7UG6: Pre-60S ribosomal subunit, unmethylated G2922
Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922. Determined by electron microscopy at 2.9 Å resolution. Released 21 Dec 2022.
- Method
- Electron microscopy
- Resolution
- 2.9 Å
- Organism
- Saccharomyces cerevisiae S288C
- Chains
- 52
- Atoms
- 140,950
- Mol. weight
- 2338.39 kDa
- Ligands
- MG, GDP
- Released
- 21 Dec 2022
Explore 7UG6 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7UG6 contains 429 α-helices and 400 β-strands across 49 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 7: 4 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 11-20 | 10 | |
| β-strand | 24-25 | 2 | 6 |
| α-helix | 27-35 | 9 | |
| β-strand | 41-44 | 4 | 6 |
| α-helix | 50-63 | 14 | |
| β-strand | 66-69 | 4 | 6 |
| α-helix | 74-80 | 7 | |
| β-strand | 89-92 | 4 | 6 |
Chain a: 4 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 72-74 | 3 | 7 |
| α-helix | 78-80 | 3 | |
| α-helix | 84-93 | 10 | |
| β-strand | 99-100 | 2 | 55 |
| β-strand | 101-103 | 3 | 8 |
| α-helix | 104-107 | 4 | |
| β-strand | 111-113 | 3 | 7 |
| β-strand | 124-127 | 4 | 8 |
| β-strand | 129-130 | 2 | 7 |
| α-helix | 132-140 | 9 | |
| β-strand | 144-147 | 4 | 8 |
Chain A: 8 helices, 17 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-9 | 4 | |
| α-helix | 10-12 | 3 | |
| β-strand | 18 | 1 | 9 |
| α-helix | 28-31 | 4 | |
| α-helix | 34-38 | 5 | |
| β-strand | 40-49 | 10 | 10 |
| β-strand | 58-64 | 7 | 10 |
| β-strand | 71-77 | 7 | 10 |
| α-helix | 78 | 1 | |
| β-strand | 79 | 1 | 11 |
| β-strand | 83 | 1 | 12 |
| β-strand | 87-91 | 5 | 10 |
| β-strand | 101-103 | 3 | 10 |
| β-strand | 112-114 | 3 | 10 |
| β-strand | 116 | 1 | 13 |
| β-strand | 126 | 1 | 13 |
| β-strand | 134-140 | 7 | 10 |
| β-strand | 145-149 | 5 | 10 |
| β-strand | 155-159 | 5 | 10 |
| β-strand | 163-166 | 4 | 10 |
| β-strand | 169 | 1 | 11 |
| α-helix | 174-176 | 3 | |
| α-helix | 182-190 | 9 | |
| β-strand | 193 | 1 | 9 |
| α-helix | 201-203 | 3 | |
Chain b: 25 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 8-10 | 3 | |
| α-helix | 14-28 | 15 | |
| α-helix | 39-67 | 29 | |
| α-helix | 76-85 | 10 | |
| α-helix | 88-116 | 29 | |
| α-helix | 122-141 | 20 | |
| α-helix | 144-157 | 14 | |
| β-strand | 169-174 | 6 | 14 |
| β-strand | 178 | 1 | 15 |
| β-strand | 181 | 1 | 15 |
| α-helix | 183-187 | 5 | |
| β-strand | 205-211 | 7 | 14 |
| β-strand | 214-220 | 7 | 14 |
| α-helix | 229-231 | 3 | |
| α-helix | 234-245 | 12 | |
| β-strand | 248-255 | 8 | 14 |
| α-helix | 264-273 | 10 | |
| α-helix | 275-278 | 4 | |
| β-strand | 282-288 | 7 | 14 |
| α-helix | 295-297 | 3 | |
| α-helix | 300-309 | 10 | |
| β-strand | 315-319 | 5 | 14 |
| α-helix | 325-348 | 24 | |
| β-strand | 364 | 1 | 16 |
| α-helix | 380-383 | 4 | |
| α-helix | 385-388 | 4 | |
| α-helix | 399-405 | 7 | |
| α-helix | 417-419 | 3 | |
| α-helix | 425-427 | 3 | |
| α-helix | 430-433 | 4 | |
| β-strand | 435-436 | 2 | 17 |
| β-strand | 439-440 | 2 | 17 |
| α-helix | 441-444 | 4 | |
| α-helix | 449-466 | 18 | |
| α-helix | 597-609 | 13 | |
| α-helix | 611-614 | 4 | |
Chain B: 16 helices, 17 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 20-22 | 3 | |
| α-helix | 33-35 | 3 | |
| α-helix | 40-41 | 2 | |
| β-strand | 42-43 | 2 | 18 |
| β-strand | 45-60 | 16 | 19 |
| β-strand | 70-80 | 11 | 19 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-96 | 13 | 20 |
| β-strand | 98-106 | 9 | 20 |
| α-helix | 112-117 | 6 | |
| α-helix | 131-138 | 8 | |
| α-helix | 142-154 | 13 | |
| β-strand | 157-164 | 8 | 20 |
