCAAAUCGAUCGUCGAAUUUG
GGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCUGCCGAAGUUUCCCU
CAGGAUAGCAGAAGCUCGUAUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGAGGUUCCGGG
GUCGAAAUGACCUUGACCUAUUCUCAAACUUUAAAUAUGUAAGAAGUCCUUGUUACUUAA
UUGAACGUGGACAUUUGAAUGAAGAGCUUUUAGUGGGCCAUUUUUGGUAAGCAGAACUGG
CGAUGCGGGAUGAACCGAACGUAGAGUUAAGGUGCCGGAAUACACGCUCAUCAGACACCA
CAAAAGGUGUUAGUUCAUCUAGACAGCCGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAA
GGAGUGUGUAACAACUCACCGGCCGAAUGAACUAGCCCUGAAAAUGGAUGGCGCUCAAGC
GUGUUACCUAUACUCUACCGUCAGGGUUGAUAUGAUGCCCUGACGAGUAGGCAGGCGUGG
AGGUCAGUGACGAAGCCUAGACCGUAAGGUCGGGUCGAACGGCCUCUAGUGCAGAUCUUG
GUGGUAGUAGCAAAUAUUCAAAUGAGAACUUUGAAGACUGAAGUGGGGAAAGGUUCCACG
UCAACAGCAGUUGGACGUGGGUUAGUCGAUCCUAAGAGAUGGGGAAGCUCCGUUUCAAAG
GCCUGAUUUUAUGCAGGCCACCAUCGAAAGGGAAUCCGGUUAAGAUUCCGGAACCUGGAU
AUGGAUUCUUCACGGUAACGUAACUGAAUGUGGAGACGUCGGCGCGAGCCCUGGGAGGAG
UUAUCUUUUCUUCUUAACAGCUUAUCACCCCGGAAUUGGUUUAUCCGGAGAUGGGGUCUU
AUGGCUGGAAGAGGCCAGCACCUUUGCUGGCUCCGGUGCGCUUGUGACGGCCCGUGAAAA
UCCACAGGAAGGAAUAGUUUUCAUGCCAGGUCGUACUGAUAACCGCAGCAGGUCUCCAAG
GUGAACAGCCUCUAGUUGAUAGAAUAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGU
AACUUCGGGAUAAGGAUUGGCUCUAAGGGUCGGGUAGUGAGGGCCUUGGUCAGACGCAGC
GGGCGUGCUUGUGGACUGCUUGGUGGGGCUUGCUCUGCUAGGCGGACUACUUGCGUGCCU
UGUUGUAGACGGCCUUGGUAGGUCUCUUGUAGACCGUCGCUUGCUACAAUUAACGAUCAA
CUUAGAACUGGUACGGACAAGGGGAAUCUGACUGUCUAAUUAAAACAUAGCAUUGCGAUG
GUCAGAAAGUGAUGUUGACGCAAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAA
GAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAA
AUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUUAACGAGAUUCCCACUGUCCCU
AUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGGCUUGGCAGAAUCAGCGGGGAAAG
AAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUGAAGAGACAUAGAGGGUGUAGAAU
AAGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACCUUUAUAGUUUCUUUACUUAUUCAA
UGAAGCGGAGCUGGAAUUCAUUUUCCACGUUCUAGCAUUCAAGGUCCCAUUCGGGGCUGA
UCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGGCGGCACAUCUGUUAAACGA
UAACGCAGAUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAUCUCCAGUAGAACAAAAGGG
UAAAAGCCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAACCAUGAAAGUGUGGCCUAUC
GAUCCUUUAGUCCCUCGGAAUUUGAGGCUAGAGGUGCCAGAAAAGUUACCACAGGGAUAA
CUGGCUUGUGGCAGUCAAGCGUUCAUAGCGACAUUGCUUUUUGAUUCUUCGAUGUCGGCU
CUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUUGUUCACCCACUAAUAGGGA
ACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAAUGUUA
CCGCAAUAGUAAUUGAACUUAGUACGAGAGGAACAGUUCAUUCGGAUAAUUGGUUUUUGC
GGCUGUCUGAUCAGGCAUUGCCGCGAAGCUACCAUCCGCUGGAUUAUGGCUGAACGCCUC
UAAGUCAGAAUCCAUGCUAGAACGCGGUGAUUUCUUUGCUCCACACAAUAUAGAUGGAUA
CGAAUAAGGCGUCCUUGUGGCGUCGCUGAACCAUAGCAGGCUAGCAACGGUGCACUUGGC
GGAAAGGCCUUGGGUGCUUGCUGGCGAAUUGCAAUGUCAUUUUGCGUGGGGAUAAAUCAU
UUGUAUACGACUUAGAUGUACAACGGGGUAUUGUAAGCAGUAGAGUAGCCUUGUUGUUAC
GAUCUGCUGAGAUUAAGCCUUUGUUGUCUGAUUUGU
Sequence of entity 2 (2), FASTA
>7U0H_2 5.8S rRNA (chains 2)
AAACUUUCAACAACGGAUCUCUUGGUUCUCGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
ACGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCC
UUGGUAUUCCAGGGGGCAUGCCUGUUUGAGCGUCAUUU
Sequence of entity 3 (6), FASTA
>7U0H_3 ITS2 rRNA (chains 6)
CCUUCUCAAACAUUCUGUUUGGUAGUGAGUGAUACUCUUUGGAGUUAACUUGAAAUUGCU
GGCCUUUAGGCGAACAAUGUUCUUAAA
Sequence of entity 4 (A), FASTA
>7U0H_4 60S ribosomal protein L2-A (chains A)
MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAK
VVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKP
GDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLL
KAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAA
RRTGLLRGSQKTQD
Sequence of entity 5 (B), FASTA
>7U0H_5 60S ribosomal protein L3 (chains B)
MSHRKYEAPRHGHLGFLPRKRAASIRARVKAFPKDDRSKPVALTSFLGYKAGMTTIVRDL
DRPGSKFHKREVVEAVTVVDTPPVVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYK
NWYKSKKKAFTKYSAKYAQDGAGIERELARIKKYASVVRVLVHTQIRKTPLAQKKAHLAE
IQLNGGSISEKVDWAREHFEKTVAVDSVFEQNEMIDAIAVTKGHGFEGVTHRWGTKKLPR
KTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHSRTSINHKIYRVGKGDDEANGATSFDR
