7UQB: 60S ribosomal protein L2-A
Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A strain with AlF4. Determined by electron microscopy at 2.43 Å resolution. Released 15 Mar 2023.
- Method
- Electron microscopy
- Resolution
- 2.43 Å
- Organism
- Saccharomyces cerevisiae BY4741
- Chains
- 60
- Atoms
- 157,949
- Mol. weight
- 2620.53 kDa
- Ligands
- B3P, MG, ZN, GDP
- Released
- 15 Mar 2023
Explore 7UQB in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7UQB contains 557 α-helices and 485 β-strands across 56 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 4: 27 helices, 29 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 22-46 | 25 | |
| α-helix | 47-52 | 6 | |
| α-helix | 61-77 | 17 | |
| β-strand | 87-97 | 11 | 60 |
| β-strand | 100-102 | 3 | 61 |
| α-helix | 108-110 | 3 | |
| α-helix | 111-118 | 8 | |
| α-helix | 126-130 | 5 | |
| β-strand | 138-147 | 10 | 60 |
| β-strand | 150-159 | 10 | 60 |
| α-helix | 162 | 1 | |
| β-strand | 163 | 1 | 62 |
| α-helix | 164 | 1 | |
| β-strand | 172 | 1 | 62 |
| β-strand | 176-177 | 2 | 57 |
| α-helix | 179-199 | 21 | |
| α-helix | 204-206 | 3 | |
| β-strand | 219 | 1 | 63 |
| α-helix | 220-233 | 14 | |
| β-strand | 236-238 | 3 | 60 |
| α-helix | 239 | 1 | |
| β-strand | 243-247 | 5 | 60 |
| β-strand | 248 | 1 | 64 |
| β-strand | 251 | 1 | 64 |
| β-strand | 266-268 | 3 | 60 |
| α-helix | 271-279 | 9 | |
| β-strand | 310 | 1 | 63 |
| β-strand | 316-325 | 10 | 60 |
| β-strand | 333-339 | 7 | 61 |
| α-helix | 344-346 | 3 | |
| β-strand | 359-362 | 4 | 65 |
| α-helix | 373-385 | 13 | |
| β-strand | 390-391 | 2 | 65 |
| α-helix | 392-395 | 4 | |
| α-helix | 399 | 1 | |
| α-helix | 401 | 1 | |
| α-helix | 406-428 | 23 | |
| β-strand | 432-434 | 3 | 65 |
| α-helix | 435-437 | 3 | |
| β-strand | 438-444 | 7 | 61 |
| α-helix | 445-450 | 6 | |
| α-helix | 456-458 | 3 | |
| β-strand | 461 | 1 | 76 |
| β-strand | 466 | 1 | 75 |
| α-helix | 467-470 | 4 | |
| β-strand | 475 | 1 | 66 |
| β-strand | 480 | 1 | 66 |
| α-helix | 482-491 | 10 | |
| β-strand | 496 | 1 | 61 |
| β-strand | 500-510 | 11 | 60 |
| β-strand | 521-524 | 4 | 60 |
| α-helix | 533-535 | 3 | |
| β-strand | 537-539 | 3 | 57 |
| α-helix | 548-561 | 14 | |
| β-strand | 569-571 | 3 | 60 |
| α-helix | 572-576 | 5 | |
Chain 5: 2 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 43-96 | 54 | |
| α-helix | 101-111 | 11 | |
Chain 8: 8 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 10-18 | 9 | 52 |
| α-helix | 29-35 | 7 | |
| α-helix | 39-49 | 11 | |
| β-strand | 57-65 | 9 | 52 |
| β-strand | 70-74 | 5 | 52 |
| α-helix | 77-84 | 8 | |
| α-helix | 87-89 | 3 | |
| β-strand | 103-104 | 2 | 53 |