| α-helix | 166-168 | 3 | |
| β-strand | 178-182 | 5 | 20 |
| β-strand | 183-184 | 2 | 18 |
| α-helix | 188-198 | 11 | |
| β-strand | 202-203 | 2 | 20 |
| α-helix | 205-207 | 3 | |
| β-strand | 214-220 | 7 | 19 |
| β-strand | 223-227 | 5 | 21 |
| α-helix | 229-232 | 4 | |
| α-helix | 235-238 | 4 | |
| β-strand | 268-271 | 4 | 21 |
| β-strand | 274-286 | 13 | 19 |
| β-strand | 299 | 1 | 17 |
| α-helix | 306-307 | 2 | |
| β-strand | 321-325 | 5 | 19 |
| β-strand | 335-340 | 6 | 19 |
| α-helix | 349-351 | 3 | |
| α-helix | 352-354 | 3 | |
| β-strand | 356-359 | 4 | 19 |
| α-helix | 373-380 | 8 | |
Chain c: 4 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-32 | 21 | |
| α-helix | 37-39 | 3 | |
| α-helix | 53-63 | 11 | |
| α-helix | 91-111 | 21 | |
Chain C: 28 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-4 | 2 | |
| β-strand | 5-9 | 5 | 22 |
| β-strand | 15-21 | 7 | 22 |
| α-helix | 22-23 | 2 | |
| α-helix | 24-27 | 4 | |
| α-helix | 32-42 | 11 | |
| β-strand | 62-64 | 3 | 23 |
| β-strand | 75-77 | 3 | 23 |
| β-strand | 88 | 1 | 23 |
| α-helix | 98-99 | 2 | |
| α-helix | 115-127 | 13 | |
| α-helix | 128-130 | 3 | |
| α-helix | 132-137 | 6 | |
| β-strand | 150-152 | 3 | 22 |
| α-helix | 154-158 | 5 | |
| α-helix | 162-172 | 11 | |
| α-helix | 175-183 | 9 | |
| β-strand | 186-187 | 2 | 24 |
| α-helix | 188-189 | 2 | |
| α-helix | 191-194 | 4 | |
| β-strand | 199-200 | 2 | 24 |
| β-strand | 206-209 | 4 | 22 |
| α-helix | 215-219 | 5 | |
| β-strand | 226-229 | 4 | 22 |
| α-helix | 235-238 | 4 | |
| α-helix | 240-242 | 3 | |
| β-strand | 248-251 | 4 | 22 |
| α-helix | 252-262 | 11 | |
| α-helix | 276-279 | 4 | |
| α-helix | 286-290 | 5 | |
| α-helix | 293-298 | 6 | |
| α-helix | 300-301 | 2 | |
| α-helix | 307-310 | 4 | |
| α-helix | 314-316 | 3 | |
| α-helix | 321-327 | 7 | |
| α-helix | 331-337 | 7 | |
| α-helix | 339-341 | 3 | |
| α-helix | 342-346 | 5 | |
| α-helix | 353-360 | 8 | |
Chain d: 5 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 8-11 | 4 | 25 |
| β-strand | 13-15 | 3 | 26 |
| α-helix | 16-19 | 4 | |
| α-helix | 25-27 | 3 | |
| α-helix | 28-44 | 17 | |
| β-strand | 49-51 | 3 | 25 |
| α-helix | 53-59 | 7 | |
| α-helix | 60-62 | 3 | |
| β-strand | 70-72 | 3 | 26 |
| β-strand | 73-79 | 7 | 25 |
| β-strand | 89-95 | 7 | 25 |
| β-strand | 107-108 | 2 | 25 |
41 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 25S rRNA | 1 | RNA | 3396 | Saccharomyces cerevisiae S288C | |
| 5.8S rRNA | 2 | RNA | 158 | Saccharomyces cerevisiae S288C | |
| 5S rRNA | 3 | RNA | 121 | Saccharomyces cerevisiae S288C | |
| 60S ribosomal protein L30 | 7 | protein | 105 | Saccharomyces cerevisiae S288C | P14120 (AlphaFold model) |
| 60S ribosomal protein L2-A | A | protein | 254 | Saccharomyces cerevisiae S288C | P0CX45 (AlphaFold model) |
| 60S ribosomal protein L3 | B | protein | 387 | Saccharomyces cerevisiae S288C | P14126 (AlphaFold model) |
| 60S ribosomal protein L4-A | C | protein | 362 | Saccharomyces cerevisiae S288C | P10664 (AlphaFold model) |
| 60S ribosomal protein L5 | D | protein | 297 | Saccharomyces cerevisiae S288C | P26321 |
| 60S ribosomal protein L6-A | E | protein | 176 | Saccharomyces cerevisiae S288C | Q02326 |
| 60S ribosomal protein L7-A | F | protein | 244 | Saccharomyces cerevisiae S288C | P05737 |
| 60S ribosomal protein L8-A | G | protein | 256 | Saccharomyces cerevisiae S288C | P17076 |
| 60S ribosomal protein L9-A | H | protein | 191 | Saccharomyces cerevisiae S288C | P05738 |
40 more molecules are not listed.