TKKTITPMGGFVHYGEIKNDFIMVKGCIPGNRKRIVTLRKSLYTNTSRKALEEVSLKWID
TASKFGKGRFQTPAEKHAFMGTLKKDL
Sequence of entity 6 (C), FASTA
>7U0H_6 60S ribosomal protein L4-A (chains C)
MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQT
SAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRY
ATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLK
VLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAP
GAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIR
PAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKPAAVFTETLK
HD
Sequence of entity 7 (E), FASTA
>7U0H_7 60S ribosomal protein L6-A (chains E)
MSAQKAPKWYPSEDVAALKKTRKAARPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLED
NTLLISGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYFAKEKLTKKEKKEAN
LFPEQQNKEIKAERVEDQKVVDKALIAEIKKTPLLKQYLSASFSLKNGDKPHMLKF
Sequence of entity 8 (F), FASTA
>7U0H_8 60S ribosomal protein L7-A (chains F)
MAAEKILTPESQLKKSKAQQKTAEQVAAERAARKAANKEKRAIILERNAAYQKEYETAER
NIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVT
KATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILS
IDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLV
KSMN
Sequence of entity 9 (G), FASTA
>7U0H_9 60S ribosomal protein L8-A (chains G)
MAPGKKVAPAPFGAKSTKSNKTRNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRVQR
QKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAVAEGK
SKQDASPKPYAVKYGLNHVVALIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIV
KGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGN
KAQAKMDKRAKNSDSA
Sequence of entity 10 (H), FASTA
>7U0H_10 60S ribosomal protein L9-A (chains H)
MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNNQLIKVAVHNG
GRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGD
KKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIY
VSHKGFITEDL
Sequence of entity 11 (K), FASTA
>7U0H_11 Proteasome-interacting protein CIC1 (chains K)
MAKKSNSKKSTPVSTPSKEKKKVIEKKSSTAIPRERVIKAVNELIKFTSKPQDENNEEGN
NGKKNLLEDDEEELKKDLQLIVVNNKSFTGTSKSFKLKLLNVKHSFYKPWKEASATAVKD
FKVLLILKDSDIKKVSEDDLFDQLDSEGIKVDEIICGKDLKTVYKAYEARNAFISQFSLI
LADDSIVTSLPKLMGGKAYNKVETTPISIRTHANKEFSLTTLTNNIKKVYMNQLPVKLPR
GTTLNVHLGNLEWLRPEEFVDNVELISEQLIKAYQIRSIFIKTNRSPVLPLYYNQDVLDE
LEAKKDKIEETHEDDMVTIDGVQVHLSTFNKGLMEIANPSELGSIFSKQINNAKKRSSSE
LEKESSESEAVKKAKS
Sequence of entity 12 (L), FASTA
>7U0H_12 60S ribosomal protein L13-A (chains L)
MAISKNLPILKNHFRKHWQERVKVHFDQAGKKVSRRNARATRAAKIAPRPLDLLRPVVRA
PTVKYNRKVRAGRGFTLAEVKAAGLTAAYARTIGIAVDHRRQNRNQEIFDANVQRLKEYQ
SKIIVFPRNGKAPEAEQVLSAAATFPIAQPATDVEARAVQDNGESAFRTLRLARSEKKFR
GIREKRAREKAEAEAEKKK
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| MG | Magnesium ion | Mg | 1 |
| ZN | Zinc ion | Zn | 4 |
Primary citation
Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Cruz, V.E., Sekulski, K., Peddada, N. et al. Nat Struct Mol Biol (2022) 29:1228-1238. DOI 10.1038/s41594-022-00874-9 · PubMed
Other PDB entries of the same protein (UniProt P0CX45 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 9PN5 1.75 Å, Composite map of hypomethylated 80S ribosome treated with hygromycin B
- 8CCS 1.97 Å, 80S S. cerevisiae ribosome with ligands in hybrid-1 pre-translocation (PRE-H1) complex
- 8CDR 2.04 Å, Translocation intermediate 2 (TI-2) of 80S S. cerevisiae ribosome with ligands and eEF2…
- 8CEH 2.05 Å, Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2…
- 8P8N 2.15 Å, Mouse RPL39 integrated into the yeast 60S ribosomal subunit
- 8PFR 2.15 Å, Mouse RPL39L integrated into the yeast 60S ribosomal subunit
- 8EVT 2.2 Å, Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome…
- 8T2Y 2.2 Å, Hypomethylated yeast 80S bound with cycloheximide, P-site tRNA, and A-site tRNA,…
- 8P8U 2.23 Å, Yeast 60S ribosomal subunit
- 8CGN 2.28 Å, Non-rotated 80S S. cerevisiae ribosome with ligands
- 8ZHC 2.3 Å, pre-frameshift complex of yeast 80S ribosome with eRF1 and mRNA of WNV
- 7UOO 2.34 Å, Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state
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