| α-helix | 106-116 | 11 | |
| α-helix | 125-139 | 15 | |
| β-strand | 142-143 | 2 | 53 |
| β-strand | 146 | 1 | 53 |
| α-helix | 148-157 | 10 | |
| α-helix | 161-162 | 2 | |
Chain 9: 4 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 3 | 1 | 55 |
| β-strand | 6 | 1 | 55 |
| α-helix | 12-33 | 22 | |
| α-helix | 53-63 | 11 | |
| β-strand | 84-85 | 2 | 56 |
| α-helix | 91-110 | 20 | |
| α-helix | 139-151 | 13 | |
| β-strand | 167-169 | 3 | 57 |
Chain a: 4 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 72-74 | 3 | 58 |
| α-helix | 75-81 | 7 | |
| α-helix | 84-92 | 9 | |
| β-strand | 99-100 | 2 | 117 |
| β-strand | 101-103 | 3 | 59 |
| α-helix | 104-107 | 4 | |
| β-strand | 111-113 | 3 | 58 |
| β-strand | 124-127 | 4 | 59 |
| β-strand | 129-130 | 2 | 58 |
| α-helix | 132-141 | 10 | |
| β-strand | 144-147 | 4 | 59 |
Chain A: 11 helices, 15 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-5 | 3 | |
| α-helix | 6-9 | 4 | |
| α-helix | 10-12 | 3 | |
| α-helix | 14-16 | 3 | |
| α-helix | 29-31 | 3 | |
| α-helix | 34-38 | 5 | |
| β-strand | 40-49 | 10 | 1 |
| β-strand | 58-64 | 7 | 1 |
| β-strand | 71-77 | 7 | 1 |
| α-helix | 78 | 1 | |
| β-strand | 79 | 1 | 2 |
| β-strand | 83 | 1 | 3 |
| α-helix | 86 | 1 | |
| β-strand | 87-91 | 5 | 1 |
| β-strand | 101-103 | 3 | 1 |
| α-helix | 104-106 | 3 | |
| β-strand | 112-114 | 3 | 1 |
| β-strand | 116 | 1 | 4 |
| β-strand | 126 | 1 | 4 |
| β-strand | 134-140 | 7 | 1 |
| β-strand | 145-149 | 5 | 1 |
| β-strand | 155-159 | 5 | 1 |
| β-strand | 163-166 | 4 | 1 |
| β-strand | 169 | 1 | 2 |
| α-helix | 174-176 | 3 | |
| α-helix | 182-190 | 9 | |
Chain b: 28 helices, 14 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 14-28 | 15 | |
| α-helix | 39-67 | 29 | |
| α-helix | 76-86 | 11 | |
| α-helix | 88-116 | 29 | |
| α-helix | 122-141 | 20 | |
| α-helix | 144-157 | 14 | |
| β-strand | 168-174 | 7 | 73 |
| α-helix | 180-187 | 8 | |
| β-strand | 205-211 | 7 | 73 |
| β-strand | 214-220 | 7 | 73 |
| α-helix | 234-245 | 12 | |
| β-strand | 249-255 | 7 | 73 |
| α-helix | 264-273 | 10 | |
| β-strand | 282-288 | 7 | 73 |
| α-helix | 300-311 | 12 | |
| β-strand | 317-319 | 3 | 73 |
| α-helix | 325-348 | 24 | |
| α-helix | 355-361 | 7 | |
| β-strand | 364 | 1 | 50 |
| α-helix | 380-384 | 5 | |
| α-helix | 385-388 | 4 | |
| α-helix | 396-398 | 3 | |
| α-helix | 399-406 | 8 | |
| α-helix | 416-419 | 4 | |
| α-helix | 425-427 | 3 | |
| α-helix | 431-433 | 3 | |
| β-strand | 435 | 1 | 71 |
| β-strand | 440 | 1 | 71 |
| α-helix | 449-466 | 18 | |
| β-strand | 478 | 1 | 74 |
| β-strand | 481 | 1 | 74 |
| α-helix | 483-510 | 28 | |
| α-helix | 517-520 | 4 | |
| β-strand | 525-527 | 3 | 10 |
