NMR strucutre of chimeric protein for model of PHD-Stella complex. Determined by solution NMR. Released 7 Dec 2022.
Explore 7XGA in 3D Show helices and sheets RCSB PDB PDBe
7XGA contains 6 α-helices and 4 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 2-4 | 3 | |
| β-strand | 25 | 1 | 1 |
| β-strand | 37-39 | 3 | 1 |
| β-strand | 46-48 | 3 | 1 |
| α-helix | 68-72 | 5 | |
| β-strand | 89 | 1 | 1 |
| α-helix | 90-93 | 4 | |
| α-helix | 97-101 | 5 | |
| α-helix | 102-106 | 5 | |
| α-helix | 107-114 | 8 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Chimera of E3 ubiquitin-protein ligase UHRF1 and Developmental pluripotency-associated protein 3 | A | protein | 126 | Mus musculus | Q8QZY3 (AlphaFold model), Q8VDF2 (AlphaFold model) |
>7XGA_1 Chimera of E3 ubiquitin-protein ligase UHRF1 and Developmental pluripotency-associated protein 3 (chains A) GPLGSGPSCRFCKDDENKPCRKCACHVCGGREAPEKQLLCDECDMAFHLYCLKPPLTSVP PEPEWYCPSCRTDSRREVQSAFPKRRVRTLLSVLKDPIAKMRRLVRIEQRQKRLEGNEFE RDSEPF
| ID | Name | Formula | Copies |
|---|---|---|---|
| ZN | Zinc ion | Zn | 3 |
Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger. Hata, K., Kobayashi, N., Sugimura, K. et al. Nucleic Acids Res (2022) 50:12527-12542. DOI 10.1093/nar/gkac1082 · PubMed
Other PDB entries of the same protein (UniProt Q8QZY3 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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