Sequence of entity 1 (1), FASTA
>7UG6_1 25S rRNA (chains 1)
GUUUGACCUCAAAUCAGGUAGGAGUACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGA
AAAGAAACCAACCGGGAUUGCCUUAGUAACGGCGAGUGAAGCGGCAAAAGCUCAAAUUUG
AAAUCUGGUACCUUCGGUGCCCGAGUUGUAAUUUGGAGAGGGCAACUUUGGGGCCGUUCC
UUGUCUAUGUUCCUUGGAACAGGACGUCAUAGAGGGUGAGAAUCCCGUGUGGCGAGGAGU
GCGGUUCUUUGUAAAGUGCCUUCGAAGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAGUGG
GUGGUAAAUUCCAUCUAAAGCUAAAUAUUGGCGAGAGACCGAUAGCGAACAAGUACAGUG
AUGGAAAGAUGAAAAGAACUUUGAAAAGAGAGUGAAAAAGUACGUGAAAUUGUUGAAAGG
GAAGGGCAUUUGAUCAGACAUGGUGUUUUGUGCCCUCUGCUCCUUGUGGGUAGGGGAAUC
UCGCAUUUCACUGGGCCAGCAUCAGUUUUGGUGGCAGGAUAAAUCCAUAGGAAUGUAGCU
UGCCUCGGUAAGUAUUAUAGCCUGUGGGAAUACUGCCAGCUGGGACUGAGGACUGCGACG
UAAGUCAAGGAUGCUGGCAUAAUGGUUAUAUGCCGCCCGUCUUGAAACACGGACCAAGGA
GUCUAACGUCUAUGCGAGUGUUUGGGUGUAAAACCCAUACGCGUAAUGAAAGUGAACGUA
GGUUGGGGCCUCGCAAGAGGUGCACAAUCGACCGAUCCUGAUGUCUUCGGAUGGAUUUGA
GUAAGAGCAUAGCUGUUGGGACCCGAAAGAUGGUGAACUAUGCCUGAAUAGGGUGAAGCC
AGAGGAAACUCUGGUGGAGGCUCGUAGCGGUUCUGACGUGCAAAUCGAUCGUCGAAUUUG
GGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCUGCCGAAGUUUCCCU
CAGGAUAGCAGAAGCUCGUAUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGAGGUUCCGGG
GUCGAAAUGACCUUGACCUAUUCUCAAACUUUAAAUAUGUAAGAAGUCCUUGUUACUUAA
UUGAACGUGGACAUUUGAAUGAAGAGCUUUUAGUGGGCCAUUUUUGGUAAGCAGAACUGG
CGAUGCGGGAUGAACCGAACGUAGAGUUAAGGUGCCGGAAUACACGCUCAUCAGACACCA
CAAAAGGUGUUAGUUCAUCUAGACAGCCGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAA
GGAGUGUGUAACAACUCACCGGCCGAAUGAACUAGCCCUGAAAAUGGAUGGCGCUCAAGC
GUGUUACCUAUACUCUACCGUCAGGGUUGAUAUGAUGCCCUGACGAGUAGGCAGGCGUGG
AGGUCAGUGACGAAGCCUAGACCGUAAGGUCGGGUCGAACGGCCUCUAGUGCAGAUCUUG
GUGGUAGUAGCAAAUAUUCAAAUGAGAACUUUGAAGACUGAAGUGGGGAAAGGUUCCACG
UCAACAGCAGUUGGACGUGGGUUAGUCGAUCCUAAGAGAUGGGGAAGCUCCGUUUCAAAG
GCCUGAUUUUAUGCAGGCCACCAUCGAAAGGGAAUCCGGUUAAGAUUCCGGAACCUGGAU
AUGGAUUCUUCACGGUAACGUAACUGAAUGUGGAGACGUCGGCGCGAGCCCUGGGAGGAG
UUAUCUUUUCUUCUUAACAGCUUAUCACCCCGGAAUUGGUUUAUCCGGAGAUGGGGUCUU
AUGGCUGGAAGAGGCCAGCACCUUUGCUGGCUCCGGUGCGCUUGUGACGGCCCGUGAAAA
UCCACAGGAAGGAAUAGUUUUCAUGCCAGGUCGUACUGAUAACCGCAGCAGGUCUCCAAG
GUGAACAGCCUCUAGUUGAUAGAAUAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGU
AACUUCGGGAUAAGGAUUGGCUCUAAGGGUCGGGUAGUGAGGGCCUUGGUCAGACGCAGC
GGGCGUGCUUGUGGACUGCUUGGUGGGGCUUGCUCUGCUAGGCGGACUACUUGCGUGCCU
UGUUGUAGACGGCCUUGGUAGGUCUCUUGUAGACCGUCGCUUGCUACAAUUAACGAUCAA
CUUAGAACUGGUACGGACAAGGGGAAUCUGACUGUCUAAUUAAAACAUAGCAUUGCGAUG
GUCAGAAAGUGAUGUUGACGCAAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAA
GAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAA
AUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUUAACGAGAUUCCCACUGUCCCU
AUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGGCUUGGCAGAAUCAGCGGGGAAAG
AAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUGAAGAGACAUAGAGGGUGUAGAAU
AAGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACCUUUAUAGUUUCUUUACUUAUUCAA
UGAAGCGGAGCUGGAAUUCAUUUUCCACGUUCUAGCAUUCAAGGUCCCAUUCGGGGCUGA
UCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGGCGGCACAUCUGUUAAACGA
UAACGCAGAUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAUCUCCAGUAGAACAAAAGGG
UAAAAGCCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAACCAUGAAAGUGUGGCCUAUC
GAUCCUUUAGUCCCUCGGAAUUUGAGGCUAGAGGUGCCAGAAAAGUUACCACAGGGAUAA
CUGGCUUGUGGCAGUCAAGCGUUCAUAGCGACAUUGCUUUUUGAUUCUUCGAUGUCGGCU
CUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUUGUUCACCCACUAAUAGGGA
ACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAAUGUUA
CCGCAAUAGUAAUUGAACUUAGUACGAGAGGAACAGUUCAUUCGGAUAAUUGGUUUUUGC
GGCUGUCUGAUCAGGCAUUGCCGCGAAGCUACCAUCCGCUGGAUUAUGGCUGAACGCCUC
UAAGUCAGAAUCCAUGCUAGAACGCGGUGAUUUCUUUGCUCCACACAAUAUAGAUGGAUA
CGAAUAAGGCGUCCUUGUGGCGUCGCUGAACCAUAGCAGGCUAGCAACGGUGCACUUGGC
GGAAAGGCCUUGGGUGCUUGCUGGCGAAUUGCAAUGUCAUUUUGCGUGGGGAUAAAUCAU
UUGUAUACGACUUAGAUGUACAACGGGGUAUUGUAAGCAGUAGAGUAGCCUUGUUGUUAC
GAUCUGCUGAGAUUAAGCCUUUGUUGUCUGAUUUGU
Sequence of entity 2 (2), FASTA
>7UG6_2 5.8S rRNA (chains 2)
AAACUUUCAACAACGGAUCUCUUGGUUCUCGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
ACGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCC
UUGGUAUUCCAGGGGGCAUGCCUGUUUGAGCGUCAUUU
Sequence of entity 3 (3), FASTA
>7UG6_3 5S rRNA (chains 3)
GGUUGCGGCCAUAUCUACCAGAAAGCACCGUUUCCCGUCCGAUCAACUGUAGUUAAGCUG
GUAAGAGCCUGACCGAGUAGUGUAGUGGGUGACCAUACGCGAAACUCAGGUGCUGCAAUC
U
Sequence of entity 4 (7), FASTA
>7UG6_4 60S ribosomal protein L30 (chains 7)
MAPVKSQESINQKLALVIKSGKYTLGYKSTVKSLRQGKSKLIIIAANTPVLRKSELEYYA
MLSKTKVYYFQGGNNELGTAVGKLFRVGVVSILEAGDSDILTTLA
Sequence of entity 5 (A), FASTA
>7UG6_5 60S ribosomal protein L2-A (chains A)
MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAK
VVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKP
GDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLL
KAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAA
RRTGLLRGSQKTQD
Sequence of entity 6 (B), FASTA
>7UG6_6 60S ribosomal protein L3 (chains B)
MSHRKYEAPRHGHLGFLPRKRAASIRARVKAFPKDDRSKPVALTSFLGYKAGMTTIVRDL
DRPGSKFHKREVVEAVTVVDTPPVVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYK
NWYKSKKKAFTKYSAKYAQDGAGIERELARIKKYASVVRVLVHTQIRKTPLAQKKAHLAE
IQLNGGSISEKVDWAREHFEKTVAVDSVFEQNEMIDAIAVTKGHGFEGVTHRWGTKKLPR
KTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHSRTSINHKIYRVGKGDDEANGATSFDR
TKKTITPMGGFVHYGEIKNDFIMVKGCIPGNRKRIVTLRKSLYTNTSRKALEEVSLKWID
TASKFGKGRFQTPAEKHAFMGTLKKDL
Sequence of entity 7 (C), FASTA
>7UG6_7 60S ribosomal protein L4-A (chains C)
MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQT
SAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRY
ATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLK
VLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAP
GAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIR
PAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKPAAVFTETLK
HD
Sequence of entity 8 (D), FASTA
>7UG6_8 60S ribosomal protein L5 (chains D)
MAFQKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTNKDI
ICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGLLIARRTLQKLGLDETYK
GVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRF
PGWDFETEEIDPELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIY
TSAHEAIRADPAFKPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ
Sequence of entity 9 (E), FASTA
>7UG6_9 60S ribosomal protein L6-A (chains E)
MSAQKAPKWYPSEDVAALKKTRKAARPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLED
NTLLISGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYFAKEKLTKKEKKEAN
LFPEQQNKEIKAERVEDQKVVDKALIAEIKKTPLLKQYLSASFSLKNGDKPHMLKF
Sequence of entity 10 (F), FASTA
>7UG6_10 60S ribosomal protein L7-A (chains F)
MAAEKILTPESQLKKSKAQQKTAEQVAAERAARKAANKEKRAIILERNAAYQKEYETAER
NIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVT
KATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILS
IDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLV
KSMN
Sequence of entity 11 (G), FASTA
>7UG6_11 60S ribosomal protein L8-A (chains G)
MAPGKKVAPAPFGAKSTKSNKTRNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRVQR
QKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAVAEGK
SKQDASPKPYAVKYGLNHVVALIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIV
KGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGN
KAQAKMDKRAKNSDSA
Sequence of entity 12 (H), FASTA
>7UG6_12 60S ribosomal protein L9-A (chains H)
MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNNQLIKVAVHNG
GRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGD
KKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIY
VSHKGFITEDL
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| MG | Magnesium ion | Mg | 1 |
| GDP | Guanosine-5'-diphosphate | C10 H15 N5 O11 P2 | 1 |
Primary citation
A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome. Yelland, J.N., Bravo, J.P.K., Black, J.J. et al. Nat Struct Mol Biol (2023) 30:91-98. DOI 10.1038/s41594-022-00891-8 · PubMed
Other PDB entries of the same protein (UniProt P14120 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 9PN5 1.75 Å, Composite map of hypomethylated 80S ribosome treated with hygromycin B
- 8CCS 1.97 Å, 80S S. cerevisiae ribosome with ligands in hybrid-1 pre-translocation (PRE-H1) complex
- 8CDR 2.04 Å, Translocation intermediate 2 (TI-2) of 80S S. cerevisiae ribosome with ligands and eEF2…
- 8CEH 2.05 Å, Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2…
- 8P8N 2.15 Å, Mouse RPL39 integrated into the yeast 60S ribosomal subunit
- 8PFR 2.15 Å, Mouse RPL39L integrated into the yeast 60S ribosomal subunit
- 8EVT 2.2 Å, Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome…
- 8T2Y 2.2 Å, Hypomethylated yeast 80S bound with cycloheximide, P-site tRNA, and A-site tRNA,…
- 8P8U 2.23 Å, Yeast 60S ribosomal subunit
- 8CGN 2.28 Å, Non-rotated 80S S. cerevisiae ribosome with ligands
- 8ZHC 2.3 Å, pre-frameshift complex of yeast 80S ribosome with eRF1 and mRNA of WNV
- 1NMU 2.31 Å, Mbp-L30
Browse structure collections
About this viewer
MolViewer shows 7UG6 directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.