| α-helix | 528-538 | 11 | |
| α-helix | 543-555 | 13 | |
| α-helix | 562-567 | 6 | |
| β-strand | 574 | 1 | 75 |
| α-helix | 575-577 | 3 | |
| β-strand | 595 | 1 | 76 |
| α-helix | 596-609 | 14 | |
| α-helix | 611-615 | 5 | |
Chain B: 21 helices, 19 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-10 | 2 | |
| α-helix | 14-16 | 3 | |
| α-helix | 27-28 | 2 | |
| α-helix | 32-35 | 4 | |
| α-helix | 40-41 | 2 | |
| β-strand | 42-43 | 2 | 67 |
| β-strand | 45-60 | 16 | 68 |
| β-strand | 70-80 | 11 | 68 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-95 | 12 | 69 |
| β-strand | 98-106 | 9 | 69 |
| α-helix | 112-115 | 4 | |
| α-helix | 116-118 | 3 | |
| α-helix | 133-137 | 5 | |
| α-helix | 139-141 | 3 | |
| α-helix | 144-154 | 11 | |
| β-strand | 157-163 | 7 | 69 |
| α-helix | 166-168 | 3 | |
| β-strand | 178-182 | 5 | 69 |
| β-strand | 183-184 | 2 | 67 |
| α-helix | 188-198 | 11 | |
| β-strand | 202-203 | 2 | 69 |
| α-helix | 205-207 | 3 | |
| β-strand | 214-220 | 7 | 68 |
| α-helix | 221-223 | 3 | |
| β-strand | 226-227 | 2 | 70 |
| α-helix | 229-232 | 4 | |
| α-helix | 235-239 | 5 | |
| β-strand | 268-269 | 2 | 70 |
| β-strand | 274-286 | 13 | 68 |
| β-strand | 299 | 1 | 71 |
| α-helix | 307 | 1 | |
| β-strand | 311 | 1 | 72 |
| β-strand | 315 | 1 | 72 |
| β-strand | 321-325 | 5 | 68 |
| β-strand | 335-339 | 5 | 68 |
| α-helix | 348-350 | 3 | |
| β-strand | 356-359 | 4 | 68 |
| α-helix | 373-380 | 8 | |
| α-helix | 384-386 | 3 | |
48 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 60S ribosomal protein L2-A | A | protein | 254 | Saccharomyces cerevisiae BY4741 | P0CX45 (AlphaFold model) |
| 25S rRNA | 1 | RNA | 3396 | Saccharomyces cerevisiae BY4741 | |
| 5.8S rRNA | 2 | RNA | 158 | Saccharomyces cerevisiae BY4741 | |
| 5S rRNA | 3 | RNA | 121 | Saccharomyces cerevisiae BY4741 | |
| rRNA-processing protein | 5 | protein | 120 | Saccharomyces cerevisiae BY4741 | P53188 (AlphaFold model) |
| ITS2 rRNA | 6 | RNA | 74 | Saccharomyces cerevisiae BY4741 | |
| 60S ribosomal protein L12-A | 8 | protein | 165 | Saccharomyces cerevisiae BY4741 | P0CX53 (AlphaFold model) |
| Ribosome biogenesis protein ALB1 | 9 | protein | 175 | Saccharomyces cerevisiae BY4741 | P47019 (AlphaFold model) |
| 60S ribosomal protein L3 | B | protein | 387 | Saccharomyces cerevisiae BY4741 | P14126 |
| 60S ribosomal protein L4-A | C | protein | 362 | Saccharomyces cerevisiae BY4741 | P10664 |
| 60S ribosomal protein L5 | D | protein | 297 | Saccharomyces cerevisiae BY4741 | P26321 |
| 60S ribosomal protein L6-A | E | protein | 176 | Saccharomyces cerevisiae BY4741 | Q02326 |
48 more molecules are not listed.
Sequence of entity 1 (A), FASTA
>7UQB_1 60S ribosomal protein L2-A (chains A)
MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAK
VVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKP
GDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLL
KAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAA
RRTGLLRGSQKTQD
Sequence of entity 2 (1), FASTA
>7UQB_2 25S rRNA (chains 1)
GUUUGACCUCAAAUCAGGUAGGAGUACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGA
AAAGAAACCAACCGGGAUUGCCUUAGUAACGGCGAGUGAAGCGGCAAAAGCUCAAAUUUG
AAAUCUGGUACCUUCGGUGCCCGAGUUGUAAUUUGGAGAGGGCAACUUUGGGGCCGUUCC
UUGUCUAUGUUCCUUGGAACAGGACGUCAUAGAGGGUGAGAAUCCCGUGUGGCGAGGAGU
GCGGUUCUUUGUAAAGUGCCUUCGAAGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAGUGG
GUGGUAAAUUCCAUCUAAAGCUAAAUAUUGGCGAGAGACCGAUAGCGAACAAGUACAGUG
AUGGAAAGAUGAAAAGAACUUUGAAAAGAGAGUGAAAAAGUACGUGAAAUUGUUGAAAGG
GAAGGGCAUUUGAUCAGACAUGGUGUUUUGUGCCCUCUGCUCCUUGUGGGUAGGGGAAUC
UCGCAUUUCACUGGGCCAGCAUCAGUUUUGGUGGCAGGAUAAAUCCAUAGGAAUGUAGCU
UGCCUCGGUAAGUAUUAUAGCCUGUGGGAAUACUGCCAGCUGGGACUGAGGACUGCGACG
UAAGUCAAGGAUGCUGGCAUAAUGGUUAUAUGCCGCCCGUCUUGAAACACGGACCAAGGA
GUCUAACGUCUAUGCGAGUGUUUGGGUGUAAAACCCAUACGCGUAAUGAAAGUGAACGUA
GGUUGGGGCCUCGCAAGAGGUGCACAAUCGACCGAUCCUGAUGUCUUCGGAUGGAUUUGA
GUAAGAGCAUAGCUGUUGGGACCCGAAAGAUGGUGAACUAUGCCUGAAUAGGGUGAAGCC
AGAGGAAACUCUGGUGGAGGCUCGUAGCGGUUCUGACGUGCAAAUCGAUCGUCGAAUUUG
GGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCUGCCGAAGUUUCCCU
CAGGAUAGCAGAAGCUCGUAUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGAGGUUCCGGG
GUCGAAAUGACCUUGACCUAUUCUCAAACUUUAAAUAUGUAAGAAGUCCUUGUUACUUAA
UUGAACGUGGACAUUUGAAUGAAGAGCUUUUAGUGGGCCAUUUUUGGUAAGCAGAACUGG
CGAUGCGGGAUGAACCGAACGUAGAGUUAAGGUGCCGGAAUACACGCUCAUCAGACACCA
CAAAAGGUGUUAGUUCAUCUAGACAGCCGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAA
GGAGUGUGUAACAACUCACCGGCCGAAUGAACUAGCCCUGAAAAUGGAUGGCGCUCAAGC
GUGUUACCUAUACUCUACCGUCAGGGUUGAUAUGAUGCCCUGACGAGUAGGCAGGCGUGG
AGGUCAGUGACGAAGCCUAGACCGUAAGGUCGGGUCGAACGGCCUCUAGUGCAGAUCUUG
GUGGUAGUAGCAAAUAUUCAAAUGAGAACUUUGAAGACUGAAGUGGGGAAAGGUUCCACG
UCAACAGCAGUUGGACGUGGGUUAGUCGAUCCUAAGAGAUGGGGAAGCUCCGUUUCAAAG
GCCUGAUUUUAUGCAGGCCACCAUCGAAAGGGAAUCCGGUUAAGAUUCCGGAACCUGGAU
AUGGAUUCUUCACGGUAACGUAACUGAAUGUGGAGACGUCGGCGCGAGCCCUGGGAGGAG
UUAUCUUUUCUUCUUAACAGCUUAUCACCCCGGAAUUGGUUUAUCCGGAGAUGGGGUCUU
AUGGCUGGAAGAGGCCAGCACCUUUGCUGGCUCCGGUGCGCUUGUGACGGCCCGUGAAAA
UCCACAGGAAGGAAUAGUUUUCAUGCCAGGUCGUACUGAUAACCGCAGCAGGUCUCCAAG
GUGAACAGCCUCUAGUUGAUAGAAUAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGU
AACUUCGGGAUAAGGAUUGGCUCUAAGGGUCGGGUAGUGAGGGCCUUGGUCAGACGCAGC
GGGCGUGCUUGUGGACUGCUUGGUGGGGCUUGCUCUGCUAGGCGGACUACUUGCGUGCCU
UGUUGUAGACGGCCUUGGUAGGUCUCUUGUAGACCGUCGCUUGCUACAAUUAACGAUCAA
CUUAGAACUGGUACGGACAAGGGGAAUCUGACUGUCUAAUUAAAACAUAGCAUUGCGAUG
GUCAGAAAGUGAUGUUGACGCAAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAA
GAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAA
AUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUUAACGAGAUUCCCACUGUCCCU
AUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGGCUUGGCAGAAUCAGCGGGGAAAG
AAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUGAAGAGACAUAGAGGGUGUAGAAU
AAGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACCUUUAUAGUUUCUUUACUUAUUCAA
UGAAGCGGAGCUGGAAUUCAUUUUCCACGUUCUAGCAUUCAAGGUCCCAUUCGGGGCUGA
UCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGGCGGCACAUCUGUUAAACGA
UAACGCAGAUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAUCUCCAGUAGAACAAAAGGG
UAAAAGCCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAACCAUGAAAGUGUGGCCUAUC
GAUCCUUUAGUCCCUCGGAAUUUGAGGCUAGAGGUGCCAGAAAAGUUACCACAGGGAUAA
CUGGCUUGUGGCAGUCAAGCGUUCAUAGCGACAUUGCUUUUUGAUUCUUCGAUGUCGGCU
CUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUUGUUCACCCACUAAUAGGGA
ACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAAUGUUA
CCGCAAUAGUAAUUGAACUUAGUACGAGAGGAACAGUUCAUUCGGAUAAUUGGUUUUUGC
GGCUGUCUGAUCAGGCAUUGCCGCGAAGCUACCAUCCGCUGGAUUAUGGCUGAACGCCUC
UAAGUCAGAAUCCAUGCUAGAACGCGGUGAUUUCUUUGCUCCACACAAUAUAGAUGGAUA
CGAAUAAGGCGUCCUUGUGGCGUCGCUGAACCAUAGCAGGCUAGCAACGGUGCACUUGGC
GGAAAGGCCUUGGGUGCUUGCUGGCGAAUUGCAAUGUCAUUUUGCGUGGGGAUAAAUCAU
UUGUAUACGACUUAGAUGUACAACGGGGUAUUGUAAGCAGUAGAGUAGCCUUGUUGUUAC
GAUCUGCUGAGAUUAAGCCUUUGUUGUCUGAUUUGU
Sequence of entity 3 (2), FASTA
>7UQB_3 5.8S rRNA (chains 2)
AAACUUUCAACAACGGAUCUCUUGGUUCUCGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
ACGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCC
UUGGUAUUCCAGGGGGCAUGCCUGUUUGAGCGUCAUUU
Sequence of entity 4 (3), FASTA
>7UQB_4 5S rRNA (chains 3)
GGUUGCGGCCAUAUCUACCAGAAAGCACCGUUUCCCGUCCGAUCAACUGUAGUUAAGCUG
GUAAGAGCCUGACCGAGUAGUGUAGUGGGUGACCAUACGCGAAACUCAGGUGCUGCAAUC
U
Sequence of entity 5 (5), FASTA
>7UQB_5 rRNA-processing protein (chains 5)
MVNETGESQKAAKGTPVSGKVWKAEKTPLRAKSRVVKNKKLTSWELKKQKRLEDKQFKER
LKALKDEKEEARQAKITMLKERREKKEENERYERLAAKMHAKKVERMRRREKRNKALKER
Sequence of entity 6 (6), FASTA
>7UQB_6 ITS2 rRNA (chains 6)
CCUUCUCAAACAUUCUGUUUGGUAGUGAGUGAUACUCUUUGGAGUUAACUUGAAAUUGCU
GGCCUUAAAGCGAA
Sequence of entity 7 (8), FASTA
>7UQB_7 60S ribosomal protein L12-A (chains 8)
MPPKFDPNEVKYLYLRAVGGEVGASAALAPKIGPLGLSPKKVGEDIAKATKEFKGIKVTV
QLKIQNRQAAASVVPSASSLVITALKEPPRDRKKDKNVKHSGNIQLDEIIEIARQMRDKS
FGRTLASVTKEILGTAQSVGCRVDFKNPHDIIEGINAGEIEIPEN
Sequence of entity 8 (9), FASTA
>7UQB_8 Ribosome biogenesis protein ALB1 (chains 9)
MPSKNSINRPKLTSNLHHKVHSLNKKRAQRERAGLLKPARSSVNSKSGEIKSVALDLYFQ
NKKNESQNSTAVTLQNASSSPASITTRTLSKKRAKKIERNLKYATQRKLLVDASAKLEDE
MDIDLDGGKKVKENEKKSSLTLVKEALWSVIDDTASQGLIIENGQGTTLGGPFFP
Sequence of entity 9 (B), FASTA
>7UQB_9 60S ribosomal protein L3 (chains B)
MSHRKYEAPRHGHLGFLPRKRAASIRARVKAFPKDDRSKPVALTSFLGYKAGMTTIVRDL
DRPGSKFHKREVVEAVTVVDTPPVVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYK
NWYKSKKKAFTKYSAKYAQDGAGIERELARIKKYASVVRVLVHTQIRKTPLAQKKAHLAE
IQLNGGSISEKVDWAREHFEKTVAVDSVFEQNEMIDAIAVTKGHGFEGVTHRWGTKKLPR
KTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHSRTSINHKIYRVGKGDDEANGATSFDR
TKKTITPMGGFVHYGEIKNDFIMVKGCIPGNRKRIVTLRKSLYTNTSRKALEEVSLKWID
TASKFGKGRFQTPAEKHAFMGTLKKDL
Sequence of entity 10 (C), FASTA
>7UQB_10 60S ribosomal protein L4-A (chains C)
MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQT
SAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRY
ATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLK
VLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAP
GAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIR
PAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKPAAVFTETLK
HD
Sequence of entity 11 (D), FASTA
>7UQB_11 60S ribosomal protein L5 (chains D)
MAFQKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTNKDI
ICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGLLIARRTLQKLGLDETYK
GVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRF
PGWDFETEEIDPELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIY
TSAHEAIRADPAFKPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ
Sequence of entity 12 (E), FASTA
>7UQB_12 60S ribosomal protein L6-A (chains E)
MSAQKAPKWYPSEDVAALKKTRKAARPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLED
NTLLISGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYFAKEKLTKKEKKEAN
LFPEQQNKEIKAERVEDQKVVDKALIAEIKKTPLLKQYLSASFSLKNGDKPHMLKF
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| B3P | 2-[3-(2-hydroxy-1,1-dihydroxymethyl-ethylamino)-propylamino]-2-hydroxymethyl-pr… | C11 H26 N2 O6 | 3 |
| MG | Magnesium ion | Mg | 81 |
| ZN | Zinc ion | Zn | 5 |
| GDP | Guanosine-5'-diphosphate | C10 H15 N5 O11 P2 | 2 |
| ALF | Tetrafluoroaluminate ion | Al F4 | 1 |
Water and common crystallization additives (K) are not listed.
Primary citation
rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Sekulski, K., Cruz, V.E., Weirich, C.S. et al. Nat Commun (2023) 14:1207-1207. DOI 10.1038/s41467-023-36867-5 · PubMed
Other PDB entries of the same protein (UniProt P0CX45 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 9PN5 1.75 Å, Composite map of hypomethylated 80S ribosome treated with hygromycin B
- 8CCS 1.97 Å, 80S S. cerevisiae ribosome with ligands in hybrid-1 pre-translocation (PRE-H1) complex
- 8CDR 2.04 Å, Translocation intermediate 2 (TI-2) of 80S S. cerevisiae ribosome with ligands and eEF2…
- 8CEH 2.05 Å, Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2…
- 8P8N 2.15 Å, Mouse RPL39 integrated into the yeast 60S ribosomal subunit
- 8PFR 2.15 Å, Mouse RPL39L integrated into the yeast 60S ribosomal subunit
- 8EVT 2.2 Å, Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome…
- 8T2Y 2.2 Å, Hypomethylated yeast 80S bound with cycloheximide, P-site tRNA, and A-site tRNA,…
- 8P8U 2.23 Å, Yeast 60S ribosomal subunit
- 8CGN 2.28 Å, Non-rotated 80S S. cerevisiae ribosome with ligands
- 8ZHC 2.3 Å, pre-frameshift complex of yeast 80S ribosome with eRF1 and mRNA of WNV
- 7UOO 2.34 Å, Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state
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MolViewer shows 7UQB directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.